Results 21 to 30 of about 30,573 (303)

Evolution of Biochip Technology: A Review from Lab-on-a-Chip to Organ-on-a-Chip

Micromachines, 2020
Following the advancements in microfluidics and lab-on-a-chip (LOC) technologies, a novel biomedical application for microfluidic based devices has emerged in recent years and microengineered cell culture platforms have been created. These micro-devices,
Neda Azizipour, Rahi Avazpour, Derek H. Rosenzweig, M. Sawan, A. Ajji   +4 more
semanticscholar   +1 more source

Molecular fingerprints of nuclear genome and mitochondrial genome for early diagnosis of lung adenocarcinoma

Journal of Translational Medicine, 2023
Background Lung adenocarcinoma (LUAD) is the most prevalent subtype of lung cancer with high morbidity and mortality rates. Due to the heterogeneity of LUAD, its characteristics remain poorly understood.
Yichun Xu, Yong Yang, Yichao Wang, Jun Su, Tianlong Chan, Jiajing Zhou, Yi Gong, Ke Wang, Yifeng Gu, Congmeng Zhang, Guanjin Wu, Ling Bi, Xiong Qin, Junsong Han   +13 more
doaj   +1 more source

Prognostic Pathways Guide Drug Indications in Pan-Cancers

Frontiers in Oncology, 2022
Pathway-level analysis is a powerful approach enabling the interpretation of post-genomic data at a higher level than that of individual molecules. Molecular-targeted therapy focusing on cascade signaling pathways has become a new paradigm in anticancer ...
Fanlin Meng, Fanlin Meng, Kenan Zhang, Changlin Yang, Ke Zhang, Quan Xu, Ruifang Ren, Yiming Zhou, Yimin Sun, Yimin Sun, Yan Peng, Yanze Li, Hongyan Guo, Yonghong Ren, Zheng Zhao   +14 more
doaj   +1 more source

Wenshenyang recipe treats infertility through hormonal regulation and inflammatory responses revealed by transcriptome analysis and network pharmacology

Frontiers in Pharmacology, 2022
The Wenshenyang recipe (WSYR) has the effect of treating infertility, but the mechanisms underlying this activity have not been fully elucidated. In this study, network pharmacology and RNA sequencing were combined, with database-based “dry” experiments ...
Lan Xie, Lan Xie, Shuai Zhao, Xiaoling Zhang, Wenting Huang, Wenting Huang, Liansheng Qiao, Liansheng Qiao, Delin Zhan, Chengmei Ma, Wei Gong, Honglei Dang, Hua Lu   +12 more
doaj   +1 more source

Co-detection: Ultra-reliable Nanoparticle-Based Electrical Detection of Biomolecules in the Presence of Large Background Interference [PDF]

, 2010
Contrary to popular belief, we report that background interference in conductimetric biochips can be exploited using a novel "co-detection" principle to significantly improve the reliability of detecting trace quantities of biomolecules.
Evangelyn Alocilja, Shantanu Chakrabartty, Yang Liu   +2 more
core   +2 more sources

A novel cassette method for probe evaluation in the designed biochips [PDF]

, 2014
A critical step in biochip design is the selection of probes with identical hybridisation characteristics. In this article we describe a novel method for evaluating DNA hybridisation probes, allowing the fine-tuning of biochips, that uses cassettes with ...
Al-humam, Abdulmohsen A., Alkhalil, Samia, Asatiani, Nino, Bogdarina, Irina, Kartvelishvili, Tamar, Mitchell, Julian, Sapojnikova, Nelly, Zinkevich, Vitaly   +7 more
core   +4 more sources

In situ mixing of organic matter decreases hydraulic conductivity of denitrification walls in sand aquifers [PDF]

, 2008
In a previous study, a denitrification wall was constructed in a sand aquifer using sawdust as the carbon substrate. Ground water bypassed around this sawdust wall due to reduced hydraulic conductivity.
Barkle, Gregory F., Burgess, Craig P., Painter, Brett D.M., Schipper, Louis A.   +3 more
core   +2 more sources

Minimization of MEDA Biochip-Size in Droplet Routing

Biosensors, 2022
With the increasing demand for fast, accurate, and reliable biological sensor systems, miniaturized systems have been aimed at droplet-based sensor systems and have been promising.
Chiharu Shiro, Hiroki Nishikawa, Xiangbo Kong, Hiroyuki Tomiyama, Shigeru Yamashita   +4 more
doaj   +1 more source

Editorial Perspective: Advancements in Microfluidics and Biochip Technologies. [PDF]

Micromachines (Basel)
Ryu H, Jeon TJ, Kim SM.
europepmc   +3 more sources

Elevated expression of exosomal microRNA-21 as a potential biomarker for the early diagnosis of pancreatic cancer using a tethered cationic lipoplex nanoparticle biochip

Oncology Letters, 2020
Pancreatic cancer (PC) has a poor prognosis due to the lack of effective molecular biomarkers for early diagnosis. Recent studies have investigated the use of exosomal microRNAs (exmiRs) as diagnostic biomarkers in cancer.
Xiaofan Pu, Guo-ping Ding, Ming-Yao Wu, Senhao Zhou, Shengnan Jia, Liping Cao   +5 more
semanticscholar   +1 more source