Results 91 to 100 of about 9,219 (186)

Surface Plasmon Resonance‐based Biosensing Towards the Detection of Multidrug‐Resistant Tuberculosis

open access: yesAdvanced Photonics Research, Volume 7, Issue 3, March 2026.
This study presents the detection of multidrug‐resistant tuberculosis (MDR‐TB) gene targets (InhA, KatG, and RpoB) and their mutations using a surface plasmon resonance (SPR)‐based biosensing platform to monitor target binding on functionalized sensor chips.
Sipho H. Chauke   +6 more
wiley   +1 more source

Comparative Assessment of Gold Nanoparticle–Antibody Conjugates with Two Differently Shaped Particles for Multimodal Colorimetric Lateral Flow Assay

open access: yesProceedings
Novel detection strategies that exploit the unique properties of gold nanoparticles (AuNPs) hold great potential for the advancement of point-of-care (POC) diagnostics, such as lateral flow and dipstick immunoassay [...]
Vinayak Sharma, Bilal Javed, Furong Tian
doaj   +1 more source

Rational Design of Optical Single‐Walled Carbon Nanotube‐Based Nanosensors with Biological Recognition Elements

open access: yesAdvanced Sensor Research, Volume 5, Issue 3, March 2026.
This Review focuses on assessing and providing perspective on the field of rationally‐designed optical sensors constructed with single‐walled carbon nanotubes. The literature is reviewed and evaluated for SWCNT‐based sensors constructed with biomolecular recognition elements, including proteins, peptides, and oligonucleotides, as well as their methods ...
Amelia K. Ryan   +4 more
wiley   +1 more source

Precision‐Engineered Silver Single‐Atom Carbon Dot Nanozymes for Theranostic Management of Acute Kidney Injury

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
Mitochondria‐targeted silver single‐atom carbon dot (T‐AgSA‐CDs) nanozymes enable dual SOD/GPx‐like ROS scavenging, real‐time imaging, and therapeutic effects for acute kidney injury (AKI). Atomically dispersed Ag sites synergize with carbon dots to restore renal redox hemostasis, protect mitochondrial function, mitigate inflammation, facilitate post ...
Tianle Tang   +10 more
wiley   +1 more source

Click Chemistry and Bioorthogonal Reaction for Aggregation‐Induced Emission Bioconjugates

open access: yesAggregate, Volume 7, Issue 3, March 2026.
This review highlights the construction of AIE active bioconjugates via click chemical or bioorthogonal reactions, and their applications in biosensing, bioimaging, and image‐guided treatment. The challenges and perspectives in the area are also discussed.
Xinzhe Yang   +3 more
wiley   +1 more source

Prolonged Release of IL‐10 From Enzyme‐Mediated Poly‐l‐(Tyrosine‐co‐Phenylalanine) Nanocrystals Enhances Stability and Modulates Inflammatory Responses

open access: yesBiopolymers, Volume 117, Issue 2, March 2026.
Schematic representation of enzyme‐mediated peptide nanocrystal formation and IL‐10 encapsulation, providing stabilized and sustained cytokine delivery that modulates macrophage phenotype and reduces inflammatory responses. ABSTRACT Protease‐catalyzed synthesis of a peptide composed of l‐tyrosine and l‐phenylalanine (2.2:1 M ratio) was achieved in a ...
Fátima Landa‐Tencle   +11 more
wiley   +1 more source

Gold–Thiopurine and Thioguanine Platforms for Chemotherapy and Photodynamic Therapy

open access: yesChemistryEurope, Volume 4, Issue 3, March 2026.
Gold(I)–thiopurine complexes bearing chromophores and phosphine or N‐heterocyclic carbene ligands were developed as multimodal chemo‐photodynamic agents. They show good stability, moderate lipophilicity, and tunable photoresponse. 6‐TG enhances dark cytotoxicity, 6‐MP improves phototoxicity, and PPh3/NBD provide the most efficient photoactivation ...
Laura Agulló   +3 more
wiley   +1 more source

Mausolate Complexes of the Alkaline Earth Metals

open access: yesChemistryEurope, Volume 4, Issue 3, March 2026.
Reliable chelation of Ra2+ for radionuclide therapy has long been a challenge, and the capacious and rigid mausolate ligand may offer a promising approach. We describe herein mausolate complexes with the chemically similar Ba2+, and other group 2 dications, including the introduction of functionalized derivatives. The rapid uptake of alkaline earth (Ae)
Jack F. Smart   +7 more
wiley   +1 more source

Recent Progress on Giant Molecules: Synthesis, Assembly, and Applications

open access: yesChemistry–Methods, Volume 6, Issue 3, March 2026.
Giant molecules are molecules constructed by molecular nanoparticles with precise, rigid structure, have similar structures with small molecules and a large size as macromolecules. In this review, the constituent modules of giant molecules, as well as their synthesis, self‐assembly, applications in various fields and future developing prospect are ...
Haoyu Chen   +7 more
wiley   +1 more source

CRISPR Assays for Protein Detection

open access: yesChemistry–Methods, Volume 6, Issue 3, March 2026.
This review summarizes recent advances in CRISPR–Cas–based strategies for protein detection. Particular focus is placed on recognition element–based approaches, in which antibodies, aptamers, or DNAzymes convert protein binding into CRISPR‐readable nucleic acid signals, and activity‐based strategies that exploit intrinsic protein functions to trigger ...
Luca Capelli   +5 more
wiley   +1 more source

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