Results 11 to 20 of about 9,219 (186)
Development of Bioorthogonal Reactions and Their Applications in Bioconjugation
Molecules, 2015 Biomolecule labeling using chemical probes with specific biological activities has played important roles for the elucidation of complicated biological processes.
Mengmeng Zheng +4 more
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Arylation Chemistry for Bioconjugation [PDF]
Angewandte Chemie International Edition, 2019 AbstractBioconjugation chemistry has been used to prepare modified biomolecules with functions beyond what nature intended. Central to these techniques is the development of highly efficient and selective bioconjugation reactions that operate under mild, biomolecule compatible conditions. Methods that form a nucleophile–sp2 carbon bond show promise for
Chi Zhang +4 more
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Textile Functionalization by Porous Protein Crystal Conjugation and Guest Molecule Loading
Crystals, 2023 Protein crystals are versatile nanostructured materials that can be readily engineered for applications in nanomedicine and nanobiotechnology. Despite their versatility, the small size of typical individual protein crystals (less than one cubic mm ...
Luke F. Hartje +5 more
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Croatica Chemica Acta, 2017 In this review we present our recent contribution to the field of bioorganometallic chemistry of ferrocene. Ferrocene conjugates with biomolecules have been synthesized and characterized using IR and NMR (1H, 13C, COSY, NOESY, HMBC) spectroscopy, ESI-MS and HRMS.
Čakić Semenčić, Mojca +1 more
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Decorating sdAbs with Chelators: Effect of Conjugation on Biodistribution and Functionality
Pharmaceuticals, 2021 Single domain antibodies (sdAbs) have proven to be valuable probes for molecular imaging. In order to produce such probes, one strategy is the functionalization of the reactive amine side chain of lysines with a chelator, resulting in a mixture of ...
Henri Baudhuin +8 more
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Synthesis of Protein-Oligonucleotide Conjugates
Biomolecules, 2022 Nucleic acids and proteins form two of the key classes of functional biomolecules. Through the ability to access specific protein-oligonucleotide conjugates, a broader range of functional molecules becomes accessible which leverages both the ...
Emma E. Watson, Nicolas Winssinger
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Konjugat Poliklonal Antibodi Nanopartikel Emas untuk Deteksi Potato Virus Y
Jurnal Fitopatologi Indonesia, 2020 Polyclonal Antibodi-Gold Nanoparticles for Potato Virus Y Detection Gold nanoparticles are stable colloidal solutions with dimensions of 1-100 nm having surface plasmon resonance with six free electrons.
Ifa Manzila +2 more
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Synthesis, Fluorine-18 Radiolabeling, and In Vivo PET Imaging of a Hydrophilic Fluorosulfotetrazine
Pharmaceuticals, 2023 The development of 18F-fluorotetrazines, suitable for the radiolabeling of biologics such as proteins and antibodies by IEDDA ligation, represents a major challenge, especially for pre-targeting applications.
Jason Beaufrez +3 more
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Carbon Based Nanodots in Early Diagnosis of Cancer
Frontiers in Chemistry, 2021 Detection of cancer at an early stage is one of the principal factors associated with successful treatment outcome. However, current diagnostic methods are not capable of making sensitive and robust cancer diagnosis. Nanotechnology based products exhibit
Gurpal Singh +9 more
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Expanding the chemical diversity of M13 bacteriophage
Frontiers in Microbiology, 2022 Bacteriophage M13 virions are very stable nanoparticles that can be modified by chemical and genetic methods. The capsid proteins can be functionalized in a variety of chemical reactions without loss of particle integrity.
Grace L. Allen +6 more
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