Results 71 to 80 of about 9,219 (186)

Instant Candida albicans Detection Using Ultra-Stable Aptamer Conjugated Gold Nanoparticles

Micromachines
Fungal pathogens such as Candida albicans have significant impacts on women’s health and the economy worldwide. Current detection methods often require access to laboratory facilities that are costly, inconvenient, and slow to access. This often leads to
Kimberley Clack, Mohamed Sallam, Serge Muyldermans, Prabhakaran Sambasivam, Cong Minh Nguyen, Nam-Trung Nguyen   +5 more
doaj   +1 more source

Glucosylation and Glutathione Conjugation of Chlorpyrifos and Fluopyram Metabolites Using Electrochemistry/Mass Spectrometry

Molecules, 2019
Xenobiotics and their reactive metabolites are conjugated with native biomolecules such as glutathione and glucoside during phase II metabolism. Toxic metabolites are usually detoxified during this step.
Tessema Fenta Mekonnen, Ulrich Panne, Matthias Koch   +2 more
doaj   +1 more source

Extracellular and Membrane Protein: Structure, Biological Functions, Diseases, and an Emerging Modality for Drug Discovery

MedComm, Volume 7, Issue 4, April 2026.
Targeted protein degradation represents a paradigm shift from traditional protein inhibition to complete protein elimination. This is achieved through three main strategies for degrading extracellular and membrane proteins: recruitment of cell‐surface LTRs, engagement of intracellular proteins, and receptor‐independent mechanisms.
Mengqing Zhao, Wenhao Yin, Jianjian Han, Huimin Wang, Zheng Liu, Lilong Liu, Wuxiang Mao   +6 more
wiley   +1 more source

Antimicrobial Peptides: Diversity, Mechanism of Action and Strategies to Improve the Activity and Biocompatibility In Vivo

Biomolecules, 2018
Antibiotic resistance is projected as one of the greatest threats to human health in the future and hence alternatives are being explored to combat resistance.
Prashant Kumar, Jayachandran N. Kizhakkedathu, Suzana K. Straus   +2 more
doaj   +1 more source

Generating Ultra‐Fast Protein trans‐Splicing of a Cysteine‐Less and Semisynthetic Split Intein for Chemical Protein Labeling

ChemBioChem, Volume 27, Issue 6, 27 March 2026.
Protein trans‐splicing (PTS) by split inteins is a powerful approach for protein semisynthesis to generate proteins with site‐specific modifications that are difficult or impossible to introduce biosynthetically. Here, the authors report the first ultra‐fast and cysteine‐less split intein with a sufficiently short N‐terminal fragment amenable to ...
Christoph Humberg, Tobias M. E. Terhorst, Tim Pasch, Henning D. Mootz   +3 more
wiley   +1 more source

Conjugation of Polymer-Coated Gold Nanoparticles with Antibodies—Synthesis and Characterization

Nanomaterials, 2015
The synthesis of polymer-coated gold nanoparticles with high colloidal stability is described, together with appropriate characterization techniques concerning the colloidal properties of the nanoparticles.
Gamze Tan, Karsten Kantner, Qian Zhang, Mahmoud G. Soliman, Pablo del Pino, Wolfgang J. Parak, Mehmet A. Onur, Daniel Valdeperez, Joanna Rejman, Beatriz Pelaz   +9 more
doaj   +1 more source

Synthesis of Peptide Bioconjugates [PDF]

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
openaire   +2 more sources

Biomimetic Construction of Abiotic Membranes Through Acylation of Cationic Diamino Acids

ChemBioChem, Volume 27, Issue 6, 27 March 2026.
Cells produce membrane‐forming phospholipids through complex enzymatic pathways. Here, we present the in situ synthesis of a novel class of abiotic phospholipid analogs (APAs) featuring a permanent choline‐mimetic cation on diamino acid backbones.
Federica A. Souto‐Trinei, Bruno Delgado Gonzalez, Roberto J. Brea   +2 more
wiley   +1 more source

From Conjugation to Detection: Development of Lateral Flow Assay for Zearalenone

ChemEngineering
The development of rapid, sensitive and cost-effective lateral flow assays is crucial for the detection of mycotoxins, ideally at the point-of-care level.
Vinayak Sharma, Bilal Javed, Hugh J. Byrne, Furong Tian   +3 more
doaj   +1 more source

More Than a Buffer in Biochemistry: Tris as an Architect and Gatekeeper of Metal–Oxo Assembly

Angewandte Chemie International Edition, Volume 65, Issue 13, 23 March 2026.
Tris(hydroxymethyl)aminomethane, depicted as an octopus, acts as an alkoxy ligand, chelator, and structure‐directing buffer that programs polyoxometalate's speciation, nucleation, and heterometal insertion in aqueous solution. ABSTRACT Polyoxometalates (POMs, molecular metal–oxo clusters) are typically studied and applied in aqueous media, where ...
Nadiia I. Gumerova, Annette Rompel
wiley   +1 more source