Results 101 to 110 of about 2,351 (208)

The art of curation at a biological database: Principles and application

open access: yesCurrent Plant Biology, 2017
The variety and quantity of data being produced by biological research has grown dramatically in recent years, resulting in an expansion of our understanding of biological systems. However, this abundance of data has brought new challenges, especially in
Sarah G. Odell   +4 more
doaj   +1 more source

A quick guide for student-driven community genome annotation

open access: yes, 2018
High quality gene models are necessary to expand the molecular and genetic tools available for a target organism, but these are available for only a handful of model organisms that have undergone extensive curation and experimental validation over the ...
Benoit, Joshua B.   +10 more
core   +2 more sources

Jointly creating digital abstracts: dealing with synonymy and polysemy

open access: yesBMC Research Notes, 2012
Background Ideally each Life Science article should get a ‘structured digital abstract’. This is a structured summary of the paper’s findings that is both human-verified and machine-readable.
Vercruysse Steven, Kuiper Martin
doaj   +1 more source

COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms

open access: yesMolecular Systems Biology, 2021
We need to effectively combine the knowledge from surging literature with complex datasets to propose mechanistic models of SARS‐CoV‐2 infection, improving data interpretation and predicting key targets of intervention.
Marek Ostaszewski   +139 more
doaj   +1 more source

Biocuration with insufficient resources and fixed timelines [PDF]

open access: yesDatabase, 2015
Biological curation, or biocuration, is often studied from the perspective of creating and maintaining databases that have the goal of mapping and tracking certain areas of biology. However, much biocuration is, in fact, dedicated to finite and time-limited projects in which insufficient resources demand trade-offs.
openaire   +3 more sources

IMGT® Biocuration and Comparative Study of the T Cell Receptor Beta Locus of Veterinary Species Based on Homo sapiens TRB

open access: yesFrontiers in Immunology, 2020
IMGT®, the international ImMunoGeneTics information system® is the global reference in immunogenetics and immunoinformatics. By its creation in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS), IMGT® marked the advent of immunoinformatics,
Perrine Pégorier   +10 more
doaj   +1 more source

Overview of the interactive task in BioCreative V [PDF]

open access: yes, 2016
Fully automated text mining (TM) systems promote efficient literature searching, retrieval, and review but are not sufficient to produce ready-to-consume curated documents. These systems are not meant to replace biocurators, but instead to assist them in
Van Auken, Kimberly   +2 more
core  

Integrated Analysis of microRNA Targets Reveals New Insights into Transcriptional–Post-Transcriptional Regulatory Cross-Talk

open access: yesBiology
It is becoming increasingly clear that microRNAs are key players in gene regulatory networks, modulating gene expression at post-transcriptional level.
Simona Panni, Roberto Pizzolotto
doaj   +1 more source

Manually Curated Database of Rice Proteins (MCDRP), a database of digitized experimental data on rice

open access: yesCurrent Plant Biology, 2016
MCDRP or ‘Manually Curated Database of Rice Proteins’ is a database of digitized experimental datasets on rice proteins. Every aspect of the experimental data published in peer-reviewed research articles on rice biology has been digitized with the help ...
Saurabh Raghuvanshi   +2 more
doaj   +1 more source

Automation of gene function prediction through modeling human curators' decisions in GO phylogenetic annotation project [PDF]

open access: yesarXiv, 2018
The Gene Ontology Consortium launched the GO-PAINT project (Phylogenetic Annotation and INference Tool) 9 years ago and is currently being used in the GO Reference Genome Annotation Project to support inference of GO function terms (molecular function, cellular component and biological process) by homology. PAINT uses a phylogenetic model to infer gene
arxiv  

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