Results 81 to 90 of about 1,399 (186)

CardioTF, a database of deconstructing transcriptional circuits in the heart system [PDF]

open access: yesPeerJ, 2016
Background: Information on cardiovascular gene transcription is fragmented and far behind the present requirements of the systems biology field. To create a comprehensive source of data for cardiovascular gene regulation and to facilitate a deeper ...
Yisong Zhen
doaj   +2 more sources

Mechanisms of action of monoclonal antibodies in oncology integrated in IMGT/mAb-DB

open access: yesFrontiers in Immunology, 2023
BackgroundCancer cells activate different immune checkpoint (IC) pathways in order to evade immunosurveillance. Immunotherapies involving ICs either block or stimulate these pathways and enhance the efficiency of the immune system to recognize and attack
Taciana Manso   +5 more
doaj   +1 more source

Databases and bioinformatics tools for rice research

open access: yesCurrent Plant Biology, 2016
Rice is one of the most important agricultural crop in the world and widely studied model plant. The completion of whole genome sequence of rice (Oryza sativa) and high-throughput experimental platforms have led to the generation of the tremendous amount
Priyanka Garg, Pankaj Jaiswal
doaj   +1 more source

Text-mining-assisted biocuration workflows in Argo [PDF]

open access: yesDatabase, 2014
Les activités de biocuration ont été largement classées dans la sélection des documents pertinents, l'annotation des concepts biologiques d'intérêt et l'identification des interactions entre les concepts. Il a été démontré que l'exploration de texte avait le potentiel de réduire considérablement l'effort des biocurateurs dans les trois activités, et ...
Rafał Rak   +4 more
openaire   +3 more sources

Jointly creating digital abstracts: dealing with synonymy and polysemy

open access: yesBMC Research Notes, 2012
Background Ideally each Life Science article should get a ‘structured digital abstract’. This is a structured summary of the paper’s findings that is both human-verified and machine-readable.
Vercruysse Steven, Kuiper Martin
doaj   +1 more source

C/VDdb: A multi-omics expression profiling database for a knowledge-driven approach in cardiovascular disease (CVD). [PDF]

open access: yesPLoS ONE, 2018
The cardiovascular disease (C/VD) database is an integrated and clustered information resource that covers multi-omic studies (microRNA, genomics, proteomics and metabolomics) of cardiovascular-related traits with special emphasis on coronary artery ...
Marco Fernandes   +2 more
doaj   +1 more source

Integrating text mining into the MGI biocuration workflow [PDF]

open access: yesDatabase, 2009
AbstractA major challenge for the development of resources for functional and comparative genomics is the extraction of data from the biomedical literature. Although text retrieval and extraction for biological data is an active research field, few applications have been integrated into production literature curation systems such as those of the model ...
Karen G. Dowell   +4 more
openaire   +3 more sources

Mapping the landscape of biocuration – where are the biocurators and what do they need?

open access: yes, 2019
These slides were presented as part of a workshop on ‘Mapping the landscape of biocuration’ at the Biocuration 2019 conference. This work forms part of an ELIXIR Implementation Study. The slides are a summary of the preliminary analysis of a survey conducted by ELIXIR and the International Society of Biocuration which was designed to map the landscape ...
Holinski, Alexandra   +4 more
openaire   +1 more source

Integrated Analysis of microRNA Targets Reveals New Insights into Transcriptional–Post-Transcriptional Regulatory Cross-Talk

open access: yesBiology
It is becoming increasingly clear that microRNAs are key players in gene regulatory networks, modulating gene expression at post-transcriptional level.
Simona Panni, Roberto Pizzolotto
doaj   +1 more source

The art of curation at a biological database: Principles and application

open access: yesCurrent Plant Biology, 2017
The variety and quantity of data being produced by biological research has grown dramatically in recent years, resulting in an expansion of our understanding of biological systems. However, this abundance of data has brought new challenges, especially in
Sarah G. Odell   +4 more
doaj   +1 more source

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