Results 1 to 10 of about 463,290 (301)

Logical Gene Ontology Annotations (GOAL): exploring gene ontology annotations with OWL [PDF]

Journal of Biomedical Semantics, 2012
Motivation Ontologies such as the Gene Ontology (GO) and their use in annotations make cross species comparisons of genes possible, along with a wide range of other analytical activities.
Jupp Simon, Stevens Robert, Hoehndorf Robert   +2 more
doaj   +4 more sources

How the gene ontology evolves [PDF]

BMC Bioinformatics, 2011
Background Maintaining a bio-ontology in the long term requires improving and updating its contents so that it adequately captures what is known about biological phenomena.
Leonelli Sabina, Diehl Alexander D, Christie Karen R, Harris Midori A, Lomax Jane   +4 more
doaj   +4 more sources

The Gene Ontology knowledgebase in 2023. [PDF]

Genetics, 2023
Abstract The Gene Ontology (GO) knowledgebase (http://geneontology.org) is a comprehensive resource concerning the functions of genes and gene products (proteins and noncoding RNAs). GO annotations cover genes from organisms across the tree of life as well as viruses, though most gene function knowledge currently derives from experiments
Gene Ontology Consortium, Aleksander SA, Balhoff J, Carbon S, Cherry JM, Drabkin HJ, Ebert D, Feuermann M, Gaudet P, Harris NL, Hill DP, Lee R, Mi H, Moxon S, Mungall CJ, Muruganugan A, Mushayahama T, Sternberg PW, Thomas PD, Van Auken K, Ramsey J, Siegele DA, Chisholm RL, Fey P, Aspromonte MC, Nugnes MV, Quaglia F, Tosatto S, Giglio M, Nadendla S, Antonazzo G, Attrill H, Dos Santos G, Marygold S, Strelets V, Tabone CJ, Thurmond J, Zhou P, Ahmed SH, Asanitthong P, Luna Buitrago D, Erdol MN, Gage MC, Ali Kadhum M, Li KYC, Long M, Michalak A, Pesala A, Pritazahra A, Saverimuttu SCC, Su R, Thurlow KE, Lovering RC, Logie C, Oliferenko S, Blake J, Christie K, Corbani L, Dolan ME, Drabkin HJ, Hill DP, Ni L, Sitnikov D, Smith C, Cuzick A, Seager J, Cooper L, Elser J, Jaiswal P, Gupta P, Jaiswal P, Naithani S, Lera-Ramirez M, Rutherford K, Wood V, De Pons JL, Dwinell MR, Hayman GT, Kaldunski ML, Kwitek AE, Laulederkind SJF, Tutaj MA, Vedi M, Wang SJ, D'Eustachio P, Aimo L, Axelsen K, Bridge A, Hyka-Nouspikel N, Morgat A, Aleksander SA, Cherry JM, Engel SR, Karra K, Miyasato SR, Nash RS, Skrzypek MS, Weng S, Wong ED, Bakker E, Berardini TZ, Reiser L, Auchincloss A, Axelsen K, Argoud-Puy G, Blatter MC, Boutet E, Breuza L, Bridge A, Casals-Casas C, Coudert E, Estreicher A, Livia Famiglietti M, Feuermann M, Gos A, Gruaz-Gumowski N, Hulo C, Hyka-Nouspikel N, Jungo F, Le Mercier P, Lieberherr D, Masson P, Morgat A, Pedruzzi I, Pourcel L, Poux S, Rivoire C, Sundaram S, Bateman A, Bowler-Barnett E, Bye-A-Jee H, Denny P, Ignatchenko A, Ishtiaq R, Lock A, Lussi Y, Magrane M, Martin MJ, Orchard S, Raposo P, Speretta E, Tyagi N, Warner K, Zaru R, Diehl AD, Lee R, Chan J, Diamantakis S, Raciti D, Zarowiecki M, Fisher M, James-Zorn C, Ponferrada V, Zorn A, Ramachandran S, Ruzicka L, Westerfield M.   +156 more
europepmc   +9 more sources

Capturing heart valve development with Gene Ontology [PDF]

Frontiers in Genetics, 2023
Introduction: The normal development of all heart valves requires highly coordinated signaling pathways and downstream mediators. While genomic variants can be responsible for congenital valve disease, environmental factors can also play a role. Later in
Saadullah H. Ahmed, Alexander T. Deng, Rachael P. Huntley, Nancy H. Campbell, Ruth C. Lovering   +4 more
doaj   +2 more sources

From Plant Ontology to Gene Ontology and back

Current Plant Biology, 2018
Our recent goal for the Plant Ontology (PO) is to have it integrated with the Gene Ontology (GO). The simplest aspect of this is to link morphological and anatomical images of structures for PO terms with genes involved in the development of those ...
Dennis Stevenson, Cecilia Zumajo-Cardona
doaj   +3 more sources

Comparative GO: a web application for comparative gene ontology and gene ontology-based gene selection in bacteria.

PLoS ONE, 2013
UnlabelledThe primary means of classifying new functions for genes and proteins relies on Gene Ontology (GO), which defines genes/proteins using a controlled vocabulary in terms of their Molecular Function, Biological Process and Cellular Component.
Mario Fruzangohar, Esmaeil Ebrahimie, Abiodun D Ogunniyi, Layla K Mahdi, James C Paton, David L Adelson   +5 more
doaj   +6 more sources

The Gene Ontology's Reference Genome Project: a unified framework for functional annotation across species. [PDF]

PLoS Computational Biology, 2009
The Gene Ontology (GO) is a collaborative effort that provides structured vocabularies for annotating the molecular function, biological role, and cellular location of gene products in a highly systematic way and in a species-neutral manner with the aim ...
Reference Genome Group of the Gene Ontology Consortium
doaj   +1 more source

Bringing ontology to the Gene Ontology [PDF]

Comparative and Functional Genomics, 2003
AbstractWe present an analysis of some considerations involved in expressing the Gene Ontology (GO) as a machine‐processible ontology, reflecting principles of formal ontology. GO is a controlled vocabulary that is intended to facilitate communication between biologists by standardizing usage of terms in database annotations.
Williams, Jennifer, Andersen, William
openaire   +2 more sources

The Gene Ontology Categorizer [PDF]

Bioinformatics, 2004
Abstract Summary: The Gene Ontology Categorizer, developed jointly by the Los Alamos National Laboratory and Procter & Gamble Corp., provides a capability for the categorization task in the Gene Ontology (GO): given a list of genes of interest, what are the best nodes of the GO to summarize or categorize that list?
Cliff A, Joslyn, Susan M, Mniszewski, Andy, Fulmer, Gary, Heaton   +3 more
openaire   +2 more sources

Ontologizing gene-expression microarray data: characterizing clusters with Gene Ontology [PDF]

Bioinformatics, 2004
Abstract Summary: An XML-based Java application is described that provides a function-oriented overview of the results of cluster analysis of gene-expression microarray data based on Gene Ontology terms and associations. The application generates one HTML page with listings of the frequencies of explicit and implicit Gene Ontology ...
Peter N, Robinson, Andreas, Wollstein, Ulrike, Böhme, Brad, Beattie   +3 more
openaire   +2 more sources