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The Neural/Immune Gene Ontology: clipping the Gene Ontology for neurological and immunological systems [PDF]

open access: yesBMC Bioinformatics, 2010
Background The Gene Ontology (GO) is used to describe genes and gene products from many organisms. When used for functional annotation of microarray data, GO is often slimmed by editing so that only higher level terms remain. This practice is designed to
Rubin Eitan   +2 more
doaj   +4 more sources

Measuring the evolution of ontology complexity: the gene ontology case study. [PDF]

open access: yesPLoS ONE, 2013
Ontologies support automatic sharing, combination and analysis of life sciences data. They undergo regular curation and enrichment. We studied the impact of an ontology evolution on its structural complexity.
Olivier Dameron   +2 more
doaj   +7 more sources

Capturing heart valve development with Gene Ontology [PDF]

open access: yesFrontiers in Genetics, 2023
Introduction: The normal development of all heart valves requires highly coordinated signaling pathways and downstream mediators. While genomic variants can be responsible for congenital valve disease, environmental factors can also play a role. Later in
Saadullah H. Ahmed   +4 more
doaj   +2 more sources

The Gene Ontology's Reference Genome Project: a unified framework for functional annotation across species. [PDF]

open access: yesPLoS Computational Biology, 2009
The Gene Ontology (GO) is a collaborative effort that provides structured vocabularies for annotating the molecular function, biological role, and cellular location of gene products in a highly systematic way and in a species-neutral manner with the aim ...
Reference Genome Group of the Gene Ontology Consortium
doaj   +1 more source

Gene Expression Analysis to Mine Highly Relevant Gene Data in Chronic Diseases and Annotating its GO Terms [PDF]

open access: yesEAI Endorsed Transactions on Energy Web, 2020
Gene Expression Analysis seeks to find the highly expressive genes from a highly dimensional Microarray disease gene Database by using some statistical gene selection approaches based on supervised or unsupervised learning.
J. Bell, S. Vigila
doaj   +1 more source

Mining Gene Ontology Data with AGENDA

open access: yesBioinformatics and Biology Insights, 2012
The Gene Ontology (GO) initiative is a collaborative effort that uses controlled vocabularies for annotating genetic information. We here present AGENDA ( A pplication for mining Gen e Ontology Da ta), a novel web-based tool for accessing the GO database.
Martin C. Göpfert   +2 more
doaj   +2 more sources

From Plant Ontology to Gene Ontology and back

open access: yesCurrent Plant Biology, 2018
Our recent goal for the Plant Ontology (PO) is to have it integrated with the Gene Ontology (GO). The simplest aspect of this is to link morphological and anatomical images of structures for PO terms with genes involved in the development of those ...
Dennis Stevenson, Cecilia Zumajo-Cardona
doaj   +1 more source

Cross-Ontology multi-level association rule mining in the Gene Ontology. [PDF]

open access: yesPLoS ONE, 2012
The Gene Ontology (GO) has become the internationally accepted standard for representing function, process, and location aspects of gene products. The wealth of GO annotation data provides a valuable source of implicit knowledge of relationships among ...
Prashanti Manda   +4 more
doaj   +1 more source

GOLEM: an interactive graph-based gene-ontology navigation and analysis tool

open access: yesBMC Bioinformatics, 2006
Background The Gene Ontology has become an extremely useful tool for the analysis of genomic data and structuring of biological knowledge. Several excellent software tools for navigating the gene ontology have been developed.
Huttenhower Curtis   +4 more
doaj   +1 more source

Mining the Gene Wiki for functional genomic knowledge

open access: yesBMC Genomics, 2011
Background Ontology-based gene annotations are important tools for organizing and analyzing genome-scale biological data. Collecting these annotations is a valuable but costly endeavor.
Good Benjamin M   +4 more
doaj   +1 more source

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