Results 31 to 40 of about 463,290 (301)
Gene function prediction based on the Gene Ontology hierarchical structure. [PDF]
PLoS ONE, 2014 The information of the Gene Ontology annotation is helpful in the explanation of life science phenomena, and can provide great support for the research of the biomedical field.
Liangxi Cheng +4 more
doaj +1 more source
Onion Extract on Cell Gene Expression Profile: a System Biology Approach [PDF]
Research Journal of Pharmacognosy, 2023 Background and objectives: Widespread consuming of onion as a nutrient in the world implies more investigations about useful and harmful aspects of this common supplementary food.
Babak Arjmand +5 more
doaj +1 more source
GO faster ChEBI with Reasonable Biochemistry [PDF]
, 2008 Chemical Entities of Biological Interest (ChEBI) is a database and ontology that represents biochemical knowledge about small molecules. Recent changes to the ontology have created new opportunities for automated reasoning with description logic, that ...
Duncan Hull
core +2 more sources
Length bias correction in gene ontology enrichment analysis using logistic regression. [PDF]
PLoS ONE, 2012 When assessing differential gene expression from RNA sequencing data, commonly used statistical tests tend to have greater power to detect differential expression of genes encoding longer transcripts. This phenomenon, called "length bias", will influence
Gu Mi +4 more
doaj +1 more source
GOexpress: an R/Bioconductor package for the identification and visualisation of robust gene ontology signatures through supervised learning of gene expression data [PDF]
, 2016 Background: Identification of gene expression profiles that differentiate experimental groups is critical for discovery and analysis of key molecular pathways and also for selection of robust diagnostic or prognostic biomarkers.
Gordon, SV +7 more
core +4 more sources
Gene Ontology Consortium: going forward [PDF]
Nucleic Acids Research, 2014 The Gene Ontology (GO; http://www.geneontology.org) is a community-based bioinformatics resource that supplies information about gene product function using ontologies to represent biological knowledge. Here we describe improvements and expansions to several branches of the ontology, as well as updates that have allowed us to more efficiently ...
Consortium, Gene Ontology +7 more
openaire +4 more sources
, 2009 Vaccine research, as well as the development, testing, clinical trials, and commercial uses of vaccines involve complex processes with various biological data that include gene and protein expression, analysis of molecular and cellular interactions ...
Alan Ruttenberg +20 more
core +3 more sources
Extending gene ontology with gene association networks [PDF]
Bioinformatics, 2015 Abstract Motivation: Gene ontology (GO) is a widely used resource to describe the attributes for gene products. However, automatic GO maintenance remains to be difficult because of the complex logical reasoning and the need of biological knowledge that are not explicitly represented in the GO.
Jiajie, Peng +4 more
openaire +2 more sources
Formalization of gene regulation knowledge using ontologies and gene ontology causal activity models
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2021 Gene regulation computational research requires handling and integrating large amounts of heterogeneous data. The Gene Ontology has demonstrated that ontologies play a fundamental role in biological data interoperability and integration. Ontologies help to express data and knowledge in a machine processable way, which enables complex querying and ...
Cortés, BJ +9 more
openaire +7 more sources
CirGO: an alternative circular way of visualising gene ontology terms
BMC Bioinformatics, 2019 Background Prioritisation of gene ontology terms from differential gene expression analyses in a two-dimensional format remains a challenge with exponentially growing data volumes.
Irina Kuznetsova +4 more
doaj +1 more source