Results 41 to 50 of about 347,215 (296)
The Gene Ontology Annotation (GOA) Database: sharing knowledge in Uniprot with Gene Ontology [PDF]
Nucleic Acids Research, 2004 The Gene Ontology Annotation (GOA) database (http://www.ebi.ac.uk/GOA) aims to provide high-quality electronic and manual annotations to the UniProt Knowledgebase (Swiss-Prot, TrEMBL and PIR-PSD) using the standardized vocabulary of the Gene Ontology (GO).
Evelyn Camon +9 more
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Multi-label literature classification based on the Gene Ontology graph
BMC Bioinformatics, 2008 Background The Gene Ontology is a controlled vocabulary for representing knowledge related to genes and proteins in a computable form. The current effort of manually annotating proteins with the Gene Ontology is outpaced by the rate of accumulation of ...
Lu Xinghua +3 more
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The Gene Ontology in 2010: extensions and refinements.
, 2010 The Gene Ontology (GO) Consortium (http://www.geneontology.org) (GOC) continues to develop, maintain and use a set of structured, controlled vocabularies for the annotation of genes, gene products and sequences. The GO ontologies are expanding both in
Gene, Ontology Consortium
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
A Gene Ontology Tutorial in Python [PDF]
, 2016 This chapter is a tutorial on using Gene Ontology resources in the Python programming language. This entails querying the Gene Ontology graph, retrieving Gene Ontology annotations, performing gene enrichment analyses, and computing basic semantic similarity between GO terms.
Vesztrocy, AW, Dessimoz, C
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Defining functional distances over Gene Ontology
BMC Bioinformatics, 2008 Background A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-structured ontologies exist regarding the activity of proteins (i.e.
del Pozo Angela +2 more
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
On gene ontology and function annotation [PDF]
Bioinformation, 2006 The effort of function annotation does not merely involve associating a gene with some structured vocabulary that describes action. Rather the details of the actions, the components of the actions, the larger context of the actions are important issues that are of direct relevance, because they help understand the biological system to which the gene ...
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Extending gene ontology with gene association networks [PDF]
Bioinformatics, 2015 Abstract Motivation: Gene ontology (GO) is a widely used resource to describe the attributes for gene products. However, automatic GO maintenance remains to be difficult because of the complex logical reasoning and the need of biological knowledge that are not explicitly represented in the GO.
Jiajie Peng +4 more
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MEGO: gene functional module expression based on gene ontology
BioTechniques, 2005 Existing analysis tools to study the collective properties of gene functional modules cannot return highly homogeneous modules and do not provide quantitative measures of module activity level.
Kang Tu, Hui Yu, Mingzhu Zhu
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