Results 11 to 20 of about 307,734 (118)
PLoS Computational Biology, 2012 A recent paper (Nehrt et al., PLoS Comput. Biol. 7:e1002073, 2011) has proposed a metric for the "functional similarity" between two genes that uses only the Gene Ontology (GO) annotations directly derived from published experimental results.
Paul D Thomas +5 more
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Functional-network-based gene set analysis using gene-ontology. [PDF]
PLoS ONE, 2013 To account for the functional non-equivalence among a set of genes within a biological pathway when performing gene set analysis, we introduce GOGANPA, a network-based gene set analysis method, which up-weights genes with functions relevant to the gene ...
Billy Chang, Rafal Kustra, Weidong Tian
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Construction of ontology augmented networks for protein complex prediction.
PLoS ONE, 2013 Protein complexes are of great importance in understanding the principles of cellular organization and function. The increase in available protein-protein interaction data, gene ontology and other resources make it possible to develop computational ...
Yijia Zhang +3 more
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Disjunctive shared information between ontology concepts: application to Gene Ontology
Journal of Biomedical Semantics, 2011 Background The large-scale effort in developing, maintaining and making biomedical ontologies available motivates the application of similarity measures to compare ontology concepts or, by extension, the entities described therein.
Couto Francisco M, Silva Mário J
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Gene function prediction based on the Gene Ontology hierarchical structure. [PDF]
PLoS ONE, 2014 The information of the Gene Ontology annotation is helpful in the explanation of life science phenomena, and can provide great support for the research of the biomedical field.
Liangxi Cheng +4 more
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Onion Extract on Cell Gene Expression Profile: a System Biology Approach [PDF]
Research Journal of Pharmacognosy, 2023 Background and objectives: Widespread consuming of onion as a nutrient in the world implies more investigations about useful and harmful aspects of this common supplementary food.
Babak Arjmand +5 more
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BMC Bioinformatics, 2011 Background Maintaining a bio-ontology in the long term requires improving and updating its contents so that it adequately captures what is known about biological phenomena.
Leonelli Sabina +4 more
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Length bias correction in gene ontology enrichment analysis using logistic regression. [PDF]
PLoS ONE, 2012 When assessing differential gene expression from RNA sequencing data, commonly used statistical tests tend to have greater power to detect differential expression of genes encoding longer transcripts. This phenomenon, called "length bias", will influence
Gu Mi +4 more
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PLoS ONE, 2013 UnlabelledThe primary means of classifying new functions for genes and proteins relies on Gene Ontology (GO), which defines genes/proteins using a controlled vocabulary in terms of their Molecular Function, Biological Process and Cellular Component.
Mario Fruzangohar +5 more
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CirGO: an alternative circular way of visualising gene ontology terms
BMC Bioinformatics, 2019 Background Prioritisation of gene ontology terms from differential gene expression analyses in a two-dimensional format remains a challenge with exponentially growing data volumes.
Irina Kuznetsova +4 more
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