Results 11 to 20 of about 308,702 (255)

Measuring the evolution of ontology complexity: the gene ontology case study. [PDF]

PLoS ONE, 2013
Ontologies support automatic sharing, combination and analysis of life sciences data. They undergo regular curation and enrichment. We studied the impact of an ontology evolution on its structural complexity.
Olivier Dameron, Charles Bettembourg, Nolwenn Le Meur   +2 more
doaj   +9 more sources

How the gene ontology evolves [PDF]

BMC Bioinformatics, 2011
Background Maintaining a bio-ontology in the long term requires improving and updating its contents so that it adequately captures what is known about biological phenomena.
Leonelli Sabina, Diehl Alexander D, Christie Karen R, Harris Midori A, Lomax Jane   +4 more
doaj   +4 more sources

The Gene Ontology knowledgebase in 2023. [PDF]

Genetics, 2023
Abstract The Gene Ontology (GO) knowledgebase (http://geneontology.org) is a comprehensive resource concerning the functions of genes and gene products (proteins and noncoding RNAs). GO annotations cover genes from organisms across the tree of life as well as viruses, though most gene function knowledge currently derives from experiments
Gene Ontology Consortium, Aleksander SA, Balhoff J, Carbon S, Cherry JM, Drabkin HJ, Ebert D, Feuermann M, Gaudet P, Harris NL, Hill DP, Lee R, Mi H, Moxon S, Mungall CJ, Muruganugan A, Mushayahama T, Sternberg PW, Thomas PD, Van Auken K, Ramsey J, Siegele DA, Chisholm RL, Fey P, Aspromonte MC, Nugnes MV, Quaglia F, Tosatto S, Giglio M, Nadendla S, Antonazzo G, Attrill H, Dos Santos G, Marygold S, Strelets V, Tabone CJ, Thurmond J, Zhou P, Ahmed SH, Asanitthong P, Luna Buitrago D, Erdol MN, Gage MC, Ali Kadhum M, Li KYC, Long M, Michalak A, Pesala A, Pritazahra A, Saverimuttu SCC, Su R, Thurlow KE, Lovering RC, Logie C, Oliferenko S, Blake J, Christie K, Corbani L, Dolan ME, Drabkin HJ, Hill DP, Ni L, Sitnikov D, Smith C, Cuzick A, Seager J, Cooper L, Elser J, Jaiswal P, Gupta P, Jaiswal P, Naithani S, Lera-Ramirez M, Rutherford K, Wood V, De Pons JL, Dwinell MR, Hayman GT, Kaldunski ML, Kwitek AE, Laulederkind SJF, Tutaj MA, Vedi M, Wang SJ, D'Eustachio P, Aimo L, Axelsen K, Bridge A, Hyka-Nouspikel N, Morgat A, Aleksander SA, Cherry JM, Engel SR, Karra K, Miyasato SR, Nash RS, Skrzypek MS, Weng S, Wong ED, Bakker E, Berardini TZ, Reiser L, Auchincloss A, Axelsen K, Argoud-Puy G, Blatter MC, Boutet E, Breuza L, Bridge A, Casals-Casas C, Coudert E, Estreicher A, Livia Famiglietti M, Feuermann M, Gos A, Gruaz-Gumowski N, Hulo C, Hyka-Nouspikel N, Jungo F, Le Mercier P, Lieberherr D, Masson P, Morgat A, Pedruzzi I, Pourcel L, Poux S, Rivoire C, Sundaram S, Bateman A, Bowler-Barnett E, Bye-A-Jee H, Denny P, Ignatchenko A, Ishtiaq R, Lock A, Lussi Y, Magrane M, Martin MJ, Orchard S, Raposo P, Speretta E, Tyagi N, Warner K, Zaru R, Diehl AD, Lee R, Chan J, Diamantakis S, Raciti D, Zarowiecki M, Fisher M, James-Zorn C, Ponferrada V, Zorn A, Ramachandran S, Ruzicka L, Westerfield M.   +156 more
europepmc   +9 more sources

Logical Gene Ontology Annotations (GOAL): exploring gene ontology annotations with OWL [PDF]

Journal of Biomedical Semantics, 2012
Motivation Ontologies such as the Gene Ontology (GO) and their use in annotations make cross species comparisons of genes possible, along with a wide range of other analytical activities.
Jupp Simon, Stevens Robert, Hoehndorf Robert   +2 more
doaj   +5 more sources

The Neural/Immune Gene Ontology: clipping the Gene Ontology for neurological and immunological systems [PDF]

BMC Bioinformatics, 2010
Background The Gene Ontology (GO) is used to describe genes and gene products from many organisms. When used for functional annotation of microarray data, GO is often slimmed by editing so that only higher level terms remain. This practice is designed to
Rubin Eitan, Monsonego Alon, Geifman Nophar   +2 more
doaj   +4 more sources

The Gene Ontology knowledgebase in 2026. [PDF]

Nucleic Acids Res
Abstract The Gene Ontology (GO) knowledgebase (https://geneontology.org) is a comprehensive resource describing the functions of genes. The GO knowledgebase is regularly updated and improved. We describe here the major updates that have been made in the past 3 years.
Gene Ontology Consortium .
europepmc   +4 more sources

Exploring autophagy with Gene Ontology [PDF]

Autophagy, 2018
Autophagy is a fundamental cellular process that is well conserved among eukaryotes. It is one of the strategies that cells use to catabolize substances in a controlled way. Autophagy is used for recycling cellular components, responding to cellular stresses and ridding cells of foreign material.
David Hill, Hélène Plun-Favreau, Paola Roncaglia   +2 more
exaly   +6 more sources

A review on Gene Ontology evaluations. [PDF]

Database (Oxford)
Abstract The analysis of the large and heterogeneous datasets that characterize modern biology demands systems capable of representing biological knowledge in a formal, standardized manner. The most widely used structured vocabulary in molecular biology and biomedicine is the Gene Ontology (GO).
Pitarch B, Chagoyen M, Ranea JAG, Pazos F.   +3 more
europepmc   +4 more sources

Capturing heart valve development with Gene Ontology [PDF]

Frontiers in Genetics, 2023
Introduction: The normal development of all heart valves requires highly coordinated signaling pathways and downstream mediators. While genomic variants can be responsible for congenital valve disease, environmental factors can also play a role. Later in
Saadullah H. Ahmed, Alexander T. Deng, Rachael P. Huntley, Nancy H. Campbell, Ruth C. Lovering   +4 more
doaj   +2 more sources

From Plant Ontology to Gene Ontology and back

Current Plant Biology, 2018
Our recent goal for the Plant Ontology (PO) is to have it integrated with the Gene Ontology (GO). The simplest aspect of this is to link morphological and anatomical images of structures for PO terms with genes involved in the development of those ...
Dennis Stevenson, Cecilia Zumajo-Cardona
doaj   +3 more sources