Results 101 to 110 of about 1,399 (186)

Biocuration in the structure–function linkage database: the anatomy of a superfamily [PDF]

, 2017
With ever-increasing amounts of sequence data available in both the primary literature and sequence repositories, there is a bottleneck in annotating molecular function to a sequence. This article describes the biocuration process and methods used in the
David Mischel, Ferrin, Thomas E, Gemma L. Holliday, Mischel, David, Hicks, Michael A, Brown, Shoshana D, Akiva, Eyal, Pegg, Scott C-H, Elaine C. Meng, Thomas E. Ferrin, Scott C.-H. Pegg, John H. Morris, Patricia C. Babbitt, Babbitt, Patricia C, Meng, Elaine C, Michael A. Hicks, Shoshana D. Brown, Eyal Akiva, Holliday, Gemma L, Morris, John H, Huang, Conrad C, Conrad C. Huang   +21 more
core   +1 more source

Improving biocuration of microRNAs in diseases: a case study in idiopathic pulmonary fibrosis [PDF]

, 2017
MicroRNAs (miRNAs) are small and non-coding RNA molecules that inhibit gene expression posttranscriptionally. They play important roles in several biological processes, and in recent years there has been an interest in studying how they are related to ...
Balderas-Martínez, Yalbi Itzel, Annie Pardo, Yalbi Itzel Balderas-Martínez, Hilda Solano-Lira, Julio Collado-Vides, Collado-Vides, Julio, Gabriela Contreras, Pardo, Annie, Solano-Lira, Hilda, Mishael Sánchez-Pérez, Contreras, Gabriela, Rinaldi, Fabio; https://orcid.org/, Fabio Rinaldi, Moisés Selman, Sánchez-Pérez, Mishael, Selman, Moisés   +15 more
core   +1 more source

Genomic repeats, misassembly and reannotation: a case study with long-read resequencing of Porphyromonas gingivalis reference strains

BMC Genomics, 2018
Background Without knowledge of their genomic sequences, it is impossible to make functional models of the bacteria that make up human and animal microbiota.
Luis Acuña-Amador, Aline Primot, Edouard Cadieu, Alain Roulet, Frédérique Barloy-Hubler   +4 more
doaj   +1 more source

Biocuration on the Bund

, 2018
<em> GigaScience are regular attendees of the International Biocuration Conference, and you may have read our write-ups ups going back to 2012 edition.&nbsp;This year Biocuration is back behind the bamboo curtain, with the 11th conference held in the Crowne Plaza Hotel Shanghai from April 8th-11th and hosted by Fudan University.
openaire   +1 more source

Knowledge engineering tools for reasoning with scientific observations and interpretations: a neural connectivity use case

BMC Bioinformatics, 2011
Background We address the goal of curating observations from published experiments in a generalizable form; reasoning over these observations to generate interpretations and then querying this interpreted knowledge to supply the supporting evidence.
Bota Mihail, Hovy Eduard H, Ramakrishnan Cartic, Russ Thomas A, Burns Gully APC   +4 more
doaj   +1 more source

An Ontology for formal representation of Drug Drug Interaction Knowledge [PDF]

, 2013
The poster at: The Sixth International Biocuration Conference (Biocuration 2013), took at April 7–10, 2013 in Churchill College, Cambridge, UK. The event web site in: http://www.ebi.ac.uk/biocuration2013/content/homeOntologies are useful tools in ...
Martínez Fernández, Paloma, Herrero Zazo, María, Segura-Bedmar, Isabel, Segura Bedmar, Isabel, Martínez, Paloma, Herrero Zazo, María   +5 more
core  

Textpresso Central: a customizable platform for searching, text mining, viewing, and curating biomedical literature

BMC Bioinformatics, 2018
Background The biomedical literature continues to grow at a rapid pace, making the challenge of knowledge retrieval and extraction ever greater. Tools that provide a means to search and mine the full text of literature thus represent an important way by ...
H.-M. Müller, K. M. Van Auken, Y. Li, P. W. Sternberg   +3 more
doaj   +1 more source

BI-LAVA: Biocuration with Hierarchical Image Labeling through Active Learning and Visual Analysis

, 2023
In the biomedical domain, taxonomies organize the acquisition modalities of scientific images in hierarchical structures. Such taxonomies leverage large sets of correct image labels and provide essential information about the importance of a scientific ...
Berrios, William, Wentzel, Andrew, Marai, G. Elisabeta, Trelles, Juan   +3 more
core  

The future of biocuration [PDF]

Nature, 2008
Doug Howe, Maria Costanzo, Petra Fey, Takashi Gojobori, Linda Hannick, Winston Hide, David P. Hill, Renate Kania, Mary Schaeffer, Susan St Pierre, Simon Twigger, Owen White, Seung Yon Rhee   +12 more
openaire   +1 more source

Dynamic Retrieval Augmented Generation of Ontologies using Artificial Intelligence (DRAGON-AI)

Journal of Biomedical Semantics
Background Ontologies are fundamental components of informatics infrastructure in domains such as biomedical, environmental, and food sciences, representing consensus knowledge in an accurate and computable form.
Sabrina Toro, Anna V. Anagnostopoulos, Susan M. Bello, Kai Blumberg, Rhiannon Cameron, Leigh Carmody, Alexander D. Diehl, Damion M. Dooley, William D. Duncan, Petra Fey, Pascale Gaudet, Nomi L. Harris, Marcin P. Joachimiak, Leila Kiani, Tiago Lubiana, Monica C. Munoz-Torres, Shawn O‘Neil, David Osumi-Sutherland, Aleix Puig-Barbe, Justin T. Reese, Leonore Reiser, Sofia MC. Robb, Troy Ruemping, James Seager, Eric Sid, Ray Stefancsik, Magalie Weber, Valerie Wood, Melissa A. Haendel, Christopher J. Mungall   +29 more
doaj   +1 more source