Results 71 to 80 of about 1,399 (186)

Biocuration Careers Workshop

, 2022
Based on the results from the 2020-2021 ISB survey, Biocurators contribute to a wide range of scholarly outputs other than traditional ones such as manuscripts, presentations, and grant funding. Furthermore, biocurators play leadership roles in various capacities that enhance the research process.
Vasilevsky, Nicole, Hosseini, Mohammad, Holmes, Kristi, Tuli, Mary Ann, Vita, Randi   +4 more
openaire   +2 more sources

A community of biocurators

Nature Precedings, 2010
AbstractBiocuration is a difficult mission: biological data is highly heterogeneous, and there are few areas where guidelines for data preservation and exchange exist. This has hampered the speed, quantity and diversity of data possible to capture.
openaire   +1 more source

Delving into Molecular Pathways: Analyzing the Mechanisms of Action of Monoclonal Antibodies Integrated in IMGT/mAb-DB for Myasthenia Gravis

Vaccines, 2023
Background: Myasthenia Gravis (MG) is a rare autoimmune disease presenting with auto-antibodies that affect the neuromuscular junction. In addition to symptomatic treatment options, novel therapeutics include monoclonal antibodies (mAbs).
Rebecca Golfinopoulou, Véronique Giudicelli, Taciana Manso, Sofia Kossida   +3 more
doaj   +1 more source

Visualizing and analyzing 3D biomolecular structures using Mol* at RCSB.org: Influenza A H5N1 virus proteome case study

Protein Science, Volume 34, Issue 4, April 2025.
Abstract The easiest and often most useful way to work with experimentally determined or computationally predicted structures of biomolecules is by viewing their three‐dimensional (3D) shapes using a molecular visualization tool. Mol* was collaboratively developed by RCSB Protein Data Bank (RCSB PDB, RCSB.org) and Protein Data Bank in Europe (PDBe ...
Sebastian Bittrich, Alexander S. Rose, David Sehnal, Jose M. Duarte, Yana Rose, Joan Segura, Dennis W. Piehl, Brinda Vallat, Chenghua Shao, Charmi Bhikadiya, Jesse Liang, Mark Ma, David S. Goodsell, Stephen K. Burley, Shuchismita Dutta   +14 more
wiley   +1 more source

The Biocurator: Connecting and Enhancing Scientific Data

PLoS Computational Biology, 2006
From Impressionism and Pop Art to phosphorylation sites and interacting atom pairs, the realm of curation has been expanded. The recent growth of bioinformatics, driven by exponentially growing data, advanced computing techniques, and increased funding from private and governmental organizations, has created the need for novel strategies to adequately ...
Nima Salimi, Randi Vita
openaire   +4 more sources

Representation of non-coding RNA-mediated regulation of gene expression using the Gene Ontology

RNA Biology
Regulatory non-coding RNAs (ncRNAs) are increasingly recognized as integral to the control of biological processes. This is often through the targeted regulation of mRNA expression, but this is by no means the only mechanism through which regulatory ...
Giulia Antonazzo, Pascale Gaudet, Ruth C. Lovering, Helen Attrill   +3 more
doaj   +1 more source

Automated assessment of biological database assertions using the scientific literature

BMC Bioinformatics, 2019
Background The large biological databases such as GenBank contain vast numbers of records, the content of which is substantively based on external resources, including published literature.
Mohamed Reda Bouadjenek, Justin Zobel, Karin Verspoor   +2 more
doaj   +1 more source

community-biocuration/cacao-annotations-analysis: CACAO annotation data 2010-2018

, 2021
Code and data used to generate the figures found in CACAO paper preprint at https://www.biorxiv.org/content/10.1101/2021.04.30 ...
jrr-cpt, Curtis Ross
core   +1 more source

A FAIR-Based Approach to Enhancing the Discovery and Re-Use of Transcriptomic Data Assets for Nuclear Receptor Signaling Pathways

Data Science Journal, 2017
Public transcriptomic assets in the nuclear receptor (NR) signaling field hold considerable collective potential for exposing underappreciated aspects of NR regulation of gene expression.
Scott A. Ochsner, Yolanda F. Darlington, Apollo McOwiti, Wasula H. Kankanamge, Alexey Naumov, Lauren B. Becnel, Neil J. McKenna   +6 more
doaj   +1 more source

TrialSieve: A Comprehensive Biomedical Information Extraction Framework for PICO, Meta-Analysis, and Drug Repurposing

Bioengineering
This work introduces TrialSieve, a novel framework for biomedical information extraction that enhances clinical meta-analysis and drug repurposing. By extending traditional PICO (Patient, Intervention, Comparison, Outcome) methodologies, TrialSieve ...
David Kartchner, Haydn Turner, Christophe Ye, Irfan Al-Hussaini, Batuhan Nursal, Albert J. B. Lee, Jennifer Deng, Courtney Curtis, Hannah Cho, Eva L. Duvaris, Coral Jackson, Catherine E. Shanks, Sarah Y. Tan, Selvi Ramalingam, Cassie S. Mitchell   +14 more
doaj   +1 more source