Results 71 to 80 of about 620 (141)

CardioTF, a database of deconstructing transcriptional circuits in the heart system [PDF]

open access: yesPeerJ, 2016
Background: Information on cardiovascular gene transcription is fragmented and far behind the present requirements of the systems biology field. To create a comprehensive source of data for cardiovascular gene regulation and to facilitate a deeper ...
Yisong Zhen
doaj   +2 more sources

The Biocurator: Connecting and Enhancing Scientific Data

open access: yesPLoS Computational Biology, 2006
From Impressionism and Pop Art to phosphorylation sites and interacting atom pairs, the realm of curation has been expanded. The recent growth of bioinformatics, driven by exponentially growing data, advanced computing techniques, and increased funding from private and governmental organizations, has created the need for novel strategies to adequately ...
Nima Salimi, Randi Vita
openaire   +4 more sources

Text-mining-assisted biocuration workflows in Argo [PDF]

open access: yesDatabase, 2014
Les activités de biocuration ont été largement classées dans la sélection des documents pertinents, l'annotation des concepts biologiques d'intérêt et l'identification des interactions entre les concepts. Il a été démontré que l'exploration de texte avait le potentiel de réduire considérablement l'effort des biocurateurs dans les trois activités, et ...
Rafał Rak   +4 more
openaire   +4 more sources

Mechanisms of action of monoclonal antibodies in oncology integrated in IMGT/mAb-DB

open access: yesFrontiers in Immunology, 2023
BackgroundCancer cells activate different immune checkpoint (IC) pathways in order to evade immunosurveillance. Immunotherapies involving ICs either block or stimulate these pathways and enhance the efficiency of the immune system to recognize and attack
Taciana Manso   +5 more
doaj   +1 more source

Integrating text mining into the MGI biocuration workflow [PDF]

open access: yesDatabase, 2009
AbstractA major challenge for the development of resources for functional and comparative genomics is the extraction of data from the biomedical literature. Although text retrieval and extraction for biological data is an active research field, few applications have been integrated into production literature curation systems such as those of the model ...
Karen G. Dowell   +4 more
openaire   +4 more sources

Changes in Scholarly Communication and the Potential Impact on Biocuration [PDF]

open access: yes, 2009
Open access in particular and changes in on-line scholarship have the potential to impact biocuration which often involves translating information currently read in papers to knowledge that is found in a variety of biological resources.
Philip Bourne
core   +1 more source

Databases and bioinformatics tools for rice research

open access: yesCurrent Plant Biology, 2016
Rice is one of the most important agricultural crop in the world and widely studied model plant. The completion of whole genome sequence of rice (Oryza sativa) and high-throughput experimental platforms have led to the generation of the tremendous amount
Priyanka Garg, Pankaj Jaiswal
doaj   +1 more source

TrialSieve: A Comprehensive Biomedical Information Extraction Framework for PICO, Meta-Analysis, and Drug Repurposing

open access: yesBioengineering
This work introduces TrialSieve, a novel framework for biomedical information extraction that enhances clinical meta-analysis and drug repurposing. By extending traditional PICO (Patient, Intervention, Comparison, Outcome) methodologies, TrialSieve ...
David Kartchner   +14 more
doaj   +1 more source

Biocuration of functional annotation at the European nucleotide archive [PDF]

open access: yesNucleic Acids Research, 2015
The European Nucleotide Archive (ENA; http://www.ebi.ac.uk/ena) is a repository for the submission, maintenance and presentation of nucleotide sequence data and related sample and experimental information. In this article we report on ENA in 2015 regarding general activity, notable published data sets and major achievements. This is followed by a focus
Richard Gibson   +20 more
openaire   +3 more sources

Representation of non-coding RNA-mediated regulation of gene expression using the Gene Ontology

open access: yesRNA Biology
Regulatory non-coding RNAs (ncRNAs) are increasingly recognized as integral to the control of biological processes. This is often through the targeted regulation of mRNA expression, but this is by no means the only mechanism through which regulatory ...
Giulia Antonazzo   +3 more
doaj   +1 more source

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