Results 61 to 70 of about 620 (141)

Delving into Molecular Pathways: Analyzing the Mechanisms of Action of Monoclonal Antibodies Integrated in IMGT/mAb-DB for Myasthenia Gravis

Vaccines, 2023
Background: Myasthenia Gravis (MG) is a rare autoimmune disease presenting with auto-antibodies that affect the neuromuscular junction. In addition to symptomatic treatment options, novel therapeutics include monoclonal antibodies (mAbs).
Rebecca Golfinopoulou, Véronique Giudicelli, Taciana Manso, Sofia Kossida   +3 more
doaj   +1 more source

Protein Data Bank (PDB) Archive: a new architecture (beta) for scalable, PDBx/mmCIF‐based data distribution

Acta Crystallographica Section D, Volume 82, Issue 8, Page 982-989, August 2026.
wwPDB has extended PDB IDs to 12 characters with a prefix `pdb_' followed by eight alphanumeric characters in lower case (for example pdb_1000axyz). A beta version of the PDB Archive (https://files‐beta.wwpdb.org), with extended PDB IDs and an improved directory structure, is now available to help communities adopt extended PDB IDs and the PDBx/mmCIF ...
Zukang Feng, Balakumaran Balasubramaniyan, Gert-Jan Bekker, Jose M. Duarte, Vladimir Guranovic, Jeremy Henry, Sreenath S. Nair, Ezra Peisach, Dennis W. Piehl, Aditya Pingale, James Smith, Brinda Vallat, Reiko Yamashita, Arthur Zalevsky, Kyle Morris, Jeff Hoch, Genji Kurisu, Sameer Velankar, Stephen K. Burley, Jasmine Y. Young   +19 more
wiley   +1 more source

Biocuration at the Saccharomyces genome database [PDF]

genesis, 2015
SummarySaccharomyces Genome Database is an online resource dedicated to managing information about the biology and genetics of the model organism, yeast (Saccharomyces cerevisiae). This information is derived primarily from scientific publications through a process of human curation that involves manual extraction of data and their organization into a ...
Marek S, Skrzypek, Robert S, Nash
openaire   +2 more sources

International Society for Biocuration response to NIH RFI on Proposed Provisions for a Draft Data Management and Sharing Policy for NIH Funded or Supported Research

, 2018
A response to the National Institutes of Health (NIH) request for information (RFI) on proposed provisions for a draft data management and sharing policy for NIH funded or supported research (https://osp.od.nih.gov/provisions-data-managment-sharing ...
International Society for Biocuration (8149653), International Society for Biocuration   +1 more
core   +1 more source

Automated assessment of biological database assertions using the scientific literature

BMC Bioinformatics, 2019
Background The large biological databases such as GenBank contain vast numbers of records, the content of which is substantively based on external resources, including published literature.
Mohamed Reda Bouadjenek, Justin Zobel, Karin Verspoor   +2 more
doaj   +1 more source

PDBe tools for an in‐depth analysis of small molecules in the Protein Data Bank

Protein Science, Volume 34, Issue 4, April 2025.
Abstract The Protein Data Bank (PDB) is the primary global repository for experimentally determined 3D structures of biological macromolecules and their complexes with ligands, proteins, and nucleic acids. PDB contains over 47,000 unique small molecules bound to the macromolecules.
Preeti Choudhary, Ibrahim Roshan Kunnakkattu, Sreenath Nair, Dare Kayode Lawal, Ivanna Pidruchna, Marcelo Querino Lima Afonso, Jennifer R. Fleming, Sameer Velankar   +7 more
wiley   +1 more source

Digital BioCuration: A Question of Balance [PDF]

Nature Precedings, 2009
AbstractCuration of biomedical data has come to encompass a broad range of activities and considerations, which include the building of digital archives, making decisions on the relative value and longevity of one dataset vs another, editing data records manually, performing or assessing computational processes over very large sets of data, and ...
James Ostell, James Ostell
openaire   +2 more sources

Visualizing and analyzing 3D biomolecular structures using Mol* at RCSB.org: Influenza A H5N1 virus proteome case study

Protein Science, Volume 34, Issue 4, April 2025.
Abstract The easiest and often most useful way to work with experimentally determined or computationally predicted structures of biomolecules is by viewing their three‐dimensional (3D) shapes using a molecular visualization tool. Mol* was collaboratively developed by RCSB Protein Data Bank (RCSB PDB, RCSB.org) and Protein Data Bank in Europe (PDBe ...
Sebastian Bittrich, Alexander S. Rose, David Sehnal, Jose M. Duarte, Yana Rose, Joan Segura, Dennis W. Piehl, Brinda Vallat, Chenghua Shao, Charmi Bhikadiya, Jesse Liang, Mark Ma, David S. Goodsell, Stephen K. Burley, Shuchismita Dutta   +14 more
wiley   +1 more source

Genomic Standards Consortium tools for genomic data biocuration - 2023 update.

, 2023
Presentation at the 16th International Biocuration Confernece, April 2023, Padova, Italy.
Lynn Schriml (4532953), Christopher Hunter (15313922)   +1 more
core   +1 more source

A FAIR-Based Approach to Enhancing the Discovery and Re-Use of Transcriptomic Data Assets for Nuclear Receptor Signaling Pathways

Data Science Journal, 2017
Public transcriptomic assets in the nuclear receptor (NR) signaling field hold considerable collective potential for exposing underappreciated aspects of NR regulation of gene expression.
Scott A. Ochsner, Yolanda F. Darlington, Apollo McOwiti, Wasula H. Kankanamge, Alexey Naumov, Lauren B. Becnel, Neil J. McKenna   +6 more
doaj   +1 more source