Lignin is one of the most abundant aromatic biopolymers and a major component of plant cell walls. It occurs via oxidative coupling of monolignols, which are synthesized from the phenylpropanoid pathway. Lignin is the primary material responsible for biomass recalcitrance, has almost no industrial utility, and cannot be simply removed from growing ...
Eudes, Aymerick+3 more
openaire +4 more sources
Three-dimensional (3D) tumor models generated in vitro using methods of tissue engineering are just starting to show potential for predictive studies of therapeutic targets and screening of anticancer drugs. By mimicking some of the key features of the in vivo tumor environment, these models allow us to grow physiologically relevant tumors and study ...
Aranzazu, Villasante+1 more
openaire +2 more sources
Maturation trajectories of cortical resting-state networks depend on the mediating frequency band [PDF]
The functional significance of resting state networks and their abnormal manifestations in psychiatric disorders are firmly established, as is the importance of the cortical rhythms in mediating these networks. Resting state networks are known to undergo
Bekhti, Yousra+16 more
core +1 more source
Nootropics use in the workplace. Psychiatric and ethical aftermath towards the new frontier of bioengineering [PDF]
OBJECTIVE: The authors have sought to expound upon and shed a light on the rise of nootropics, which have gradually taken on a more and more relevant role in workplaces and academic settings.
Bersani, G+5 more
core +1 more source
Kinetic Modeling and Numerical Simulation as Tools to Scale Microalgae Cell Membrane Permeabilization by Means of Pulsed Electric Fields (PEF) From Lab to Pilot Plants [PDF]
Pulsed Electric Fields (PEF) is a promising technology for the gentle and energy efficient disruption of microalgae cells such as Chlorella vulgaris.
Knappert, Justus+2 more
core +1 more source
The Current Use of Stem Cells in Bladder Tissue Regeneration and Bioengineering. [PDF]
Many pathological processes including neurogenic bladder and malignancy necessitate bladder reconstruction, which is currently performed using intestinal tissue. The use of intestinal tissue, however, subjects patients to metabolic abnormalities, bladder
Chan, Yvonne Y+3 more
core +2 more sources
Gradient matching methods for computational inference in mechanistic models for systems biology: a review and comparative analysis [PDF]
Parameter inference in mathematical models of biological pathways, expressed as coupled ordinary differential equations (ODEs), is a challenging problem in contemporary systems biology.
Husmeier, Dirk, Macdonald, Benn
core +10 more sources
Bioengineering models of cell signaling [PDF]
Strategies for rationally manipulating cell behavior in cell-based technologies and molecular therapeutics and understanding effects of environmental agents on physiological systems may be derived from a mechanistic understanding of underlying signaling ...
Asthagiri, Anand R.+1 more
core +1 more source
Computational Simulations for Aortic Coarctation: Representative Results From a Sampling of Patients [PDF]
Treatments for coarctation of the aorta (CoA) can alleviate blood pressure (BP) gradients(D), but long-term morbidity still exists that can be explained by altered indices of hemodynamics and biomechanics.
Chan, Frandics P+8 more
core +4 more sources
Hybrid bioprinting of chondrogenically induced human mesenchymal stem cell spheroids [PDF]
To date, the treatment of articular cartilage lesions remains challenging. A promising strategy for the development of new regenerative therapies is hybrid bioprinting, combining the principles of developmental biology, biomaterial science, and 3D ...
Asadian, Mahtab+8 more
core +2 more sources