Results 31 to 40 of about 376,139 (290)

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Crop Bioengineering: Enormous Potential for Catalyzing International Development [PDF]

, 2009
[Excerpt] Bioengineering provides unique and dramatic opportunities for crop improvement. It can be used to develop crop varieties that would otherwise be unavailable and can facilitate much faster and more precise ways of developing improved varieties ...
Gregory, Peter, Kowalski, Stanley P.
core   +1 more source

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Automatic Segmentation of Exudates in Ocular Images using Ensembles of Aperture Filters and Logistic Regression [PDF]

, 2013
Hard and soft exudates are the main signs of diabetic macular edema (DME). The segmentation of both kinds of exudates generates valuable information not only for the diagnosis of DME, but also for treatment, which helps to avoid vision loss and blindness.
Ballarin, Virginia Laura, Benalcazar Palacios, Marco Enrique, Brun, Marcel   +2 more
core   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Building a Bird: Musculoskeletal Modeling and Simulation of Wing-Assisted Incline Running during Avian Ontogeny [PDF]

, 2018
Flapping flight is the most power-demanding mode of locomotion, associated with a suite of anatomical specializations in extant adult birds. In contrast, many developing birds use their forelimbs to negotiate environments long before acquiring “flight ...
Ashley M. Heers, Ashley M. Heers, Jeffery W. Rankin, Jeffery W. Rankin, John R. Hutchinson   +4 more
core   +2 more sources

Bioengineering [PDF]

Bioengineered, 2012
While the bacteriocin Nisin has been employed by the food industry for 60 y, it remains the only bacteriocin to be extensively employed as a food preservative. This is despite the fact that the activity of Nisin against several food spoilage and pathogenic bacteria is poor and the availability of many other bacteriocins with significant potential in ...
openaire   +2 more sources

Bioengineering horizon scan 2020

eLife, 2020
Horizon scanning is intended to identify the opportunities and threats associated with technological, regulatory and social change. In 2017 some of the present authors conducted a horizon scan for bioengineering (Wintle et al., 2017). Here we report the results of a new horizon scan that is based on inputs from a larger and more international group of ...
Christopher Simuntala, Anna Roessing, Appolinaire Djikeng, Piers Millett, Malcolm Dando, Clarissa Rios-Rojas, Philip Shapira, Philip Shapira, Philip Shapira, Nicola J. Patron, Kelly Hills, Deborah Scott, Cassidy Nelson, William J. Sutherland, Catherine Rhodes, Rainer Breitling, Lalitha S Sundaram, Bonnie C. Wintle, Megan J. Palmer, Wibool Piyawattanametha, Rocco Casagrande, Laura Adam, Anne Osbourn, Luke Kemp, Edward Perello, Eriko Takano, Robert Dj Smith, Alemka Markotić, Alemka Markotić, Alemka Markotić, Richard Hammond, Gwyn Uttmark, Christian R. Boehm, Vanessa Restrepo-Schild, Nicholas Evans, Johnathan A. Napier, Lauren A Holt, Seán S. ÓhÉigeartaigh, Nadia Batool Zahra, Todd Kuiken   +39 more
openaire   +8 more sources

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

FEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source