Results 31 to 40 of about 102,774 (287)
STAR Protocols, 2022 Summary: Liquid metals are increasingly applied in drug delivery, in vivo imaging, and biosensing. Herein, we describe a surface modification strategy, where cell membrane is introduced to encapsulate gallium (Ga) particles.
Xuelin Wang +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Advanced Strategies for Production of Natural Products in Yeast
iScience, 2020 Natural products account for more than 50% of all small-molecule pharmaceutical agents currently in clinical use. However, low availability often becomes problematic when a bioactive natural product is promising to become a pharmaceutical or leading ...
Ruibing Chen +3 more
doaj +1 more source
, 2020 Current Developments in Biotechnology and Bioengineering: Advanced Membrane Separation Processes for Sustainable Water and Wastewater Management - Case Studies and Sustainability Analysis gives an up-to-date review and research developments of MBR ...
Mannina G. +4 more
core +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Current Developments in Biotechnology and Bioengineering : Emerging Organic Micro-pollutants
, 2020 International audienceCurrent Developments in Biotechnology and Bioengineering: Emerging Organic Micropollutants summarizes the current knowledge of emerging organic micropollutants in wastewater and the possibilities of their removal/elimination.
Tiagi, Rajeshwar, Dayal +4 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Protocol to generate PDMS topographical patterns for hiPSC-derived or rat primary neuronal cultures
STAR ProtocolsSummary: Soft lithography is a promising technique to fabricate tailored substrates on polydimethylsiloxane (PDMS) casts. Here, we present a protocol to generate PDMS topographical patterns for neuronal networks in vitro.
Anna-Christina Haeb +2 more
doaj +1 more source
Chromosomal integration of complex DNA constructs using CRAGE and CRAGE-Duet systems
STAR Protocols, 2022 Summary: Our recent development of the CRAGE (chassis-independent recombinase-assisted genome engineering) system enables single-step integration of large, complex DNA constructs directly into bacteria genomes across multiple phyla.
Zhiying Zhao +2 more
doaj +1 more source
The Institute for Biotechnology and Bioengineering (IBB) [PDF]
, 2014 The Laboratório Associado Institute for Biotechnology and Bioengineering (IBB) is a research unit aiming to be a strategic infrastructure for the development of the Portuguese R&D and innovation policies in the areas of Biotechnology ...
Cabral, J. M. S. +6 more
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