Results 41 to 50 of about 102,774 (287)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Genome editing in Penicillium funiculosum using in vitro assembled CRISPR-Cas9 ribonucleoprotein complexes

STAR Protocols, 2022
Summary: The plasmid-free CRISPR-Cas9-based genome editing in fungi is a precise and time-saving approach. Here, we present a detailed protocol for genetic manipulation in Penicillium funiculosum, which includes design and synthesis of sgRNA, high ...
Tulika Sinha, Syed Shams Yazdani
doaj   +1 more source

The Institute for Biotechnology and Bioengineering (IBB) [PDF]

, 2009
The Laboratório Associado Institute for Biotechnology and Bioengineering (IBB) is a research unit aiming to be a strategic infrastructure for the development of the Portuguese R&D and innovation policies in the areas of Biotechnology, Bioengineering ...
Cabral, J. M. S., Ferreira, Eugénio C., Ferreira, Guilherme, Pinto, Henrique Guedes, Reis, R. L., Martel, Paulo, Mota, M.   +6 more
core  

Current Developments in Biotechnology and Bioengineering : Advances in Bioprocess Engineering

, 2022
International audienceAdvances in Bioprocess Engineering, the latest release in the Current Developments in Biotechnology and Bioengineering series, provides a comprehensive overview of bioprocess systems, kinetics, bioreactor design, batch and ...
Taherzadeh, Mohammad, J, Sirohi, Ranjna, Larroche, Christian, Pandey, Ashok   +3 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

High-Efficiency Multi-site Genomic Editing of Pseudomonas putida through Thermoinducible ssDNA Recombineering

iScience, 2020
Summary: Application of single-stranded DNA recombineering for genome editing of species other than enterobacteria is limited by the efficiency of the recombinase and the action of endogenous mismatch repair (MMR) systems.
Tomas Aparicio, Akos Nyerges, Esteban Martínez-García, Víctor de Lorenzo   +3 more
doaj   +1 more source

Construction of a high-NFOM multiphoton microscope with large-angle resonant raster scanning

STAR Protocols, 2022
Summary: A resonant-scanning multiphoton optical microscope (MPM) with a millimeter-scale field-of-view (FOV) often encounters a poor Nyquist figure-of-merit (NFOM), leading to an aliasing effect owing to limited effective voxel-sampling rate.
Bhaskar Jyoti Borah, Chi-Kuang Sun
doaj   +1 more source

Highlights from the ECB11: building bridges between biosciences and bioengineering

, 2004
von Stockar U, Pühler A. Highlights from the ECB11: building bridges between biosciences and bioengineering. JOURNAL OF BIOTECHNOLOGY.
von Stockar, U, von Stockar, Urs, Puehler, Alfred, Pühler, Alfred ; https://orcid.org/   +3 more
core   +1 more source

Magnetic Force-Based Microfluidic Techniques for Cellular and Tissue Bioengineering [PDF]

, 2018
PubMed: 30619842Live cell manipulation is an important biotechnological tool for cellular and tissue level bioengineering applications due to its capacity for guiding cells for separation, isolation, concentration, and patterning.
H. Cumhur Tekin, Yaman, Sena, Tekin, H. Cumhur, Anıl İnevi, Müge, Sena Yaman, Muge Anil-Inevi, Engin Ozcivici, Özçivici, Engin, 1. Yaman, Sena, 3. Özçivici, Engin, 4. Tekin, Hüseyin Cumhur, Anil-Inevi, Muge, 2. Anıl İnevi, Müge   +12 more
core   +1 more source

Science communication in bioengineering and biotechnology: Active and collaborative learning project [PDF]

, 2021
In a society increasingly dependent on science and technology, the need to equip our students with the most varied digital and communication skills is crucial.
Peixoto, J. M., Vilaça, T., Pereira, M. Alcina, Rodrigues, Lígia, Pereira, M. Olívia, Vicente, A. A., Pereira, M. A., Azeredo, Joana, Peixoto, João M., Neves, P., Rodrigues, L. R., Henriques, Mariana, Vicente, António A., Pereira, Maria Olívia, Peixoto, L., Peixoto, Luciana, Neves, Patrícia, Vilaça, Tatiana   +17 more
core   +1 more source