Results 31 to 40 of about 335 (100)

Intermittent Hypoxia Mimicking Sleep Apnea Increases Passive Stiffness of Myocardial Extracellular Matrix. A Multiscale Study

Frontiers in Physiology, 2018
Background: Tissue hypoxia-reoxygenation characterizes obstructive sleep apnea (OSA), a very prevalent respiratory disease associated with increased cardiovascular morbidity and mortality.
Núria Farré, Núria Farré, Núria Farré, Jorge Otero, Jorge Otero, Bryan Falcones, Bryan Falcones, Marta Torres, Marta Torres, Ignasi Jorba, Ignasi Jorba, David Gozal, Isaac Almendros, Isaac Almendros, Isaac Almendros, Ramon Farré, Ramon Farré, Ramon Farré, Daniel Navajas, Daniel Navajas, Daniel Navajas   +20 more
doaj   +1 more source

Involvement of Mechanical Cues in the Migration of Cajal-Retzius Cells in the Marginal Zone During Neocortical Development

Frontiers in Cell and Developmental Biology, 2022
Emerging evidence points to coordinated action of chemical and mechanical cues during brain development. At early stages of neocortical development, angiogenic factors and chemokines such as CXCL12, ephrins, and semaphorins assume crucial roles in ...
Ana López-Mengual, Ana López-Mengual, Ana López-Mengual, Ana López-Mengual, Miriam Segura-Feliu, Miriam Segura-Feliu, Miriam Segura-Feliu, Miriam Segura-Feliu, Raimon Sunyer, Héctor Sanz-Fraile, Jorge Otero, Jorge Otero, Francina Mesquida-Veny, Francina Mesquida-Veny, Francina Mesquida-Veny, Francina Mesquida-Veny, Vanessa Gil, Vanessa Gil, Vanessa Gil, Vanessa Gil, Arnau Hervera, Arnau Hervera, Arnau Hervera, Arnau Hervera, Isidre Ferrer, Isidre Ferrer, Isidre Ferrer, Jordi Soriano, Jordi Soriano, Xavier Trepat, Xavier Trepat, Xavier Trepat, Xavier Trepat, Ramon Farré, Ramon Farré, Ramon Farré, Daniel Navajas, Daniel Navajas, Daniel Navajas, José Antonio del Río, José Antonio del Río, José Antonio del Río, José Antonio del Río   +42 more
doaj   +1 more source

Passive Stiffness of Left Ventricular Myocardial Tissue Is Reduced by Ovariectomy in a Post-menopause Mouse Model

Frontiers in Physiology, 2018
Background: Heart failure (HF) – a very prevalent disease with high morbidity and mortality – usually presents with diastolic dysfunction. Although post-menopause women are at increased risk of HF and diastolic dysfunction, poor attention has been paid ...
Núria Farré, Núria Farré, Núria Farré, Ignasi Jorba, Ignasi Jorba, Marta Torres, Marta Torres, Bryan Falcones, Bryan Falcones, Julio Martí-Almor, Julio Martí-Almor, Ramon Farré, Ramon Farré, Ramon Farré, Isaac Almendros, Isaac Almendros, Isaac Almendros, Daniel Navajas, Daniel Navajas, Daniel Navajas   +19 more
doaj   +1 more source

Circulating exosomes and gut microbiome induced insulin resistance in mice exposed to intermittent hypoxia: Effects of physical activity

EBioMedicine, 2021
Background: Gut microbiota (GM) contribute to obesity and insulin resistance (IR). Obstructive sleep apnea (OSA), characterized by intermittent hypoxia (IH), promotes IR and alters GM.
Abdelnaby Khalyfa, Aaron Ericsson, Zhuanghong Qiao, Isaac Almendros, Ramon Farré, David Gozal   +5 more
doaj   +1 more source

Insights into the Interfacial Charge Transfer Dynamics in Semiconductor–Molecular Catalyst Assemblies for Photo–Induced CO2 Reduction

ChemElectroChem, Volume 11, Issue 11, June 3, 2024.
This mini–review describes recent examples of Semiconductor–Molecular catalyst hybrid systems in which complementary studies were performed relating interfacial photo–induced charge transfer measurements and their impact on photo and photoelectrochemical multi–redox CO2 reduction reactions.
Tamal Chatterjee, Beatriu Domingo‐Tafalla, Pablo Ballester, Emilio Palomares   +3 more
wiley   +1 more source

Nanoscale Operando Characterization of Electrolyte‐Gated Organic Field‐Effect Transistors Reveals Charge Transport Bottlenecks

Advanced Materials, Volume 36, Issue 13, March 28, 2024.
This study delves into the charge transport properties of electrolyte‐gated organic field‐effect transistors by employing in‐liquid scanning dielectric microscopy. By introducing a novel interpretation framework, the research achieves quantitative mapping of the local electric potential, facilitating a detailed assessment of charge transport ...
Shubham Tanwar, Ruben Millan‐Solsona, Sara Ruiz‐Molina, Marta Mas‐Torrent, Adrica Kyndiah, Gabriel Gomila   +5 more
wiley   +1 more source

Rationally designed azobenzene photoswitches for efficient two-photon neuronal excitation

Nature Communications, 2019
Two-photon absorption capacity of azobenzene photoswitches usually comes with a reduction in thermal stability. Here, the authors developed photoswitches with high two-photon sensitivity and enhanced cis isomer thermal lifetime for the control of ...
Gisela Cabré, Aida Garrido-Charles, Miquel Moreno, Miquel Bosch, Montserrat Porta-de-la-Riva, Michael Krieg, Marta Gascón-Moya, Núria Camarero, Ricard Gelabert, José M. Lluch, Félix Busqué, Jordi Hernando, Pau Gorostiza, Ramon Alibés   +13 more
doaj   +1 more source

Alzheimer’s Disease Mutant Mice Exhibit Reduced Brain Tissue Stiffness Compared to Wild-type Mice in both Normoxia and following Intermittent Hypoxia Mimicking Sleep Apnea

Frontiers in Neurology, 2018
BackgroundEvidence from patients and animal models suggests that obstructive sleep apnea (OSA) may increase the risk of Alzheimer’s disease (AD) and that AD is associated with reduced brain tissue stiffness.AimTo investigate whether intermittent hypoxia (
Maria José Menal, Ignasi Jorba, Ignasi Jorba, Marta Torres, Marta Torres, Josep M. Montserrat, Josep M. Montserrat, David Gozal, Anna Colell, Gerard Piñol-Ripoll, Daniel Navajas, Daniel Navajas, Daniel Navajas, Isaac Almendros, Isaac Almendros, Isaac Almendros, Ramon Farré, Ramon Farré, Ramon Farré   +18 more
doaj   +1 more source

ERS International Congress, Madrid, 2019: highlights from the Sleep and Clinical Physiology Assembly

ERJ Open Research, 2020
The 2019 European Respiratory Society (ERS) International Congress took place in Madrid, Spain, and served as a platform to find out the latest advances in respiratory diseases research. The research aims are to understand the physiology and consequences
Andrea Crespo, Sébastien Baillieul, Esther Marhuenda, Matteo Bradicich, Vasileios Andrianopoulos, Louvaris Zafeiris, Mathieu Marillier, Isaac Almendros   +7 more
doaj   +1 more source

Formation of an invasion-permissive matrix requires TGFβ/SNAIL1-regulated alternative splicing of fibronectin

Breast Cancer Research, 2023
Background As in most solid cancers, the emergence of cells with oncogenic mutations in the mammary epithelium alters the tissue homeostasis. Some soluble factors, such as TGFβ, potently modify the behavior of healthy stromal cells.
Héctor Franco-Valls, Elsa Tusquets-Uxó, Laura Sala, Maria Val, Raúl Peña, Alessandra Iaconcig, Álvaro Villarino, Martín Jiménez-Arriola, Pere Massó, Juan L. Trincado, Eduardo Eyras, Andrés F. Muro, Jorge Otero, Antonio García de Herreros, Josep Baulida   +14 more
doaj   +1 more source