Immunomodulatory role of vasoactive intestinal peptide and ghrelin in Oncorhynchus mykiss [PDF]
Heliyon, 2023 Neuropeptides are a group of peptides derived from precursor proteins synthesized in neuronal and nonneuronal cells. The classical functions of neuropeptides have been extensively studied in mammals, including neuromodulation in the central nervous ...
Carolina Muñoz-Flores +13 more
doaj +2 more sources
Co-Formulation of Recombinant Porcine IL-18 Enhances the Onset of Immune Response in a New Lawsonia intracellularis Vaccine [PDF]
Vaccines, 2023 Pig is one of the most consumed meats worldwide. One of the main conditions for pig production is Porcine Enteropathy caused by Lawsonia intracellularis.
Angela Hidalgo-Gajardo +13 more
doaj +2 more sources
First report of bovine viral diarrhea virus subgenotypes 1d and 1e in southern Chile [PDF]
Virology Journal, 2023 Bovine viral diarrhea virus (BVDV) affects cattle worldwide causing severe productive and economic loss. In this study, we investigated the subgenotypes of BVDV circulating in cattle samples from the Aysén region, an active cattle breeding area located ...
Florence Hugues +12 more
doaj +2 more sources
Development of New Potential Inhibitors of β1 Integrins through In Silico Methods—Screening and Computational Validation [PDF]
Life, 2022 Integrins are transmembrane receptors that play a critical role in many biological processes which can be therapeutically modulated using integrin blockers, such as peptidomimetic ligands.
Disraeli Vasconcelos +8 more
doaj +2 more sources
Safety and immunogenicity of a SARS-CoV-2 Gamma variant RBD-based protein adjuvanted vaccine used as booster in healthy adults [PDF]
Nature Communications, 2023 A Gamma Variant RBD-based aluminum hydroxide adjuvanted vaccine called ARVAC CG was selected for a first in human clinical trial. Healthy male and female participants (18-55 years old) with a complete COVID-19-primary vaccine scheme were assigned to ...
Karina A. Pasquevich +24 more
doaj +2 more sources
Assessment of a porcine circovirus type 2 vaccine prototype through anatomopathological analysis and its correlation with blood viral load [PDF]
Frontiers in Veterinary SciencePorcine circovirus type 2 (PCV2) is an endemic pathogen of global relevance, responsible for porcine circovirus-associated diseases (PCVAD). Consequently, vaccination against PCV2 is a standard practice in intensive swine production systems.
Fernanda Larenas-Muñoz +7 more
doaj +2 more sources
New insight into the biological activity of Salmo salar NK-lysin antimicrobial peptides [PDF]
Frontiers in ImmunologyNK-lysin is a potent antimicrobial peptide (AMP) with antimicrobial activity against bacteria, fungi, viruses, and parasites. NK-lysin is a type of granulysin, a member of the saposin-like proteins family first isolated from a pig’s small intestine.
Leonardo Ortega +22 more
doaj +2 more sources
A Gamma-adapted subunit vaccine induces broadly neutralizing antibodies against SARS-CoV-2 variants and protects mice from infection [PDF]
Nature CommunicationsIn the context of continuous emergence of SARS-CoV-2 variants of concern (VOCs), one strategy to prevent the severe outcomes of COVID-19 is developing safe and effective broad-spectrum vaccines.
Lorena M. Coria +33 more
doaj +2 more sources
Heterologous Booster with BNT162b2 Induced High Specific Antibody Levels in CoronaVac Vaccinees [PDF]
Vaccines, 2023 Immune responses after COVID-19 vaccination should be evaluated in different populations around the world. This study compared antibody responses induced by ChAdOx1 nCoV-19, CoronaVac, and BNT162b2 vaccines.
Letícia Carrijo Masson +10 more
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Vector competence of Culex mosquitoes (Diptera: Culicidae) in Zika virus transmission: an integrative review [PDF]
Revista Panamericana de Salud Pública, 2020 Objective. To identify studies on the competence of Culex mosquitoes as vectors for the transmission of Zika virus (ZIKV) around the globe. Methods. We performed an integrative review to identify relevant articles on specific experiments to determine ...
Sandro G. Viveiros-Rosa +2 more
doaj +2 more sources