Results 21 to 30 of about 590 (89)

Establecimiento de un protocolo de transformación transitoria y estable de Nicotiana tabacum mediada por Agrobacterium tumefaciens

Tecnología en Marcha, 2019
Actualmente las herramientas biotecnológicas como la ingeniería genética y la biología molecular se encuentran muy avanzadas, permitiendo el desarrollo de sistemas que se basan en el uso de células vegetales para la producción de proteínas recombinantes,
Laura Méndez-Muñoz, So a Campos-Delgado, Mariel Obando-Coronado, Giovanni Garro-Monge   +3 more
doaj   +1 more source

The Deleterious Effects of Shiga Toxin Type 2 Are Neutralized In Vitro by FabF8:Stx2 Recombinant Monoclonal Antibody

Toxins, 2021
Hemolytic Uremic Syndrome (HUS) associated with Shiga-toxigenic Escherichia coli (STEC) infections is the principal cause of acute renal injury in pediatric age groups.
Daniela Luz, Fernando D. Gómez, Raíssa L. Ferreira, Bruna S. Melo, Beatriz E. C. Guth, Wagner Quintilio, Ana Maria Moro, Agostina Presta, Flavia Sacerdoti, Cristina Ibarra, Gang Chen, Sachdev S. Sidhu, María Marta Amaral, Roxane M. F. Piazza   +13 more
doaj   +1 more source

Chronic Cholestatic Liver Disease Induced by Larval Ascariasis: Novel Insights Into Immune‐Mediated Pathogenesis and Hepatic Fibrosis in Mice

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Liver alterations induced by single infection (SI) or reinfection (RE) with 250 or 2500 Ascaris suum eggs in mice. Histological analysis shows inflammatory cell infiltration (eosinophils, lymphocytes, macrophages, and neutrophils), fibrotic areas, and bile duct proliferation in infected animals compared with uninfected controls.
Jorge Lucas Nascimento Souza, Chiara Cássia Oliveira Amorim, Ana Rafaela Antunes‐Porto, Fernanda Rezende Souza, Evelyn Ane Oliveira, Izabela da Silva Oliveira, Isabela de Brito Duval, Andressa Mariana Saldanha‐Elias, Marcelo Eduardo Cardozo, Ramayana Morais de Medeiros Brito, Luisa Mourão Dias Magalhães, Geovanni Dantas Cassali, Neima Briggs, Ricardo Toshio Fujiwara, Remo Castro Russo, Guilherme Grossi Lopes Cançado, Lilian Lacerda Bueno   +16 more
wiley   +1 more source

Genomic Insights Into Respiratory Syncytial Virus Circulation Patterns and Neutralization by Anti‐F Monoclonal Antibodies in Panama (2018–2024)

Influenza and Other Respiratory Viruses, Volume 19, Issue 10, October 2025.
ABSTRACT Background Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections and hospitalization in infants and children. Whole genome sequencing (WGS) plays a critical role in understanding the evolution and epidemiology of RSV.
Danilo Franco, Stephanie Goya, Alexander Martínez, Vicente Mas, Brechla Moreno, Elimelec Valdespino, Melissa Gaitán, Lisseth Sáenz, Claudia González, Ambar Moreno, Zeuz Capitan‐Barrios, Jean Paul Carrera, Sandra López‐Vergès, Juan Miguel Pascale, Yadira Moltó, Lourdes Moreno, Belmaris Rizo, Enrique Urriola, Teresa Delgado, María Iglesias‐Caballero, Inmaculada Casas, Suman R. Das, Juan Arbiza, Adriana Delfraro, Leyda Ábrego   +24 more
wiley   +1 more source

Biossegurança no desenvolvimento de vacinas biofármacos e kits de diagnóstico / Biosafety in the development of vaccines, biopharmaceuticals and diagnostic kits [PDF]

, 2020
O desenvolvimento e produção de imunobiológicos (vacinas, biofármacos e imunodiagnóstico), requer uma ampla gama de medidas de biossegurança para garantir a segurança de seus funcionários, do produto final e dos consumidores destes produtos.
Müller, Rodrigo, Senna, José Procópio Moreno   +1 more
core  

New insight into the biological activity of Salmo salar NK-lysin antimicrobial peptides

Frontiers in Immunology
NK-lysin is a potent antimicrobial peptide (AMP) with antimicrobial activity against bacteria, fungi, viruses, and parasites. NK-lysin is a type of granulysin, a member of the saposin-like proteins family first isolated from a pig’s small intestine.
Leonardo Ortega, Crisleri Carrera, Carolina Muñoz-Flores, Santiago Salazar, Milton F. Villegas, María F. Starck, Ariel Valenzuela, Niza Agurto, Raquel Montesino, Allisson Astuya, Natalie Parra, Ercilia T. Pérez, Ercilia T. Pérez, Natacha Santibáñez, Natacha Santibáñez, Alex Romero, Alex Romero, Pamela Ruíz, Emilio Lamazares, Fátima Reyes, Oliberto Sánchez, Jorge R. Toledo, Jannel Acosta   +22 more
doaj   +1 more source

Biotecnologia translacional: hemopressina e outros peptídeos intracelulares

Estudos Avançados, 2010
A biotecnologia é uma prática antiga, sendo utilizada desde o antigo Egito para a produção de pão e cerveja. No mundo contemporâneo, a biotecnologia tem sido utilizada de diversas formas, incluindo o tratamento de doenças.
Emer Suavinho Ferro
doaj   +1 more source

Opposite effects of systemic and local conditional CD11c+ myeloid cell depletion during bleomycin‐induced inflammation and fibrosis in mice

Immunity, Inflammation and Disease, Volume 12, Issue 11, November 2024.
Dendritic cells (DCs) and macrophages (MΦ) are key antigen‐presenting cells (APCs) that direct adaptive immunity. The role of CD11c+ myeloid cells in lung extracellular matrix (ECM) accumulation and pulmonary fibrosis is not well understood. Systemic depletion of CD11c+ cells confers protection against inflammation and fibrosis induced by bleomycin ...
Gabriel Augusto Oliveira Lopes, Braulio Henrique Freire Lima, Camila Simões Freitas, Andiara Cardoso Peixoto, Frederico Marianetti Soriani, Geovanni Dantas Cassali, Bernhard Ryffel, Mauro Martins Teixeira, Fabiana Simão Machado, Remo Castro Russo   +9 more
wiley   +1 more source

Escorpiones de Sonora, México y su potencial biotecnológico

Epistemus
Los escorpiones son arácnidos, fácilmente reconocibles por la presencia de una cola que termina en aguijón, así como de pinzas similares a las de crustáceos.
Carlos Roberto Hiriart Moreno, Jorge Jimenez Canale   +1 more
doaj   +1 more source

Structural Changes in Stx1 Engineering Monoclonal Antibody Improves Its Functionality as Diagnostic Tool for a Rapid Latex Agglutination Test

Antibodies, 2018
Stx1 toxin is one of the AB5 toxins of Shiga toxin-producing Escherichia coli (STEC) responsible for foodborne intoxication during outbreaks. The single-chain variable fragment (scFv) is the most common recombinant antibody format; it consists of both ...
Daniela Luz, Emerson A. Shiga, Gang Chen, Wagner Quintilio, Fernanda B. Andrade, Andrea Q. Maranhão, Bruna A. Caetano, Thaís Mitsunari, Míriam A. Silva, Letícia B. Rocha, Ana M. Moro, Sachdev S. Sidhu, Roxane M. F. Piazza   +12 more
doaj   +1 more source