Results 21 to 30 of about 1,601 (130)

Generation of a Chinese Hamster Ovary Cell Line Producing Recombinant Human Glucocerebrosidase

open access: yesBioMed Research International, Volume 2012, Issue 1, 2012., 2012
Impaired activity of the lysosomal enzyme glucocerebrosidase (GCR) results in the inherited metabolic disorder known as Gaucher disease. Current treatment consists of enzyme replacement therapy by administration of exogenous GCR. Although effective, it is exceptionally expensive, and patients worldwide have a limited access to this medicine. In Brazil,
Juliana Branco Novo   +7 more
wiley   +1 more source

Bulgarian Propolis Induces Analgesic and Anti-inflammatory Effects in Mice and Inhibits In Vitro Contraction of Airway Smooth Muscle

open access: yesJournal of Pharmacological Sciences, 2003
: Propolis is a bee product, which has long been used in folk medicine for the management of different diseases. In this study we evaluated the analgesic and anti-inflammatory effects of a standard ethanolic extract of Bulgarian propolis (Et-Blg) in mice
Niraldo Paulino   +6 more
doaj   +1 more source

Biofármacos usados para o tratamento de artrite reumatoide: uma revisão de literatura: Biopharmaceuticals used in the treatment of rheumatoid arthritis: a literature review [PDF]

open access: yes, 2022
A artrite reumatoide é uma doença inflamatória crônica de caráter autoimune que tem como principais alvos as articulações, podendo levar à destruição desses tecidos quando não tratada, o que pode resultar na diminuição dos movimentos e na qualidade de ...
de Oliveira Souza, Maurília   +2 more
core   +2 more sources

ESTRATÉGIAS PARA AUMENTAR A DISPONIBILIDADE DE PLASMA EXCEDENTE DO USO TRANSFUSIONAL

open access: yesHematology, Transfusion and Cell Therapy, 2023
Introdução: A Política Nacional de Sangue, Componentes e Hemoderivados, definida pela Lei 10.205/2001, tem como finalidade garantir a autossuficiência do país nesse setor. Para isso, ações do poder público devem acontecer de forma harmonizada em todos os
RG Bastos   +7 more
doaj   +1 more source

A UTILIZAÇÃO DO ANTI-CD3 BUTANTAN NO TRANSPLANTE RENAL

open access: yesBrazilian Journal of Transplantation, 2006
Objetivos: O anticorpo monoclonal anti-CD3 tem sido empregado na prevenção e tratamento de episódios de rejeição aguda em transplante de órgãos. Neste estudo retrospectivo, relatamos a experiência de três instituições brasileiras que utilizaram o ...
Francine Lemos   +13 more
doaj   +1 more source

Effects of Continuous Light (LD24:0) Modulate the Expression of Lysozyme, Mucin and Peripheral Blood Cells in Rainbow Trout

open access: yesFishes, 2022
Continuous photoperiod is extensively used in fish farming, to regulate the reproductive cycle, despite evidence suggesting that artificial photoperiods can act as a stressor and impair the immune system.
Ariel Valenzuela   +6 more
doaj   +1 more source

Establecimiento de un protocolo de transformación transitoria y estable de Nicotiana tabacum mediada por Agrobacterium tumefaciens

open access: yesTecnología en Marcha, 2019
Actualmente las herramientas biotecnológicas como la ingeniería genética y la biología molecular se encuentran muy avanzadas, permitiendo el desarrollo de sistemas que se basan en el uso de células vegetales para la producción de proteínas recombinantes,
Laura Méndez-Muñoz   +3 more
doaj   +1 more source

The Deleterious Effects of Shiga Toxin Type 2 Are Neutralized In Vitro by FabF8:Stx2 Recombinant Monoclonal Antibody

open access: yesToxins, 2021
Hemolytic Uremic Syndrome (HUS) associated with Shiga-toxigenic Escherichia coli (STEC) infections is the principal cause of acute renal injury in pediatric age groups.
Daniela Luz   +13 more
doaj   +1 more source

Opposite effects of systemic and local conditional CD11c+ myeloid cell depletion during bleomycin‐induced inflammation and fibrosis in mice

open access: yesImmunity, Inflammation and Disease, Volume 12, Issue 11, November 2024.
Dendritic cells (DCs) and macrophages (MΦ) are key antigen‐presenting cells (APCs) that direct adaptive immunity. The role of CD11c+ myeloid cells in lung extracellular matrix (ECM) accumulation and pulmonary fibrosis is not well understood. Systemic depletion of CD11c+ cells confers protection against inflammation and fibrosis induced by bleomycin ...
Gabriel Augusto Oliveira Lopes   +9 more
wiley   +1 more source

Amazônia: laboratório do mundo. [PDF]

open access: yes, 2014
bitstream/item/103588/1/7256 ...
ALVES, R. N. B.
core  

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