Results 31 to 40 of about 9,922 (249)

Plant seed-inspired cell protection, dormancy, and growth for large-scale biofabrication

open access: yes, 2019
Biofabrication technologies have endowed us with the capability to fabricate complex biological constructs. However, cytotoxic biofabrication conditions have been a major challenge for their clinical application, leading to a trade-off between cell ...
Song, Juha   +6 more
core   +1 more source

Cell encapsulation in gelatin methacryloyl bioinks impairs microscale diffusion properties

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Light-assisted bioprinted gelatin methacryloyl (GelMA) constructs have been used for cell-laden microtissues and organoids. GelMA can be loaded by desired cells, which can regulate the biophysical properties of bioprinted constructs.
Elvan Dogan   +5 more
doaj   +1 more source

Zwitterionic polymer-dexamethasone conjugates penetrate and protect cartilage from inflammation

open access: yesMaterials Today Bio
Improving the pharmacokinetics of intra-articularly injected therapeutics is a major challenge in treating joint disease. Small molecules and biologics are often cleared from the joint within hours, which greatly reduces their therapeutic efficacy ...
Patrick Weber   +3 more
doaj   +1 more source

A heuristic computational model of basic cellular processes and oxygenation during spheroid-dependent biofabrication

open access: yes, 2017
An emerging approach in biofabrication is the creation of 3D tissue constructs through scaffold-free, cell spheroid-only methods. The basic mechanism in this technology is spheroid fusion, which is driven by the minimization of energy, the same ...
Sego, T. J.   +9 more
core   +1 more source

4D Biomimetic Wrinkled Porous Textiles via Electrospinning and Melt Electrowriting for Advanced Strain Sensing

open access: yesSmall Structures
We present an innovative strategy for fabricating strain sensors based on nonwoven, porous, and wrinkled textile architectures that mimic the mechanical behavior of biological tissues.
Zhander Vohr Soreño   +3 more
doaj   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

open access: yesAdvanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez   +8 more
wiley   +1 more source

Topologically close-packed structure characteristics of the plastic deformation regions of amorphous Cu64.5Zr35.5

open access: yesJournal of Materials Research and Technology, 2022
Understanding the structure of the plastic deformation region is important for improving the mechanical property of amorphous alloys. What kind of structure is conducive to the formation of deformation zone is however still unclear yet.
Li-li Zhou   +7 more
doaj   +1 more source

Spatially Controlled Embedded Bioprinting of Prevascularized Spheroids‐Containing Biopatch Enables Functional Skin Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn   +6 more
wiley   +1 more source

Recent advances in biofabrication strategies based on bioprinting for vascularized tissue repair and regeneration

open access: yesMaterials & Design, 2023
Vascularization plays a crucial role in transporting and exchanging nutrients and oxygen between implanted grafts with the host tissue. In the biofabrication of the implanted grafts, remodeling the vascular networks can accelerate vascularized tissue ...
Fei Xing   +9 more
doaj   +1 more source

Biofabrication: The future of regenerative medicine

open access: yes, 2016
The hospital of the future will incorporate revolutionary technologies that will transform health care, delivering highly automated, personalized, and customized patient solutions.
Powell, Sean K.   +5 more
core   +1 more source

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