Results 41 to 50 of about 9,922 (249)

Magnetically Driven Biofabrication for Tissue Engineering: From Nanoparticle Design to Mag‐ATMP Translation

Advanced Healthcare Materials, EarlyView.
Magnetically responsive nanoparticles enable remote control over biomaterials, cells, and engineered tissues. This review summarizes material design, biological safety, fabrication and actuation strategies, computational validation, and translational pathways that support the development of magnetic tissue‐engineering platforms and future magnetically ...
Konstantinos Ioannidis, Dimitrios Lefas, Maya Guilliams, Jackie Van Grootenbril, Isaak Decoene, Dimitrios Sakellariou, Bart Smeets, Stefanos Mourdikoudis, Ioannis Papantoniou   +8 more
wiley   +1 more source

Biofabrication of nanovesicles for brain diseases

Neural Regeneration Research, 2022
Nanotechnologies promise to improve disease diagnosis and treatment, overcoming the limitations of conventional administrations. In particular, extracellular vesicles (EVs) and artificial vesicles (AVs) are strongly emerging tools in nanomedicine (Leggio et al., 2020). EVs are cell-derived membrane structures secreted after the fusion of endosomes with
Pasquale Picone, Domenico Nuzzo
openaire   +4 more sources

Computational methods for biofabrication in tissue engineering and regenerative medicine - a literature review

Computational and Structural Biotechnology Journal
This literature review rigorously examines the growing scientific interest in computational methods for Tissue Engineering and Regenerative Medicine biofabrication, a leading-edge area in biomedical innovation, emphasizing the need for accurate, multi ...
Roberta Bardini, Stefano Di Carlo
doaj   +1 more source

Nanotechnological Strategies for Biofabrication of Human Organs

Journal of Nanotechnology, 2012
Nanotechnology is a rapidly emerging technology dealing with so-called nanomaterials which at least in one dimension have size smaller than 100 nm. One of the most potentially promising applications of nanotechnology is in the area of tissue engineering,
Rodrigo A. Rezende, Fábio de Souza Azevedo, Frederico David Pereira, Vladimir Kasyanov, Xuejun Wen, Jorge Vicente Lopes de Silva, Vladimir Mironov   +6 more
doaj   +1 more source

Turing Instability-Driven Biofabrication of Branching Tissue Structures: A Dynamic Simulation and Analysis Based on the Reaction–Diffusion Mechanism †

Micromachines, 2018
Four-dimensional (4D) biofabrication techniques aim to dynamically produce and control three-dimensional (3D) biological structures that would transform their shapes or functionalities with time, when a stimulus is imposed or cell post-printing self ...
Xiaolu Zhu, Hao Yang
doaj   +1 more source

Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi, Matthew B. Baker, Dominik Schauenburg   +2 more
wiley   +1 more source

Guiding cell migration in 3D with high-resolution photografting

Scientific Reports, 2022
Multi-photon lithography (MPL) has proven to be a suitable tool to precisely control the microenvironment of cells in terms of the biochemical and biophysical properties of the hydrogel matrix.
Simon Sayer, Tommaso Zandrini, Marica Markovic, Jasper Van Hoorick, Sandra Van Vlierberghe, Stefan Baudis, Wolfgang Holnthoner, Aleksandr Ovsianikov   +7 more
doaj   +1 more source

Provision of Human Brain Microenvironment with Brain-Specific Extracellular Matrix

, 2022
1
CHO, DONG WOO, JANG, JIN AH, Cho, Hansang, Ngo, Huyen, BAE, MIHYEON   +4 more
core  

A Hybrid Bioprinting–Microfabrication Approach to Controllable Multitype Spheroid Arrays for Modeling Tumor Heterogeneity

Advanced Healthcare Materials, EarlyView.
This work introduces a “cancer‐in‐a‐well” technology that recreates tumor heterogeneity in vitro using multitype spheroid arrays. Combining bioprinting/microdispensing with microstructured culture devices, the system improves drug screening and modeling of tumor complexity.
Simone Bonetti, Eva Clemente, Emanuela Mensà, Marco de Maria, Fulvia Farabegoli, Emanuela Saracino, Barbara Bortolani, Emanuela Marcelli, Renato Brandimarti, Dario de Biase, Giampaolo Zuccheri   +10 more
wiley   +1 more source

Zwitterionic poly-carboxybetaine-dexamethasone conjugates do not alleviate cartilage degeneration and synovitis in the collagenase-induced osteoarthritis model in rats

Scientific Reports
Osteoarthritis is a degenerative joint disease for which there is yet to be a disease-modifying drug available in clinics. New drug candidates often fail due to a combination of poor pharmacokinetics as well as an inability to address the complex ...
Patrick Weber, Maryam Asadikorayem, Shipin Zhang, David Fercher, Kajetana Bevc, Sami Kauppinen, Tuomas Frondelius, Tianqi Zhang, Marina Fonti, Gonçalo Barreto, Mikko A.J. Finnilä, Marcy Zenobi-Wong   +11 more
doaj   +1 more source