Results 51 to 60 of about 9,922 (249)

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

open access: yesAdvanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab   +8 more
wiley   +1 more source

Filamented hydrogels as tunable conduits for guiding neurite outgrowth

open access: yesMaterials Today Bio
Anisotropic scaffolds with unidirectionally aligned fibers present an optimal solution for nerve tissue engineering and graft repair. This study investigates the application of filamented light (FLight) biofabrication to create hydrogel matrices ...
Hao Liu   +4 more
doaj   +1 more source

Spatial Control of Light‐Responsive Proteins and Optogenetics Within Hydrogels via Volumetric Bioprinting

open access: yesAdvanced Materials, EarlyView.
Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi   +14 more
wiley   +1 more source

Modular iodinated carboxybetaine copolymers as charge-sensitive contrast agents for the detection of cartilage degradation

open access: yesMaterials Today Bio
Accurately assessing cartilage tissue degradation is a big challenge in osteoarthritis (OA) research, as histology only provides information about a 2D tissue section, and currently available contrast agents for tomographic evaluation suffer from low ...
Patrick Weber   +4 more
doaj   +1 more source

Biofabrication of natural hydrogels for cardiac, neural, and bone Tissue engineering Applications

open access: yesBioactive Materials, 2021
Natural hydrogels are one of the most promising biomaterials for tissue engineering applications, due to their biocompatibility, biodegradability, and extracellular matrix mimicking ability.
Kamil Elkhoury   +5 more
doaj   +1 more source

S‐Nitrosothiols as Thiol‐Protecting Groups for Controlled Thiol‐Maleimide Crosslinking of Homogeneous Soft Hydrogels

open access: yesAdvanced Materials, EarlyView.
Rapid thiol‐maleimide addition frequently outpaces mixing, resulting in heterogeneous hydrogels. S‐nitrosothiols act as thiol‐protecting groups, allowing uniform mixing with maleimide‐functionalized polymers before gelation. Sodium thiosulfate or sodium ascorbate then regenerates thiols on demand, triggering controlled thiol‐maleimide crosslinking ...
Julian A. Serna   +7 more
wiley   +1 more source

Biofabrication of Human Skin with Its Appendages

open access: yesAdvanced Healthcare Materials, 2022
AbstractMuch effort has been made to generate human skin organ in the laboratory. Yet, the current models are limited due to the lack of many critical biological and structural features of the skin. Importantly, these in vitro models lack appendages and fail to recapitulate the whole human skin construction.
Motaharesadat Hosseini   +2 more
openaire   +5 more sources

All‐Amyloid Functional Coacervates

open access: yesAdvanced Materials, EarlyView.
This study introduces an all‐amyloid interfacial complex coacervate technique that employs charge‐mediated or functionalization‐assisted complexation of oppositely charged food protein‐derived amyloid nanofibrils to engineer functional soft constructs across multiple length scales.
Seyyed Alireza Hashemi   +4 more
wiley   +1 more source

Beyond the matrix: rethinking antibiotic tolerance in CF biofilms using 3D models

open access: yesnpj Biofilms and Microbiomes
Chronic lung infections in cystic fibrosis (CF) patients are associated with Pseudomonas aeruginosa biofilms exhibiting high antibiotic tolerance with no clear explanation.
Goodness Ogechi Osondu-Chuka   +5 more
doaj   +1 more source

Upscaling the Fabrication of Rod‐Shaped Microgels: A Microfluidic Method Combining Step‐Emulsification With Consecutive Droplet Confinement in Parallelized Microchannels

open access: yesAdvanced Materials, EarlyView.
A microfluidic method is presented which enables parallelized fabrication of rod‐shaped microgels, based on step‐emulsification (SE) droplet generation and subsequent droplet distribution and confinement, combined in a single device. Microgel rods are fabricated in parallel at different flow rates based on two light‐mediated crosslinking chemistries ...
Matthias Mork   +5 more
wiley   +1 more source

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