Results 11 to 20 of about 1,724 (167)
Treatment with a Zinc Metalloprotease Purified from Bothrops moojeni Snake Venom (BmooMP-Alpha-I) Reduces the Inflammation in an Experimental Model of Dextran Sulfate Sodium-Induced Colitis. [PDF]
Mediators Inflamm, 2019 It has been described that the metalloprotease BmooMP‐alpha‐I purified from Bothrops moojeni snake venom is able to hydrolyze the TNF molecule. However, this observation has been based mainly on in vitro investigation, in addition to molecular modeling and docking approaches.
Silva MC +7 more
europepmc +2 more sources
Requisitos de bioisenção com base no Sistema de Classificação Biofarmacêutica no Brasil e no mundo
Revista de Direito Sanitário, 2021 O acesso a medicamentos pode ser facilitado por programas globais de desenvolvimento farmacêutico, mas há necessidade de que as agencias regulatórias e as indústrias farmoquímicas e farmacêuticas interajam e haja um consenso quanto as exigências para o ...
Valéria Sant'Anna Dantas Esteves +2 more
semanticscholar +1 more source
Molecular Oncology, Volume 16, Issue 4, Page 904-920, February 2022., 2022 Our study investigates the molecular effects elicited by the vitamin D derivative calcitriol in patients with breast cancer (BC). We showed that ERRα deregulated calcitriol/VDR‐dependent transcription, causing estrogen pathway activation and upregulation of the calcitriol degradation enzyme CYP24A1.
Katia Danza +8 more
wiley +1 more source
Ars Pharmaceutica, 2021 Introducción: el Diazepam pertenece a un grupo de medicamentos llamados benzodiazepinas. Se sabe que estos medicamentos actúan en el cerebro a través del GABA.
Segundo Francisco Saavedra Suárez +4 more
semanticscholar +1 more source
A New Platelet-Aggregation-Inhibiting Factor Isolated from Bothrops moojeni Snake Venom. [PDF]
Biomed Res Int, 2017 This work reports the purification and functional characterization of BmooPAi, a platelet‐aggregation‐inhibiting factor from Bothrops moojeni snake venom. The toxin was purified by a combination of three chromatographic steps (ion‐exchange on DEAE‐Sephacel, molecular exclusion on Sephadex G‐75, and affinity chromatography on HiTrap™ Heparin HP ...
de Sousa BB +9 more
europepmc +2 more sources
Revista Contexto & Saúde, 2021 RESUMO Os excipientes são componentes fundamentais de uma preparação farmacêutica, estabilizando o princípio ativo, favorecendo sua solubilidade durante o processo de preparação e sua absorção após administração.
Adriana Carrer Stefanini Gemeinder +2 more
doaj +1 more source
Revista Cubana de Administración Pública y Empresarial, 2023 El tercer número del séptimo volumen de 2023 de la Revista Cubana de Administración Pública y Empresarial aborda buenas prácticas de gestión. Conforman el número artículos originales, con autores de Cuba, Ecuador y Brasil.
Mercedes Delgado Fernández
doaj +1 more source
Frontiers in Pharmacology, 2014 Recent clinical research has shown that atorvastatin in combination with cholesterol absorption inhibitor ezetimibe significantly reduces LDL-C level in patients with hypercholesterolemia, showing a superior lipid-lowering efficacy compared to statin ...
Omar ePatiño-Rodríguez +4 more
doaj +1 more source
Memorias del Instituto de Investigaciones en Ciencias de la Salud, 2020 El Alprazolam pertenece a las benzodiazepinas. Sus efectos se atribuyen a que actúa sobre receptores de membrana específicos, lo cual facilita la acción inhibitoria presináptica y postsináptica del ácido γ-aminobutírico (GABA), especialmente en la ...
Lennin Roswell Rodriguez-Saavedra +4 more
semanticscholar +1 more source
Revista Peruana de Medicina Experimental y Salud Pública, 2019 El objetivo del estudio fue determinar la equivalencia terapéutica evaluada mediante estudios in vitro de cuatro marcas de medicamentos conteniendo amoxicilina, doxiciclina y fluconazol adquiridos en establecimientos farmacéuticos de Lima Metropolitana y
Miguel Grande-Ortiz +4 more
doaj +1 more source