Results 211 to 220 of about 449,966 (339)

Unraveling the role of mitochondrial dysfunction in diabetic kidney disease: insights and interventions. [PDF]

Front Pharmacol
Fan Z, Luo P, Gao Y, Ma H, Fan J, Sanan S, Zhang P, Lu K, Xia H.   +8 more
europepmc   +1 more source

Chloroplast Stress Signals Orchestrate Epidermis‐Specific Remodeling of Mitochondria and ER Under High Light

Advanced Science, EarlyView.
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos, Hee‐Seung Choi, Jingzhe Guo, Andrea A. Zanini, Tessa M. Burch‐Smith, Emily Snyder, Matthew Part, Wilhelmina van de Ven, Manhoi Hur, Gerd Ulrich Balcke, Alain Tissier, Quanqing Zhang, Katayoon Dehesh   +12 more
wiley   +1 more source

Faculty Opinions recommendation of PIKfyve regulates melanosome biogenesis.

, 2020
Mitsunori Fukuda, Norihiko Ohbayashi
openalex   +2 more sources

Parallel Genome‐Wide CRISPR Screens Reveal SORL1 and ZFYVE19 as Sequential Host Determinants of Salmonella Infection

Advanced Science, EarlyView.
To distinguish how Salmonella invades cells vs how it survives long‐term, a parallel CRISPR screening platform is developed. This approach reveals the host proteins that the bacterium exploits at different stages of infection. The study identifies SORL1 as a novel host factor for invasion and demonstrates that blocking it with an antibody effectively ...
Sehee Yun, Seoyeon Kim, Seonggyu Kim, Minsoo Noh, Dae‐Kyum Kim, Eun‐Jin Lee, Hunsang Lee   +6 more
wiley   +1 more source

Disrupted miRNA Biogenesis Machinery Reveals Common Molecular Pathways and Diagnostic Potential in MDS and AML. [PDF]

Biomedicines
Çevik K, Ay ME, Tombak A, Ay Öİ, Karakaş Ü, Erdal ME.   +5 more
europepmc   +1 more source

TOR and heat shock response pathways regulate peroxisome biogenesis during proteotoxic stress [PDF]

Nandini Shukla, Maxwell L. Neal, Jean‐Claude Farré, Fred D. Mast, Linh Truong, Theresa Simon, Leslie R. Miller, John D. Aitchison, Suresh Subramani   +8 more
openalex   +1 more source

Molecular Basis of Exercise-Induced Skeletal Muscle Mitochondrial Biogenesis: Historical Advances, Current Knowledge, and Future Challenges [PDF]

, 2017
Christopher G. R. Perry, John A. Hawley
openalex   +1 more source

Biogenesis

The American Biology Teacher, 2006
openaire   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

Mitochondrial quality control mechanisms as molecular targets for impaired lung development: from fetuses to neonates. [PDF]

Respir Res
Zhu Z, Zhang L, Fu J.
europepmc   +1 more source