Results 271 to 280 of about 439,213 (293)

Biochemical and spectroscopic analysis of two key proteins involved in FeS-clusters biogenesis [PDF]

, 2018
Lorenzo Maso
openalex  

The Immune Microenvironment in Liver Cancer: From Analysis to Targeting

Advanced Science, EarlyView.
This review explores how smart nanomedicines overcome the immunosuppressive tumor microenvironment in liver cancer. It details targeted delivery strategies and immune reprogramming mechanisms, including remodeling abnormal physiology, modulating metabolism, and inducing immunogenic cell death. The article highlights the paradigm shift toward multimodal
Jiaming Lan, Hao Li, Jian Xue, Yourong Duan, Jin Sun, Meng Niu   +5 more
wiley   +1 more source

Decoding the Lipid Droplet Proteome: New Frontiers in Cardiovascular Disease Research. [PDF]

Int J Mol Sci
Mallia A, Papaianni GG, Brocca L, Banfi C, Gianazza E.   +4 more
europepmc   +1 more source

A Supramolecular Nanoscavengers: Based “Cargo‐Exchange” Breaking Cholesterol Metabolic Dysregulation for Glioblastoma Therapy

Advanced Science, EarlyView.
Dysregulated cholesterol metabolism, driven by a complex array of mechanisms, is a defining characteristic of glioblastoma (GBM). In this study, supramolecular nanoscavengers are engineered by harnessing the intrinsic binding affinity between endogenous small‐molecule cholesterol and β‐cyclodextrin (β‐CD).
Zonghua Tian, Yun Chen, Jingyi Zhou, Shilin Zhang, Hongrui Fan, Xuwen Li, Tao Sun, Chen Jiang   +7 more
wiley   +1 more source

HUWE1 loss promotes stemness and drug resistance in CRC with dysregulated β-catenin destruction complex. [PDF]

Cell Death Discov
Lee C, Park SH, Han IO, Kim Yoon S.
europepmc   +1 more source

Research Progress on Idebenone in Neurodegenerative Diseases

AGING MEDICINE, EarlyView.
The study not only summarizes the biological properties of Idebenone (IDE), including its role in improving mitochondrial function and antioxidative stress, but also explores its clinical research progress in various neurodegenerative diseases, providing a new perspective for the treatment of these disorders.
Yanqing Zhang, Yanhong Ren, Xiaoran Zhu, Tianhao Liu, Rundong Han, Yuqing Fang, Zhangning Zhao, Fei Mao, Yalin Wang, Xian Li, Xiuhua Li   +10 more
wiley   +1 more source

Lipid metabolism and lipid signaling in extracellular vesicles ontogeny: from biogenesis to functional execution. [PDF]

J Nanobiotechnology
Zhang J, Li J, Zheng Y, Zhu C, Wu Z, Wang T, Li Y, Zhu J, Wei S, Qian H, Sun Z.   +10 more
europepmc   +1 more source

A Versatile AIEgen for In Situ Monitoring of Entire ApoVs Formation Processes

Aggregate, EarlyView.
This work developed a versatile AIEgen for in situ monitoring of the entire ApoVs formation processes, and demonstrated that ApoVs originate from plasma‐membrane protrusions. ABSTRACT Apoptotic vesicles (ApoVs) are membrane structures formed during cell apoptosis and play crucial roles in homeostasis maintenance, signal transduction, and immune ...
Qiuhua Hao, Nan Sheng, Jie Niu, Chi Li, Fangfang Meng, Xingyu Lyu, Jiaxuan Wang, Zhiqiang Liu, Xiaoqiang Yu   +8 more
wiley   +1 more source

PLINs-mediated organelle interactions: a key of exercise-mediated improvement of skeletal muscle lipid metabolism disorders. [PDF]

Front Endocrinol (Lausanne)
Liu Z, Zhao Y.
europepmc   +1 more source

circNR3C2 promotes chondrogenic differentiation and cartilage repair of human adipose‐derived stem cells via the hsa‐miR‐647/SOX9 pathway

Animal Models and Experimental Medicine, EarlyView.
The hypothesis diagram illustrates the function and mechanism of circNR3C2: circNR3C2 overexpression can up‐regulate COL2, Aggrecan and SOX9 expression, and regulate chondrogenic differentiation of hADSCs by targeting hsa‐miR‐647. Abstract Background Human adipose‐derived stem cells (hADSCs) are seed cells with application prospects in cartilage repair.
Dabiao Hou, Huajun Wang, Hao Guo, Dongbin Luo, Xiaofei Zheng, Simin Luo   +5 more
wiley   +1 more source