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Mitoribosome Biogenesis

2023
Mitoribosome biogenesis is a complex and energetically costly process that involves RNA elements encoded in the mitochondrial genome and mitoribosomal proteins most frequently encoded in the nuclear genome. The process is catalyzed by extra-ribosomal proteins, nucleus-encoded assembly factors that act in all stages of the assembly process to coordinate
J, Conor Moran   +4 more
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Peroxisome biogenesis

BioEssays, 1997
AbstractPeroxisomes are eukaryotic organelles that are the subcellular location of important metabolic reactions. In humans, defects in the organelle's function are often lethal. Yet, relative to other organelles, little is known about how cells maintain and propagate peroxisomes or how they direct specific sets of newly synthesized proteins to these ...
H R, Waterham, J M, Cregg
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Peroxisome Biogenesis

Annual Review of Cell and Developmental Biology, 2001
▪ Abstract  Fifteen years ago, we had a model of peroxisome biogenesis that involved growth and division of preexisting peroxisomes. Today, thanks to genetically tractable model organisms and Chinese hamster ovary cells, 23 PEX genes have been cloned that encode the machinery (“peroxins”) required to assemble the organelle.
P E, Purdue, P B, Lazarow
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