Results 31 to 40 of about 3,840 (112)

Bioinformática en Colombia: presente y futuro de la investigación biocomputacional

Biomédica: revista del Instituto Nacional de Salud, 2010
La bioinformática, como la conocemos hoy en día, es una de las ciencias con mayor proyección en la adquisición de conocimiento científico. Contrario a lo que se piensa, esta ciencia tuvo sus inicios en los años 50, pero no fue sino hasta hace un par de ...
Alfonso Benítez-Páez, Sonia Cárdenas-Brito   +1 more
doaj   +1 more source

Gender Medicine in Computed Tomography Radiomics Analysis to Predict Disease Progression in Liver Respectable Colorectal Cancer Patients

Cancer Medicine, Volume 14, Issue 17, September 2025.
ABSTRACT Background Gender medicine is an evolving discipline that examines how diseases manifest and progress differently in men and women. Tailoring medical therapies and diagnostic approaches can enhance patient outcomes. While radiomics is emerging as a promising tool in personalized medicine, few studies evaluate its role in gender medicine within
Annarita Fanizzi, Arianna Campione, Samantha Bove, Oronzo Brunetti, Deniz Can Guven, Angelo Cirillo, Andrea Lupo, Chiara Macrì, Leonardo Ricchitelli, Alessandro Rizzo, Elsa Vitale, Maria Colomba Comes, Raffaella Massafra   +12 more
wiley   +1 more source

La aplicación de las ciencias bioforenses a la investigación del bioterrorismo y biocrimen

Ciencia Policial
En los últimos años las técnicas de biología molecular han experimentado un avance enorme en todos sus campos. Esto hace que las capacidades de análisis cualitativo, cuantitativo y de tiempos de procesamiento hayan mejorado mucho, en especial con la ...
Desiderio José Ordoño Ballesteros
doaj   +1 more source

South‐to‐Southeast Expansion of HIV‐1 Subtype C in Brazil

Journal of Medical Virology, Volume 97, Issue 9, September 2025.
ABSTRACT HIV‐1 group M subtype C (HIV‐1C) is the predominant genetic variant in southern Brazil but has been sparsely detected in other regions of the country. Our study aimed to identify HIV‐1C transmission links across Brazil using phylogenetic reconstruction and to infer trends in geographical patterns and dissemination beyond the southern region ...
Daniel Polita, Laise de Moraes, Marta Giovanetti, Filipe Ferreira de Almeida Rego, Gabriel Carvalho, Luciane Amorim Santos, Ricardo Khouri, Dennis Maletich Junqueira   +7 more
wiley   +1 more source

Recursos de bioinformática aplicados às ciências ômicas como genômica, transcriptômica, proteômica, interatômica e metabolômica

Bioscience Journal, 2010
As ciências ômicas tratam da análise global dos sistemas biológicos, integrando diferentes áreas do conhecimento, como a bioquímica, genética, fisiologia e computação, com o objetivo de isolar e caracterizar genes, proteínas e metabólitos, assim como ...
Foued Salmen Espindola, Luciana Karen Calábria, Alexandre Azenha Alves de Rezende, Boscolli Barbosa Pereira, Flávia Assumpção Santana, Isabel Marques Rodrigues Amaral, Janaina Lobato, Juliana Luzia França, Justino Luiz Mario, Leonardo Bruno Figueiredo, Luana Pereira dos Santos, Neire Moura de Gouveia, Rafael Nascimento, Renata Roland Teixeira, Taís Alves dos Reis, Thaise Gonçalves de Araújo   +15 more
doaj  

First Assembly of a Draft Genome of the Critically Endangered Northern Muriqui (Brachyteles hypoxanthus, Primates, Atelidae) Including Non‐Invasive Genotyping Strategies for the Species

Ecology and Evolution, Volume 15, Issue 8, August 2025.
First draft genome assembly of the critically endangered primate northern muriqui (Brachyteles hypoxanthus) and complete mitochondrial genome assembly. Set of microsatellite markers developed for the species for genotyping‐by‐sequencing using high‐throughput sequencing technology and aiming to amplify non‐invasive sampling for population genetics ...
Amanda Alves de Melo‐Ximenes, Romina Batista, Leonardo Carlos Jeronimo Corvalán, Tomas Marques‐Bonet, Lukas Kuderna, Kyle Farh, Jeffrey Rogers, Mariane da Cruz Kaizer, Jean Philippe Boubli, Fabiano Rodrigues de Melo, Rhewter Nunes, Mariana Pires de Campos Telles   +11 more
wiley   +1 more source

Genetic Variants Affect Distinct Metabolic Pathways in Pediatric Multisystem Inflammatory Syndrome and Severe COVID‐19

Journal of Medical Virology, Volume 97, Issue 8, August 2025.
ABSTRACT The coronavirus disease 2019 (COVID‐19) pandemic has triggered a global health crisis, with over 700 million confirmed cases and at least 7 million deaths reported by early 2024. Children are less vulnerable to severe SARS‐CoV‐2 infection than adults and typically experience milder respiratory symptoms.
Alysson Henrique Urbanski, Flávia Cristina de Paula Freitas, Tiago Minuzzi Freire da Fontoura Gomes, Michelle Orane Schemberger, Bárbara Carvalho Santos dos Reis, Flavia Amêndola Anísio de Carvalho, Roberta Soares Faccion, Lucas de Almeida Machado, Deborah Antunes dos Santos, Daniela Prado Cunha, Margarida dos Santos Salú, Daniella Campelo Batalha Cox Moore, Mayra Marinho Presibella, Juliana Fontes Noguchi, Henrique Lira Borges, Lais Kimie Tomiura, Luiza Silva de Castro, Letícia Graziela Costa Santos, Esdras Matheus Gomes da Silva, Vinícius Da Silva Coutinho Parreira, Luis Gustavo Morello, Fabricio Klerynton Marchini, Maria Regina Tizzot, Mauricio Marcondes Ribas, Gilberto Pascolat, Carmen Australia Paredes Marcondes Ribas, Fábio Fernandes da Rocha Vicente, Alexandre Rossi Paschoal, Rubens Cat, Benilton de Sá Carvalho, Jaqueline Carvalho de Oliveira, Marcus F. Oliveira, Luiz Lehmann Coutinho, Acácia Maria Lourenço Francisco Nasr, Irina Nastassja Riediger, Jeanine Marie Nardin, Liya Regina Mikami, Ana Carolina Ramos Guimarães, Patricia Savio de Araujo‐Souza, Arnaldo Prata‐Barbosa, Zilton Farias Meira de Vasconcelos, Helisson Faoro, Hellen Geremias dos Santos, Fabio Passetti   +43 more
wiley   +1 more source

Aplicaciones de la bioinformática en la medicina: el genoma humano. ¿Cómo podemos ver tanto detalle?

Acta Biológica Colombiana, 2016
La bioinformática es un campo novedoso que soporta parte de la investigación biológica dirigida a la identificación de variantes génicas que pueden ser descubiertas desde los estudios de genomas completos.
Clara Isabel Bermudez-Santana
doaj   +1 more source

Oropouche Virus Importation in Southern Brazil and Emerging Concern Calling for Enhanced Public Health Surveillance

Journal of Medical Virology, Volume 97, Issue 8, August 2025.
ABSTRACT Oropouche virus (OROV), an arthropod‐borne virus transmitted by Culicoides paraensis, is an endemic arbovirus that historically circulates mostly in the Amazon basin. Between 2022 and 2024, it reemerged as a more widespread public health concern in South America.
Franciellen Machado dos Santos, Elverson Soares de Melo, Gustavo Barbosa de Lima, Alexandre Freitas da Silva, Marcelo Henrique Santos Paiva, Bartolomeu Acioli‐Santos, Clarice Neuenschwander Lins de Moraes, Amanda Pellenz Ruivo, Tatiana Schäffer Gregianini, Milena Bauermann, Thales Bermann, Valeska Lizzi Lagranha, Ludmila Fiorenzano Baethgen, Fernanda Godinho, Gabriel da Luz Wallau, Ana Beatriz Gorini da Veiga, Richard Steiner Salvato   +16 more
wiley   +1 more source

Identificación de inhibidores de PI3Kα mediante diseño de farmacóforos y reposicionamiento farmacológico†

Horizonte Médico
Objetivo: PI3K es una de las proteínas más comunes que sufren mutaciones en el cáncer, ello genera que se altere su función en la regulación del metabolismo, la inmunidad, entre otros.
Paolo Wong Chero, Daniel Ramirez Lupuche, Richard Zapata Dongo, Stefany Infante Varillas, Juan Enrique Faya Castillo   +4 more
doaj   +1 more source