Results 31 to 40 of about 257,337 (308)

The haloarchaeal MCM proteins: bioinformatic analysis and targeted mutagenesis of the β7-β8 and β9-β10 hairpin loops and conserved zinc binding domain cysteines [PDF]

, 2014
The hexameric MCM complex is the catalytic core of the replicative helicase in eukaryotic and archaeal cells. Here we describe the first in vivo analysis of archaeal MCM protein structure and function relationships using the genetically tractable ...
Tatjana P Kristensen, Reeja Maria Cherian, Reeja eMaria Cherian, Stuart A MacNeill, MacNeill, Stuart, Kristensen, Tatjana P., Fiona C Gray, Gray, Fiona C., Fiona C. Gray, Tatjana P. Kristensen, Stuart A. MacNeill, Cherian, Reeja Maria, Macneill, Stuart Andrew   +12 more
core   +1 more source

The schematic representation of bioinformatic analysis.

, 2023
The schematic representation of bioinformatic analysis.
Ning Zhang (23771), Wu Liu (680761), Yi Zhou (2723), Yutian Hu (14833713), Tong Liu (107783), Kaifeng Shi (14833716), Jiaqi Huang (79038)   +6 more
core   +1 more source

Aptamer Bioinformatics [PDF]

International Journal of Molecular Sciences, 2017
Aptamers are short nucleic acid sequences capable of specific, high-affinity molecular binding. They are isolated via SELEX (Systematic Evolution of Ligands by Exponential Enrichment), an evolutionary process that involves iterative rounds of selection and amplification before sequencing and aptamer characterization.
Andrew Kinghorn, Lewis Fraser, Shaolin Liang, Simon Shiu, Julian Tanner   +4 more
openaire   +2 more sources

Diagram-of-bioinformatic-pipelines

, 2012
Diagram-of-bioinformatic ...
Bodles, William, Buggs, Richard, Alan Watson Featherstone (3285507), Marian Thomson (3285516), Robert Crawford (3285531), Richard Buggs (3285528), Harriet Hunt (226067), William Bodles (3285525), Nian Wang (215195), Crawford, Robert, Watson Featherstone, Alan, Thomson, Marian, Hunt, Harriet, Wang, Nian   +13 more
core   +1 more source

Bioinformatic commands used for generating consensus sequences.

, 2023
Bioinformatic commands used for generating consensus sequences.
Diego G. Diel (3154776), Leonardo Cardia Caserta (15852725), Jianqiang Zhang (613834), Pablo Piñeyro (426131)   +3 more
core   +1 more source

The Clinical Significance and Transcription Regulation of a DNA Damage Repair Gene, SMC4, in Low-Grade Glioma via Integrated Bioinformatic Analysis

Frontiers in Oncology, 2021
Glioma is the most common type of malignant tumor in the central nervous system with an unfavorable prognosis and limited treatment. In this study, we are devoted to addressing the prognostic value of DNA damage repair-related genes in low-grade glioma ...
Yan Wang, Zhisheng Wu
doaj   +1 more source

Microsatellite density landscapes illustrate short tandem repeats aggregation in the complete reference human genome

BMC Genomics
Background Microsatellites are increasingly realized to have biological significance in human genome and health in past decades, the assembled complete reference sequence of human genome T2T-CHM13 brought great help for a comprehensive study of short ...
Yun Xia, Douyue Li, Tingyi Chen, Saichao Pan, Hanrou Huang, Wenxiang Zhang, Yulin Liang, Yongzhuo Fu, Zhuli Peng, Hongxi Zhang, Liang Zhang, Shan Peng, Ruixue Shi, Xingxin He, Siqian Zhou, Weili Jiao, Xiangyan Zhao, Xiaolong Wu, Lan Zhou, Jingyu Zhou, Qingjian Ouyang, You Tian, Xiaoping Jiang, Yi Zhou, Shiying Tang, Junxiong Shen, Kazusato Ohshima, Zhongyang Tan   +27 more
doaj   +1 more source

Bioinformatic scripts

, 2015
Full scripts for bioinformatic pipeline as applied for sequence data analysis for Geisen et al.
Bonkowski, Michael, de Groot, G. Arjen, Antón Vizcaíno (3256647), Laros, Ivo, Vizcaíno, Antón, Stefan Geisen (3256650), G. Arjen de Groot (231852), Ivo Laros (3256644), Geisen, Stefan, Michael Bonkowski (458751)   +9 more
core   +1 more source

The GMOD Drupal Bioinformatic Server Framework [PDF]

, 2010
Motivation: Next-generation sequencing technologies have led to the widespread use of -omic applications. As a result, there is now a pronounced bioinformatic bottleneck.
Alexie Papanicolaou, David G. Heckel, Papanicolaou, A., Heckel, D., Papanicolaou, Alexie (R18102), Heckel, David G.   +5 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source