Results 151 to 160 of about 1,337,095 (390)
The PDTIS bioinformatics platform: from sequence to function - DOI: 10.3395/reciis.v1i2.Sup.98en
RECIIS, 2007 Since the eighties, Bioinformatics has acquired a growing importance in the biological sciences. Due to the complexity of hardware and software tools, and the need for a specialized management of network infrastructure, data processing and storage, many ...
Thomas Dan Otto +3 more
doaj
GitHub Statistics as a Measure of the Impact of Open-Source Bioinformatics Software
Frontiers in Bioengineering and Biotechnology, 2018 Modern research is increasingly data-driven and reliant on bioinformatics software. Publication is a common way of introducing new software, but not all bioinformatics tools get published.
Mikhail G. Dozmorov
doaj +1 more source
Germline variants in CDKN2A wild‐type melanoma prone families
Molecular Oncology, EarlyView.Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen +5 more
wiley +1 more source
Bioinformatics and Biomedical Informatics with ChatGPT: Year One Review [PDF]
arXivThe year 2023 marked a significant surge in the exploration of applying large language model (LLM) chatbots, notably ChatGPT, across various disciplines. We surveyed the applications of ChatGPT in bioinformatics and biomedical informatics throughout the year, covering omics, genetics, biomedical text mining, drug discovery, biomedical image ...
arxiv
A data-supported history of bioinformatics tools [PDF]
arXiv, 2018 Since the advent of next-generation sequencing in the early 2000s, the volume of bioinformatics software tools and databases has exploded and continues to grow rapidly. Documenting this evolution on a global and time-dependent scale is a challenging task, limited by the scarcity of comprehensive tool repositories.
arxiv
Bioinformatics tools for the study of microbial diversity [PDF]
, 1996 Hideaki Sugawara +3 more
openalex +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Diffusion models in bioinformatics and computational biology.
Nature Reviews Bioengineering, 2023 Zhiye Guo +6 more
semanticscholar +1 more source
Fighting against uncertainty: An essential issue in bioinformatics [PDF]
arXiv, 2013 Many bioinformatics problems, such as sequence alignment, gene prediction, phylogenetic tree estimation and RNA secondary structure prediction, are often affected by the "uncertainty" of a solution; that is, the probability of the solution is extremely small. This situation arises for estimation problems on high-dimensional discrete spaces in which the
arxiv
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source