Results 201 to 210 of about 592,104 (329)

Spatiotemporal Transcriptomic Profiling Reveals the Dynamic Immunological Landscape of Alveolar Echinococcosis

open access: yesAdvanced Science, EarlyView.
An unprecedented high‐resolution spatial atlas of the E. multilocularis infection foci is obtained, revealing the dynamic functions of neutrophils, Spp1+ macrophages, and fibroblasts during disease progression. The transition of parasite control strategy from “active killing” to “negative segregation” by the host may provide instructive insights into ...
Zhihua Ou   +35 more
wiley   +1 more source

UTAP2: an enhanced user-friendly transcriptome and epigenome analysis pipeline. [PDF]

open access: yesBMC Bioinformatics
Lindner J   +6 more
europepmc   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

open access: yesAdvanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao   +14 more
wiley   +1 more source

Lit-OTAR framework for extracting biological evidences from literature. [PDF]

open access: yesBioinformatics
Tirunagari S   +9 more
europepmc   +1 more source

Proceedings of the 16th Annual UT-KBRIN Bioinformatics Summit 2016: bioinformatics

open access: yesBMC Bioinformatics, 2017
Eric C. Rouchka   +46 more
doaj   +1 more source

Chromatin Organization Governs Transcriptional Response and Plasticity of Cancer Stem Cells

open access: yesAdvanced Science, EarlyView.
Through a combination of transcriptomic and histone mapping studies integrated with chromatin imaging, we define how chromatin organization in nanoscale packing domains fine tunes the plasticity of cancer stem cells (CSCs) driving evasion from and survival after chemotherapy.
Yinu Wang   +20 more
wiley   +1 more source

SpectroPipeR-a streamlining post Spectronaut® DIA-MS data analysis R package. [PDF]

open access: yesBioinformatics
Michalik S   +8 more
europepmc   +1 more source

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