Results 81 to 90 of about 1,268,351 (323)

Bioinformatics approach to enhance the undergraduate biology students’ understanding of plant terpenoid

open access: yesJPBI (Jurnal Pendidikan Biologi Indonesia)
Plant metabolite compounds have been applied on plant cellular metabolism, produces organic and inorganic compounds, primary and secondary bioactive molecules, such as glucose, amino acids, fat acids, alkaloids, flavonoids, and terpenoids. Undergraduate
Risanti Dhaniaputri   +2 more
doaj   +1 more source

The application of bioinformatics on academic thesis of Chinese graduate student: a bibliometric analysis base on VOSviewer [PDF]

open access: yesYixue xinzhi zazhi
Objective To analyze the application status of bioinformatics on Chinese medical graduate students.Methods Available academic thesis was filtered with a topic of bioinformatics medical research ranging from 2003 January 1st to 2023 December 31st in CNKI ...
LIU Junli   +4 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Causal Relationships Between Leukocyte Subsets and Adverse Fetal Outcomes: A Mendelian Randomization Study

open access: yesMediators of Inflammation
Conclusions: This study provided profound insights into the intricate regulatory mechanisms of leukocyte subsets in neonatal diseases, paving the way for new avenues in the diagnosis and treatment of associated disorders.
Hong Chen   +7 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Awareness and Predictors of the Use of Bioinformatics in Genome Research in Saudi Arabia

open access: yesInternational Journal of General Medicine, 2023
Lamya Alomair,1,2 Mostafa A Abolfotouh2,3 1AI and Bioinformatics Department, King Abdullah International Medical Research Center (KAIMRC), Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia; 2King Saud Bin-Abdulaziz University for Health ...
Alomair L, Abolfotouh MA
doaj  

Bioinformatics-Aided Venomics

open access: yesToxins, 2015
Venomics is a modern approach that combines transcriptomics and proteomics to explore the toxin content of venoms. This review will give an overview of computational approaches that have been created to classify and consolidate venomics data, as well as ...
Quentin Kaas, David J. Craik
doaj   +1 more source

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