Results 291 to 300 of about 1,093,449 (328)

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Identification and Bioinformatics Analysis of the HSP20 Family in the Peony. [PDF]

Genes (Basel)
Ma H, Yuan H, Bu W, Zhang M, Huang Y, Hu J, Cao J.   +6 more
europepmc   +1 more source

Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6

Advanced Science, EarlyView.
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu, Xinlin Xu, Yue Tong, Min Wang, Feng Ge, Min Wu, Yunlong Wang, Gang Chen, Xilan Yu, Shanshan Li   +9 more
wiley   +1 more source

Screening and validation of diagnostic markers for keloids via bioinformatics analysis. [PDF]

Biochem Biophys Rep
Wang Z, Hu B, Li W, Ma T, Li L.
europepmc   +1 more source

Integrative bioinformatics analysis identifies C1orf198 as a novel prognostic biomarker in colorectal cancer. [PDF]

PeerJ
Yang C, Geng X, Zhao Z.
europepmc   +1 more source

Disulfidptosis-associated gene signatures in sepsis: a diagnostic model based on an LLM-assisted bioinformatics analysis. [PDF]

Health Inf Sci Syst
Liu T, Mao Z, Chai J, Zhou H, Qu Y, Xu C, Chi Y.   +6 more
europepmc   +1 more source

Screening for biomarkers of tuberous sclerosis complex–associated epilepsy: a bioinformatics analysis

Yongsheng Sun, Haonan Ji, Liqin Xu, Raomeng Gu, Pasquale Striano, Gavin P. Winston, Bin Li, Hui Zhou   +7 more
openalex   +1 more source

Investigation for atherosclerotic plaque rupture with thrombosis in mice based on single-cell sequencing and bioinformatics analysis. [PDF]

Front Cardiovasc Med
Nie P, Wan F, Yao T, Li Y, Yan G, Pu J, Jin S.   +6 more
europepmc   +1 more source

Bioinformatics analysis and population sample validation of ferroptosis-related genes in coronary heart disease: A case-control study. [PDF]

Medicine (Baltimore)
Li LH, Chen CH, Dong QH, Xie YB.
europepmc   +1 more source

Bioinformatics and Sequence Analysis

, 2002
Panitz, Frank, Bendixen, Christian
openaire   +1 more source