Results 91 to 100 of about 8,295 (257)

Advanced Bioink for 3D Bioprinting of Complex Free-Standing Structures with High Stiffness

Bioengineering, 2020
One of the challenges in 3D-bioprinting is the realization of complex, volumetrically defined structures, that are also anatomically accurate and relevant. Towards this end, in this study we report the development and validation of a carboxylated agarose
Yawei Gu, Benjamin Schwarz, Aurelien Forget, Andrea Barbero, Ivan Martin, V. Prasad Shastri   +5 more
doaj   +1 more source

Development of Liver Decellularized Extracellular Matrix Bioink for Three-Dimensional Cell Printing-Based Liver Tissue Engineering

, 2019
The liver is an important organ and plays major roles in the human body. Because of the lack of liver donors after liver failure and drug-induced liver injury, much research has focused on developing liver alternatives and liver in vitro models for ...
BYOUNG, SOO KIM, KIM, HYEON JI, JANG, JINAH, DONG, HEON HA, HYUNGSEOK, LEE, CHO, DONG WOO, WONIL, HAN   +6 more
core   +1 more source

Bioprinted Tumor Microenvironment Models Reveal Immune Evasion and Guide CAR‐NK Therapeutic Strategies

Advanced Science, EarlyView.
This study presents a 3D embedded bioprinting platform that recapitulates key stromal features of the tumor microenvironment using fibroblasts and lung‐derived ECM. The model enables functional assessment of CAR‐NK cells and provides a versatile tool to support the development of next‐generation immunotherapeutic strategies against solid tumors ...
Dahong Kim, Seona Jo, In‐Hwan Jang, Yu‐Jin Kim, Youngmee Jung, Junhyoung Ahn, Hyungjun Lim, Jae Jong Lee, Kangwon Lee, Tae‐Don Kim, Su A Park   +10 more
wiley   +1 more source

Cell sheet based bioink for 3D bioprinting applications

, 2017
In this research, a novel development of bioink from cell sheets is presented for scaffold free bioprinting applications. Poly(N-isopropylacrylamide) (PNIPAAm) coated surfaces were first prepared by using initiated chemical vapor deposition method.
Toprakhisar, Burak, B Koc, Özaydın İnce, Gözde, Bakırcı, Ezgi, Koç, Bahattin, M C Zeybek, B Toprakhisar, E Bakirci, G O Ince, Zeybek, Mehmet Can   +9 more
core   +1 more source

Developmentally Inspired Bioprinting of Nascent Multicellular Human Heart Tissue Through in Situ Differentiation and Morphogenesis of iPSCs

Advanced Science, EarlyView.
A developmentally inspired bioprinting approach enables the fabrication of pluripotent tissues that undergo shape‐morphing and in situ cardiac lineage specification. This method employs embedded bioprinting to deposit iPSCs within soft granular hydrogels to create pluripotent tissue constructs that undergo cell‐mediated shape morphogenesis.
Ankita Pramanick, Juhi Chakraborty, Orlaith Kennedy, Hey Wei Wong, Sogol Kianersi, Daniel Kelly, Vasileios Sergis, Abhay Pandit, Andrew C. Daly   +8 more
wiley   +1 more source

Sviluppo e caratterizzazione di un bioink per l'ingegneria del tessuto retinico

, 2022
LAUREA MAGISTRALELe patologie che danneggiano l’occhio, causando ipovisione e cecità, colpiscono attualmente 285 milioni di persone nel mondo, di cui una gran parte sono patologie retiniche.
Caruso, Marta, Branca, Carlotta
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Microfluidic Bioprinting of Heterogeneous 3D Tissue Constructs Using Low-Viscosity Bioink

, 2016
A novel bioink and a dispensing technique for 3D tissue-engineering applications are presented. The technique incorporates a coaxial extrusion needle using a low-viscosity cell-laden bioink to produce highly defined 3D biostructures. The extrusion system
Dokmeci, Mehmet Remzi, Cristina Colosi, Andrea Barbetta, Solange Massa, Manoharan, Vijayan, Massa, Solange, Ali Khademhosseini, Barbetta, Andrea, Dentini, Mariella, Khademhosseini, Ali, Mehmet Remzi Dokmeci, Su Ryon Shin, Mariella Dentini, Vijayan Manoharan, Costantini, Marco, Shin, Su Ryon, Marco Costantini, Colosi, Cristina   +17 more
core   +1 more source

Biofabrication of skin tissue constructs using alginate, gelatin and diethylaminoethyl cellulose bioink.

, 2021
Introduction: Biofabrication of skin tissue equivalents using 3D bioprinting technology has gained much attention in recent times due to the simplicity, the versatility of the technology and its ability in bioengineering biomimetic tissue histology.
Bhatt, A, Renjith P., Nair, Lakshmi, TS, Suvanish, Kumar, Geevarghese, R, Riya, Raju, Kasoju, N   +6 more
core   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source