Results 81 to 90 of about 9,447 (273)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Extracellular Matrix/Amorphous Magnesium Phosphate Bioink for 3D Bioprinting of Craniomaxillofacial Bone Tissue [PDF]

, 2020
Bioprinting, a promising field in regenerative medicine, holds great potential to create three-dimensional, defect-specific vascularized bone with tremendous opportunities to address unmet craniomaxillofacial reconstructive challenges.
Malda, Jos, Bhaduri, Sarit B, Equine Musculoskeletal Biology, Bottino, Marco C, dES RMSC, Dubey, Nileshkumar, Ferreira, Jéssica   +6 more
core   +1 more source

Sustainable Fabrication of Tailored Bone Substitutes: From High‐Throughput Scaffold Manufacturing, Scaled‐Up HMSC Expansion to Dynamic Cultivation in a Perfusion Bioreactor

Advanced Science, EarlyView.
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun, Anna Paříková, Sandra Rother, Martin Kantor, Salman Muhammad Ilyas, Ricardo Bernhardt, Pavel Ndjawa Yomi, Jaromír Havlica, Revathi Appali, Benjamin Kruppke, Poh Soo Lee   +10 more
wiley   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Development of a Novel Bioink for Human Vascularized Organoids [PDF]

There is a need for a model to better mimic human physiology in the clinic, so the objective was to develop a novel bioink for a 3D tissue model to study human disease and development in a dynamic 3D environment. The results from each corresponding study
Bromet, Bradley Allen
core   +1 more source

Cell sheet based bioink for 3D bioprinting applications

, 2017
In this research, a novel development of bioink from cell sheets is presented for scaffold free bioprinting applications. Poly(N-isopropylacrylamide) (PNIPAAm) coated surfaces were first prepared by using initiated chemical vapor deposition method.
Toprakhisar, Burak, B Koc, Özaydın İnce, Gözde, Bakırcı, Ezgi, Koç, Bahattin, M C Zeybek, B Toprakhisar, E Bakirci, G O Ince, Zeybek, Mehmet Can   +9 more
core   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Sviluppo e caratterizzazione di un bioink per l'ingegneria del tessuto retinico

, 2022
LAUREA MAGISTRALELe patologie che danneggiano l’occhio, causando ipovisione e cecità, colpiscono attualmente 285 milioni di persone nel mondo, di cui una gran parte sono patologie retiniche.
Caruso, Marta, Branca, Carlotta
core  

From Flow to Function: Using Different Static Mixers to Fabricate Microarchitected Materials Via Chaotic Printing

Advanced Science, EarlyView.
Complex microarchitectures emerge from simple flow‐driven transformations as static mixers iteratively reorient and split material domains. Coupled with diverse deposition strategies, chaotic printing provides an accessible platform for fabricating architected materials that support biologically and chemically relevant processes. ABSTRACT Nature builds
Edna Johana Bolívar‐Monsalve, Carlos Fernando Ceballos‐González, Diego Alonso Quevedo‐Moreno, Irving Isaí Rendón‐Moreno, Ariel Cantoral‐Sánchez, Héctor Ambriz‐González, Mario Moisés Alvarez, Grissel Trujillo‐de Santiago   +7 more
wiley   +1 more source

Formulation and Characterization of Alginate Dialdehyde, Gelatin, and Platelet-Rich Plasma-Based Bioink for Bioprinting Applications

Bioengineering, 2020
Layer-by-layer additive manufacturing process has evolved into three-dimensional (3D) “bio-printing” as a means of constructing cell-laden functional tissue equivalents.
Lakshmi T. Somasekharan, Naresh Kasoju, Riya Raju, Anugya Bhatt   +3 more
doaj   +1 more source