Results 71 to 80 of about 11,817 (275)

Parallel 3D Bioprinting on SLIPS‐Microarrays

Advanced Functional Materials, EarlyView.
This work introduces the first truly parallel 3D bioprinting method, enabling both the simultaneous fabrication of hundreds of cell laden hydrogel 3D structures and their HTS in individual liquid compartments. By integrating Digital Light Processing (DLP) stereolithography with functional micropatterns, the platform decouples printing time from array ...
Julius von Padberg, Julian A. Serna, Maike Schliephake, Pavel A. Levkin   +3 more
wiley   +1 more source

A novel microplate 3D bioprinting platform for the engineering of muscle and tendon tissues [PDF]

, 2018
Two-dimensional (2D) cell cultures do not reflect the in vivo situation, and thus it is important to develop predictive three-dimensional (3D) in vitro models with enhanced reliability and robustness for drug screening applications.
Graf-Hausner, Ursula, Keller, Hansjoerg, Laternser, Sandra, Leupin, Olivier, Rausch, Martin, Rimann, Markus   +5 more
core   +1 more source

Tissue‐Stimulator Platform for Electrically Stimulating Pancreatic β‐Cells for Long‐Term Functional Regulation

Advanced Functional Materials, EarlyView.
We present a tissue‐stimulator platform for seamless electrode integration with pancreatic tissue, applying uniform electrical stimulation through optimized design with biohybrid 3D printing. Advantageous effects of electrical stimulation on β‐cell function were observed, including enhanced calcium signaling, islet morphology, and maturation.
Jihwan Kim, Uijung Yong, Myungji Kim, Jaewook Kim, Yeonggwon Jo, In Kyong Shim, Song Cheol Kim, Jinah Jang   +7 more
wiley   +1 more source

Assembly of Cell‐Seeded 3D Printed Hydrogel Modules with Perfusable Channel Networks

Advanced Functional Materials, EarlyView.
Macroscale assembly was utilized to prepare perfusable tissue constructs from individually 3D printed hydrogel modules with embedded branched channel networks and port arrays for cell seeding. Novel multi‐material bioreactors were fabricated to facilitate the gluing of individual modules and the perfusion culture of assembled modular constructs seeded ...
Zachary J. Geffert, Daniel Fougnier, Bo Van Durme, Jenna Grutzmacher, Ryan Clarke, Susan Cao, Zhenghao Li, Ujjwal Aryal, Jason A. Horton, Sandra Van Vlierberghe, Pranav Soman   +10 more
wiley   +1 more source

Progress in scaffold-free bioprinting for cardiovascular medicine [PDF]

, 2018
Biofabrication of tissue analogues is aspiring to become a disruptive technology capable to solve standing biomedical problems, from generation of improved tissue models for drug testing to alleviation of the shortage of organs for transplantation ...
Moldovan, Nicanor I.
core   +1 more source

Development of an extrusion-based 3D-printing strategy for clustering of human neural progenitor cells

Heliyon, 2022
3D bioprinting offers a simplified solution for the engineering of complex tissue parts for in-vitro drug discovery or, in-vivo implantation. However, significant amount of challenges exist in 3D bioprinting of neural tissues, as these are sensitive cell
Ines Bilkic, Diana Sotelo, Stephanie Anujarerat, Nickolas R. Ortiz, Matthew Alonzo, Raven El Khoury, Carla C. Loyola, Binata Joddar   +7 more
doaj   +1 more source

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

Advanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee, Mehdi Salar Amoli, Sarah Rezapourdamanab, Lama Rita El Shammas, Martin L. Tomov, Emilio A. Mendiola, Vahid Serpooshan, Reza Avazmohammadi   +7 more
wiley   +1 more source

Organoid bioinks: construction and application

Biofabrication
Abstract Organoids have emerged as crucial platforms in tissue engineering and regenerative medicine but confront challenges in faithfully mimicking native tissue structures and functions. Bioprinting technologies offer a significant advancement, especially when combined with organoid bioinks-engineered formulations designed to ...
Fuxiao Wang, Peiran Song, Jian Wang, Sicheng Wang, Yuanyuan Liu, Long Bai, Jiacan Su   +6 more
openaire   +2 more sources

Precise stacking of decellularized extracellular matrix based 3D cell-laden constructs by a 3D cell printing system equipped with heating modules [PDF]

, 2019
Three-dimensional (3D) cell printing systems allow the controlled and precise deposition of multiple cells in 3D constructs. Hydrogel materials have been used extensively as printable bioinks owing to their ability to safely encapsulate living cells ...
Ahn, Geunseon, Cho, Dong-Woo, Jin, Songwan, Kang, Donggu, Kim, Changhwan, Kim, Jun-Young, Lee, Jeong-Seok, Min, Kyung-Hyun, Shim, Jin-Hyung, Won, Joo-Yun, Yun, Won-Soo   +10 more
core   +1 more source

High-yield cell-derived extracellular matrix bioink via macromolecular crowding for versatile 3D bioprinting

Materials Today Bio
Decellularized extracellular matrix (dECM) is a promising bioink because it replicates the biochemical and structural features of native tissues. However, tissue-derived dECM is limited by restricted availability and potential immunogenicity. To overcome
Siwi Setya Utami, Honghyun Park, Jueun Kim, Aram Sung, Min-Ju Choi, Ga-Hee Ryoo, Chang Woo Gal, Insup Kim, Hui-Suk Yun, Yeong-Jin Choi   +9 more
doaj   +1 more source