Results 61 to 70 of about 9,447 (273)

Valuable effect of Manuka Honey in increasing the printability and chondrogenic potential of a naturally derived bioink

Materials Today Bio, 2022
Hydrogel-based bioinks are the main formulations used for Articular Cartilage (AC) regeneration due to their similarity to chondral tissue in terms of morphological and mechanical properties. However, the main challenge is to design and formulate bioinks
Annachiara Scalzone, Giorgia Cerqueni, Maria A. Bonifacio, Michele Pistillo, Stefania Cometa, Monica Mattioli Belmonte, Xiao N. Wang, Kenny Dalgarno, Ana M. Ferreira, Elvira De Giglio, Piergiorgio Gentile   +10 more
doaj   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

A structure-supporting, self-healing, and high permeating hydrogel bioink for establishment of diverse homogeneous tissue-like constructs

Bioactive Materials, 2021
The ready-to-use, structure-supporting hydrogel bioink can shorten the time for ink preparation, ensure cell dispersion, and maintain the preset shape/microstructure without additional assistance during printing.
Hongqing Chen, Fei Fei, Xinda Li, Zhenguo Nie, Dezhi Zhou, Libiao Liu, Jing Zhang, Haitao Zhang, Zhou Fei, Tao Xu   +9 more
doaj   +1 more source

Magnetically Driven Biofabrication for Tissue Engineering: From Nanoparticle Design to Mag‐ATMP Translation

Advanced Healthcare Materials, EarlyView.
Magnetically responsive nanoparticles enable remote control over biomaterials, cells, and engineered tissues. This review summarizes material design, biological safety, fabrication and actuation strategies, computational validation, and translational pathways that support the development of magnetic tissue‐engineering platforms and future magnetically ...
Konstantinos Ioannidis, Dimitrios Lefas, Maya Guilliams, Jackie Van Grootenbril, Isaak Decoene, Dimitrios Sakellariou, Bart Smeets, Stefanos Mourdikoudis, Ioannis Papantoniou   +8 more
wiley   +1 more source

A Hybrid Bioprinting–Microfabrication Approach to Controllable Multitype Spheroid Arrays for Modeling Tumor Heterogeneity

Advanced Healthcare Materials, EarlyView.
This work introduces a “cancer‐in‐a‐well” technology that recreates tumor heterogeneity in vitro using multitype spheroid arrays. Combining bioprinting/microdispensing with microstructured culture devices, the system improves drug screening and modeling of tumor complexity.
Simone Bonetti, Eva Clemente, Emanuela Mensà, Marco de Maria, Fulvia Farabegoli, Emanuela Saracino, Barbara Bortolani, Emanuela Marcelli, Renato Brandimarti, Dario de Biase, Giampaolo Zuccheri   +10 more
wiley   +1 more source

Three-Dimensional Bioelectrodes Utilizing Graphene Based Bioink

, 2019
Enzyme immobilization using nanomaterials offers new approaches to enhanced bioelectrochemical performance and is essential for the preparation of bioelectrodes with high reproducibility and low cost.
Zhang, Jingdong, Werchmeister, Rebecka Maria Larsen, Tang, Jing, Ulstrup, Jens, Hjuler, Hans Aage, Xiao, Xinxin, Wollenberger, Ulla   +6 more
core   +1 more source

Spatial Control of Light‐Responsive Proteins and Optogenetics Within Hydrogels via Volumetric Bioprinting

Advanced Materials, EarlyView.
Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi, Pere Català, Gabriel Größbacher, Paulina Nuñez Bernal, Olaf Nijssen, Sammy Florczak, Wilco Nijenhuis, Nuria Crusellas‐Villorbina, Bram Nijhoff, Paul Delrot, Jos Malda, Andreas Hierholzer, Martin Fussenegger, Lukas C. Kapitein, Riccardo Levato   +14 more
wiley   +1 more source

Bioprinting of 3D Tissue Models Using Decellularized Extracellular Matrix Bioink

, 2017
Bioprinting provides an exciting opportunity to print and pattern all the components that make up a tissue—cells and extracellular matrix (ECM) material—in three dimensions (3D) to generate tissue analogues. A large number of materials have been used for
Dong-Woo Cho, Cho, D.-W., Pati, Falguni, Falguni Pati, Cho, Dong-Woo, Pati, F.   +5 more
core   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Thiol-functionalized polylysine as macro antibacterial thiol-norbornene crosslinker for constructing 3D-bioprinted wound healing scaffolds

Polymer Testing
Photo-crosslinking-based 3D bioprinting is a promising approach to fabricate bioactive cell-laden scaffolds for wound healing. While thiol-ene-based bioink has been developed to fabricate 3D devices with improved gelation and bioactivity, the bacterial ...
Xiong Xiao, Hongying Duan, Qipu Feng, Yushang Lai, Fenglin Xiong, Liping Yang, Ziwei Huang, Chenxi Li, Yuchu Yang, Dan Long, Li Feng   +10 more
doaj   +1 more source