Results 61 to 70 of about 9,187 (213)

Multi‐Tissue Crosstalk Regulating Meniscus Healing Under Inflammation and Physiological Loading

Advanced Science, EarlyView.
Using a novel Meniscus‐on‐a‐chip (MoC) model integrated with a meniscus‐specific bioreactor, this study investigated the roles of multi‐tissue crosstalk that regulates injury, healing, and degeneration of the meniscus injury under inflammation and pathophysiological loading.
Hun Jin Jeong, Elen Zhu, Min Seo Kang, Ming Wang, Sam Comito, Chang H. Lee   +5 more
wiley   +1 more source

Man vs. machine: Automated bioink mixing device improves reliability and reproducibility of bioprinting results compared to human operators

The bioink mixing process is highly relevant to the bioink quality, which is the basis for reproducible extrusion-based three-dimensional (3D) bioprinting (EBB).
Pang, Shumin, Röhrs, Viola, Ziersch, Mathias, Wu, Dongwei, Ali, Ahmed S. M., Mei, Yikun, Tolksdorf, Beatrice, Berg, Johanna, Kurreck, Jens   +8 more
core   +1 more source

Extrusion of Cell Encapsulated in Boron Nitride Nanotubes Reinforced Gelatin—Alginate Bioink for 3D Bioprinting

, 2022
Three-dimensional (3D) bioprinting, an innovative technology, has gained the attention of researchers as a promising technique for the redevelopment of complex tissue or organ structures.
Ing Kong (9481514), Akesh Babu Kakarla (9491567), Helen Irving (8310519), Colleen Thomas (9481427), Cin Kong (9990239)   +4 more
core   +1 more source

Advancing Biotherapeutic Treatment of Ulcerative Colitis Using Lipid Mesophases: Formulation Design and Preclinical Validation

Advanced Science, EarlyView.
Lipid mesophases provide a versatile platform for colon‐targeted delivery of biotherapeutics, protecting them from degradation while enhancing mucoadhesion and enabling localized, controlled release to the inflamed mucosa after oral or rectal administration. In a DSS‐induced colitis model, this strategy reduced disease activity, inflammatory biomarkers,
Rafaela Gazzi, Tiziana Cremona, Reto Czekalla, Emily Campbell, Marlene Schwarzfischer, Doris Pöhlmann, Vanessa Dobernig, Gerhard Rogler, Michael Scharl, Alessandra Bergadano, Raffaele Mezzenga, Martin Kuentz, Paola Luciani, Simone Aleandri   +13 more
wiley   +1 more source

Tailoring mechanical properties of decellularized extracellular matrix bioink by vitamin B2-induced photo-crosslinking

, 2018
We have developed two-step process that uses sequential vitamin B2-induced UVA crosslinking and thermal gelation to solidify decellularized extracellular matrix (dECM) bioink; this process enables tailoring of mechanical properties of 3D-printed ...
Kim, BS, Kim, TG, Kim, SW, Kwon, SM, Jang, J, Cho, DW   +5 more
core   +1 more source

Bioinks of Natural Biomaterials for Printing Tissues

Bioengineering, 2023
Bioinks are inks—in other words, hydrogels—prepared from biomaterials with certain physiochemical properties together with cells to establish hierarchically complex biological 3D scaffolds through various 3D bioprinting technologies [...]
openaire   +3 more sources

µSlicer for Programmable Multimaterial 3D Printing

Advanced Science, EarlyView.
ABSTRACT Nature rarely builds with uniform materials; instead, it achieves exceptional performance by arranging composition and structure across multiple length scales. Mimicking such architectures has become increasingly feasible with additive manufacturing, and especially with multimaterial 3D printing, where complex structures with spatially varying
Daniel H. Meile, Berin Šeta, Md. Tusher Mollah, Yohan Jacquet, Rob Wolfs, Jon Spangenberg   +5 more
wiley   +1 more source

Microfluidic Bioprinting of Heterogeneous 3D Tissue Constructs Using Low-Viscosity Bioink

, 2016
A novel bioink and a dispensing technique for 3D tissue-engineering applications are presented. The technique incorporates a coaxial extrusion needle using a low-viscosity cell-laden bioink to produce highly defined 3D biostructures. The extrusion system
Dokmeci, Mehmet Remzi, Cristina Colosi, Andrea Barbetta, Solange Massa, Manoharan, Vijayan, Massa, Solange, Ali Khademhosseini, Barbetta, Andrea, Dentini, Mariella, Khademhosseini, Ali, Mehmet Remzi Dokmeci, Su Ryon Shin, Mariella Dentini, Vijayan Manoharan, Costantini, Marco, Shin, Su Ryon, Marco Costantini, Colosi, Cristina   +17 more
core   +1 more source

Engineering a Bioelectronic Hybrid Heart with Integrated Sensing and Electrical Modulation

Advanced Science, EarlyView.
A bioelectronic hybrid heart is engineered by integrating iPSC‐derived cardiomyocytes, a decellularized cardiac scaffold, a cell‐laden ECM coating, and a flexible electronic mesh. The embedded electrodes enable real‐time recording of spontaneous electrical activity and localized stimulation, allowing controlled pacing and modulation of activation ...
Itai Cabilly, Hadas Oved, Ron Feiner, Nadav Noor, Moran Yadid, Melanie Flury, Assaf Shapira, Tal Dvir   +7 more
wiley   +1 more source

Silk Fibroin for Cardiovascular Medical Devices: Review of Material Properties, Applications, and Clinical Potential

Advanced NanoBiomed Research, EarlyView.
Silk fibroin is an attractive natural biomaterial that can be engineered into diverse cardiovascular constructs, including vascular grafts, cardiac patches, heart valves, and stent coatings. Its tunable biological and mechanical properties have driven substantial preclinical progress; however, widespread clinical translation in cardiovascular ...
Mahsa Haghighattalab, Matt Govendir, Kristina Andelovic, Zachary Och, Fatemeh Karimi, Munira Xaymardan, Tomasz Jungst, Jelena Rnjak‐Kovacina, Nona Farbehi   +8 more
wiley   +1 more source