Results 111 to 120 of about 8,588 (257)

Comparative assessment of volume‐of‐fluid (VOF) multiphase solvers for viscoplastic flow over grooved patterned surfaces

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Accurately simulating multiphase flows at low capillary numbers remains challenging due to spurious currents and interface discretization errors. We present a systematic comparison of four volume‐of‐fluid (VOF) solvers within the OpenFOAM framework for pressure‐driven Poiseuille–Bingham flow over grooved surfaces: interFoam with classical ...
Amir Joulaei, Alice Villette, Seyed Mohammad Taghavi   +2 more
wiley   +1 more source

A Deep Learning Pipeline for Cell Segmentation and Viability Quantification in 3D Constructs From Fluorescence Microscopy Images

Microscopy Research and Technique, EarlyView.
3D bioprinting requires advanced methods for cell localization and viability assessment. We developed a hybrid and automated pipeline based on the U2‐Net architecture for the analysis of fluorescence microscopy images enabling cell segmentation and viability assessment.
Federica Valtellina, Francesco Iannacci, Bianca Maria Colosimo, Mattia Sponchioni   +3 more
wiley   +1 more source

Organoid Coculture Models for Cancer Research and Immunotherapy

Med Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang, Huihui Yang, Guangxin Li, Guobang Liu, Zhulan Chen, Wenzhi Tian, Meiyang Huang, Xiaoling Liu, Yongsheng Zhao, Dong Chen   +9 more
wiley   +1 more source

3D Bioprinted Neural Tissues: Emerging Strategies for Regeneration and Disease Modeling

Pharmaceutics
Three-dimensional (3D) bioprinting has emerged as a versatile platform in regenerative medicine, capable of replicating the structural and functional intricacies of the central and peripheral nervous systems (CNS and PNS).
Taekyung Choi, Jinseok Park, Suvin Lee, Hee-Jae Jeon, Byeong Hee Kim, Hyun-Ouk Kim, Hyungseok Lee   +6 more
doaj   +1 more source

A Simple Rheology‐Based Framework for Selecting Printing Parameters in Extrusion‐Based Hydrogel Additive Manufacturing

Polymer Engineering &Science, EarlyView.
An open analytical framework converts standard rheological measurements directly into the complete extrusion field and slicer‐ready printing parameters for Piston driven printers, enabling rapid operational window of printability in direct ink writing without CFD or machine learning. ABSTRACT Predicting whether a gel formulation will print successfully
Thiago M. C. Rodrigues, João V. R. C. dos Santos, Nicole P. Martins, Rossana Mara da Silva Moreira Thiré   +3 more
wiley   +1 more source

Transformation of the Biological Paradigm in Bone Regeneration: An Integrative Review

Journal of Developmental Biology
Bone tissue is among the most commonly transplanted tissues worldwide. The treatment of critical-sized bone defects remains a significant challenge, as there is currently no universally accepted experimental model or therapeutic standard. Recent advances
Diyana Vladova
doaj   +1 more source

Current Trends and Future Prospects of Integrating Electrospinning With 3D Printing Techniques for Mimicking Bone Extracellular Matrix Scaffolds

Journal of Polymer Science, Volume 63, Issue 6, Page 1481-1504, 15 March 2025.
ABSTRACT This article presents a review of the recent findings on the combination of electrospun nanofibers and three‐dimensional (3D)‐printed structures for extracellular matrix (ECM) scaffolds for bone tissue engineering. We explore the synergy between electrospinning (ES), which produces highly porous, fibrous structures from materials like collagen
Kardo Khalid Abdullah, Kolos Molnár
wiley   +1 more source

Next-Generation Bioinks in 3D Bioprinting: Advances, Challenges, and Emerging Opportunities

3D bioprinting is an innovative technology that has advanced the field of tissue engineering and regenerative medicine by allowing the layer-by-layer deposition of cells, biomaterials, and bioactive molecules to create sophisticated biological constructs.
Shruti R. Balkawade, Usha Y. Nayak, Devika Sajeev   +2 more
core   +1 more source

Microfluidic Capillary Arrays for Pixelated Control of Multimaterial Flows

Small, EarlyView.
A 3D‐printed pixellated capillary array maps up to thousands of fluid inputs into arbitrary multimaterial flow cross‐sections. Automated manifold design and laminar scaling are used to amplify printing resolution orders of magnitude, generating microscale fluidic control from printed elements, enabling designed microflows for potential use in ...
Max Chapman, Muhammad Utomo, David J. Collins   +2 more
wiley   +1 more source

In Vitro Functional and Structural Evaluation of Low-Complexity Artificial Human Epidermis for 3D Tissue Engineering

Bioengineering
In recent times, with the need for a reduction, refinement, and replacement of in vivo animal testing, there has been an increasing demand for the use of relevant in vitro human cell systems in drug development.
Dorottya Kocsis, Dániel Sztankovics, Liza Józsa, Afrodité Németh, Tamás Garay, Márton Bese Naszlady, Miléna Lengyel, Miklós Vecsernyés, István Antal, Anna Sebestyén, Franciska Erdő   +10 more
doaj   +1 more source