Results 91 to 100 of about 5,714 (206)

Fabrication of gelatin-heparin based cartilage models: enhancing spatial complexity through refinement of stiffness properties and oxygen availability

Frontiers in Biomaterials Science
The intricate nature of native cartilage, characterized by zonal variations in oxygen levels and ECM composition, poses a challenge for existing hydrogel-based tissue models. Consequently, these 3D models often present simplified renditions of the native
G. Lindberg, G. Lindberg, A. Norberg, B. Soliman, T. Jüngst, K. Lim, K. Lim, G. Hooper, J. Groll, T. Woodfield   +9 more
doaj   +1 more source

E. coli Extracellular Matrix: A Tunable Composite With Hierarchical Structure

Advanced Materials, Volume 38, Issue 43, 3 August 2026.
The complex composite‐like mechanical behavior of E. coli biofilm matrix is the result of a synergic contribution of the rigid curli and swelling pEtN‐cellulose, and emerges from specific ratio and assembly conditions. The interactions between the two fibers govern biofilm hydration and characteristic wrinkling patterns, providing crucial insights for ...
Macarena Siri, Agustín Mangiarotti, Anne Seewald, Nikolai Rosenthal, Shahrouz Amini, Emeline Raguin, Peter Fratzl, Cécile M. Bidan   +7 more
wiley   +1 more source

Narrative Review and Guide: State of the Art and Emerging Opportunities of Bioprinting in Tissue Regeneration and Medical Instrumentation

Bioengineering
Three-dimensional printing was introduced in the 1980s, though bioprinting started developing a few years later. Today, 3D bioprinting is making inroads in medical fields, including the production of biomedical supplies intended for internal use, such as
Jaroslava Halper
doaj   +1 more source

Challenging the Status Quo: Standardisation, Regulation and the Rise of 3D In Vitro Models for a More Humane and Predictive Future in Healthcare

Advanced Therapeutics, Volume 9, Issue 8, August 2026.
Overview of challenges in traditional models and how 3D in vitro models and in silico approaches tackle those, incentivising a collaboration between what is currently an accepted standard, validated and regulated, with the new technologies to ensure faster adoption and translation. (Created with BioRender). ABSTRACT For decades, biomedical research has
Priscila Melo
wiley   +1 more source

Three-Dimensional Bioprinting for Retinal Tissue Engineering

Biomimetics
Three-dimensional bioprinting (3DP) is transforming the field of regenerative medicine by enabling the precise fabrication of complex tissues, including the retina, a highly specialized and anatomically complex tissue. This review provides an overview of
Kevin Y. Wu, Rahma Osman, Natalie Kearn, Ananda Kalevar   +3 more
doaj   +1 more source

3D Printing Beyond Conventional Rheological Limits: Two‐Step Crosslinking of Low‐Viscosity/Moduli Inks Into Tough Hydrogels

Chemistry–Methods, Volume 6, Issue 8, August 2026.
In this work, we introduced a two‐step crosslinking strategy that enables the printing of inks with poor rheological properties into robust, free‐standing hydrogel structures. These inks are unable to retain their shape after printing. Through the proposed crosslinking approach, they not only preserve their printed geometry but also form self ...
Asal Jaberansari, Rokhsareh Bakhtiari, Shakiba Samsami, Monica Ho, Majed Amini, Milad Kamkar   +5 more
wiley   +1 more source

Active Media Perfusion in Bioprinted Highly Concentrated Collagen Bioink Enhances the Viability of Cell Culture and Substrate Remodeling

Gels
The bioprinting of high-concentrated collagen bioinks is a promising technology for tissue engineering and regenerative medicine. Collagen is a widely used biomaterial for bioprinting because of its natural abundance in the extracellular matrix of many ...
Denisa Kanokova, Roman Matejka, Margit Zaloudkova, Jan Zigmond, Monika Supova, Jana Matejkova   +5 more
doaj   +1 more source

Liquid Crystal Elastomers Filaments for Adaptive Textiles and Soft Robotics: A Processing‐Centric Review

Macromolecular Rapid Communications, Volume 47, Issue 15, 4 August 2026.
Liquid crystal elastomer (LCE) filaments are fabricated through extrusion with in‐process UV curing, enabling controlled flow alignment and network locking of mesogens. The resulting structure responds to thermal or optical stimuli, inducing molecular reorientation and macroscopic contraction.
Anne Schwarz‐Pfeiffer, Shazia Mehtab
wiley   +1 more source

Injectable Short Nanofiber Fragments Enable Conformal Fibrous Scaffolds for Tissue Engineering on Complex Surfaces

Macromolecular Rapid Communications, Volume 47, Issue 15, 4 August 2026.
Short nanofiber fragments (SNFs) derived from electrospun PDLA/gelatin (PG) mats dynamically reassemble into conformal fibrous networks on complex substrates. This approach overcomes the geometric limitations of conventional electrospinning, enabling uniform surface coverage, enhanced wettability, and cytocompatible scaffold formation, thereby offering
Iruthayapandi Selestin Raja, Hee Jeong Jang, Elif Beyza Demiray, Dongwoo Gi, Suong‐Hyu Hyon, Yuki Gen, Bongju Kim, Dong‐Wook Han   +7 more
wiley   +1 more source

3D Liver Fibrosis Models in Lab: A Novel Modality for Drug Screening

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Liver fibrosis is the common consequence of liver injury caused by a variety of chronic liver disorders. This condition leads to the development of more severe complications, particularly cirrhosis and hepatocellular carcinoma. Despite abundant studies, the fundamental cell and molecular mechanisms of liver fibrosis are still unknown.
Hani Keshavarz Alikhani, Fatemeh Majidi, Mahsa Ghasemzad, Anastasia Shpichka, Anastasia Nestorova, Zahra Hendi, Elham Rismani, Daria Kuznetsova, Peter Timashev, Massoud Vosough, Abbas Piryaei   +10 more
wiley   +1 more source