Results 91 to 100 of about 7,581 (247)

Generation of Self‐Organizing Macrovascular Constructs by Bioprinting Human iPSC‐Derived Mesodermal Progenitor Cells

open access: yesAdvanced Science, EarlyView.
ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Leyla E. Dogan   +5 more
wiley   +1 more source

Beyond Potency: Emerging Determinants and Optimization Strategies Enhancing Therapeutic Efficacy of Adult Stem Cells

open access: yesAdvanced Science, EarlyView.
Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim   +2 more
wiley   +1 more source

Pore-forming bioinks to enable spatio-temporally defined gene delivery in bioprinted tissues

open access: yes, 2022
The regeneration of complex tissues and organs remains a major clinical challenge. With a view towards bioprinting such tissues, we developed a new class of pore-forming bioink to spatially and temporally control the presentation of therapeutic genes ...
Nicholas J. Dunne (7309871)   +10 more
core   +1 more source

New opportunities for bioscaffold‐enabled spinal cord injury repair

open access: yesBMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi   +11 more
wiley   +1 more source

Marine silicon for biomedical sustainability

open access: yesBMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han   +3 more
wiley   +1 more source

Hydrogel-Colloid Composite Bioinks for Targeted Tissue-Printing

open access: yes, 2020
International audienceThe development of extrusion-based bioprinting for tissue engineering is conditioned by the design of bioinks displaying adequate printability, shape stability, and postprinting bioactivity.
Auzély-Velty, Rachel   +3 more
core   +1 more source

From Bioinks to Functional Tissues and Organs: Advances, Challenges, and the Promise of 3D Bioprinting

open access: yesMacromolecular Materials and Engineering
3D printing, particularly bioprinting, has emerged as a transformative technology in tissue engineering and regenerative medicine, enabling the precise layer‐by‐layer fabrication of living tissues and complex biomaterials. Bioprinting has evolved through
Muhammad Wajid Ullah   +9 more
doaj   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

open access: yesBMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma   +8 more
wiley   +1 more source

Nanometric Hydroxyapatite Particles as Active Ingredient for Bioinks: A Review

open access: yes, 2022
Additive manufacturing (AM), frequently cited as three-dimensional (3D) printing, is a relatively new manufacturing technique for biofabrication, also called 3D manufacture with biomaterials and cells.
Virginia Sáez-Martínez   +5 more
core   +1 more source

Polymeric hydrogel nanoparticles in drug delivery and bioprinting technologies: a review

open access: yesMGM Journal of Medical Sciences
Multiple kinds of hydrogel polymers, natural and synthetic, are known. Self-assembly and aggregation are their inherent properties. The diverse applications of hydrogel polymers, encompassing natural and synthetic varieties known for their water-swelling
Prasanta Kumar Ghosh
doaj   +1 more source

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