Results 71 to 80 of about 8,588 (257)

Extrusion bioprinting of elastin‐containing bioactive double‐network tough hydrogels for complex elastic tissue regeneration

Aggregate
Despite recent advances in extrusion bioprinting of cell‐laden hydrogels, using naturally derived bioinks to biofabricate complex elastic tissues with both satisfying biological functionalities and superior mechanical properties is hitherto an unmet ...
Di Wang, Jinshi Zeng, Hailin Zhu, Siyu Liu, Litao Jia, Wenshuai Liu, Qian Wang, Senmao Wang, Wei Liu, Jiayu Zhou, Huimin Chen, Xia Liu, Haiyue Jiang   +12 more
doaj   +1 more source

Organoid bioinks: construction and application

Biofabrication
Abstract Organoids have emerged as crucial platforms in tissue engineering and regenerative medicine but confront challenges in faithfully mimicking native tissue structures and functions. Bioprinting technologies offer a significant advancement, especially when combined with organoid bioinks-engineered formulations designed to ...
Fuxiao Wang, Peiran Song, Jian Wang, Sicheng Wang, Yuanyuan Liu, Long Bai, Jiacan Su   +6 more
openaire   +2 more sources

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Bioprinted Hydrogels as Vehicles for the Application of Extracellular Vesicles in Regenerative Medicine

Gels
Three-dimensional bioprinting is a new advance in tissue engineering and regenerative medicine. Bioprinting allows manufacturing three-dimensional (3D) structures that mimic tissues or organs.
Marta Camacho-Cardenosa, Victoria Pulido-Escribano, Guadalupe Estrella-Guisado, Gabriel Dorado, Aura D. Herrera-Martínez, María Ángeles Gálvez-Moreno, Antonio Casado-Díaz   +6 more
doaj   +1 more source

Sustainable Fabrication of Tailored Bone Substitutes: From High‐Throughput Scaffold Manufacturing, Scaled‐Up HMSC Expansion to Dynamic Cultivation in a Perfusion Bioreactor

Advanced Science, EarlyView.
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun, Anna Paříková, Sandra Rother, Martin Kantor, Salman Muhammad Ilyas, Ricardo Bernhardt, Pavel Ndjawa Yomi, Jaromír Havlica, Revathi Appali, Benjamin Kruppke, Poh Soo Lee   +10 more
wiley   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Prospects of emerging 3D bioprinting technologies: major technology components, technology developers, and end users—Part I

MGM Journal of Medical Sciences
Bioprinting technology aims to create 3D structures with living cells to mimic real tissue and organ functions. The process involves various additive technologies, including 3D bioprinters and bioinks.
Prasanta K. Ghosh
doaj   +1 more source

A definition of bioinks and their distinction from biomaterial inks [PDF]

, 2018
Biofabrication aims to fabricate biologically functional products through bioprinting or bioassembly (Groll et al 2016 Biofabrication 8 013001). In biofabrication processes, cells are positioned at defined coordinates in three-dimensional space using ...
Nakayama, K, Juengst, T., Nakayama, K., Burdick, J. A., Heilshorn, S C, Cho, D. W., Takeuchi, S, Cho, D-W, Derby, B, Gelinsky, M, Mironov, V A, Takeuchi, S., Burdick, J A, Heilshorn, S. C., Malda, J., Groll, J, LS Equine Muscoskeletal Biology, dES RMSC, Mironov, V. A., Woodfield, T. B.F., Derby, B.; id_orcid, Yoo, J J, Ovsianikov, A, Ovsianikov, A., Derby, B., Gelinsky, M., Malda, J, Sun, W, Jüngst, T., Woodfield, T B F, Sun, W., Groll, J., Jüngst, T, Yoo, J. J., Woodfield, T. B. F.   +34 more
core   +3 more sources

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Development of nanocellulose-hyaluronic acid bioinks for 3D bioprinting facial cartilages

Carbohydrate Polymer Technologies and Applications
Nanocellulose (NC) possesses desirable biological and mechanical properties for 3D bioprinting. This study aimed to derive a novel NC-hyaluronic acid (HA) bioink for 3D bioprinting facial cartilages and assess its printability, biocompatibility and ...
Thomas H Jovic, Andrea Gazze, Bethan Morgan, Karl Hawkins, Lewis Francis, Hari Arora, Shareen H Doak, Iain S Whitaker   +7 more
doaj   +1 more source