Results 71 to 80 of about 9,027 (246)

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Bioprinted Hydrogels as Vehicles for the Application of Extracellular Vesicles in Regenerative Medicine

Gels
Three-dimensional bioprinting is a new advance in tissue engineering and regenerative medicine. Bioprinting allows manufacturing three-dimensional (3D) structures that mimic tissues or organs.
Marta Camacho-Cardenosa, Victoria Pulido-Escribano, Guadalupe Estrella-Guisado, Gabriel Dorado, Aura D. Herrera-Martínez, María Ángeles Gálvez-Moreno, Antonio Casado-Díaz   +6 more
doaj   +1 more source

Heat‐Suppressing Projection Two‐Photon Lithography Enables High‐Throughput Sub‐Micrometer Manufacturing of Biopolymer Hydrogels for Tissue Engineering

Advanced Science, EarlyView.
The iLEAP technique integrates high‐throughput two‐photon lithography with extrusion printing, bridging sub‐micrometer precision and macroscopic scaffold fabrication. By employing a low‐exothermic photoinitiator, it mitigates thermal damage to biopolymers and preserves bioactivity.
Qifeng Guan, Yanzhe Fu, Xiangyu Xu, Naitao Li, Sen Hou, Kai Wang, Yufan Wang, Jiakun Li, Ping Li, Jiebo Li, Lizhen Wang, Yubo Fan   +11 more
wiley   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Printable Piezoresistive Hybrid Hydrogels Based on 2D MoS2 for Flexible Pulse Sensing

Advanced Science, EarlyView.
Hybrid 1T‐MoS2‐based hydrogels are engineered through UV curing and 3D printing to achieve tunable electromechanical properties for wearable sensing. These soft architectures enhance mechanical stability and reproducible piezoresistive responses within the physiological pressure range.
Jenny Flores, Arianna Bertero, Luca Ceseracciu, Daniel Jiménez‐Boland, Sara Domenici, Mattia Bramini, Paola Sánchez‐Moreno, Erica Scarcelli, Domenico Galdiero, Pavel Fedorov, Daniil Karnaushenko, Rossella Sesia, Ignazio Roppolo, Micaela Pozzati, Mattia Spedicati, Nicolò Petrini, Marco Sangermano, Bartolomeo Coppola, Teresa Gatti   +18 more
wiley   +1 more source

Prospects of emerging 3D bioprinting technologies: major technology components, technology developers, and end users—Part I

MGM Journal of Medical Sciences
Bioprinting technology aims to create 3D structures with living cells to mimic real tissue and organ functions. The process involves various additive technologies, including 3D bioprinters and bioinks.
Prasanta K. Ghosh
doaj   +1 more source

Development of nanocellulose-hyaluronic acid bioinks for 3D bioprinting facial cartilages

Carbohydrate Polymer Technologies and Applications
Nanocellulose (NC) possesses desirable biological and mechanical properties for 3D bioprinting. This study aimed to derive a novel NC-hyaluronic acid (HA) bioink for 3D bioprinting facial cartilages and assess its printability, biocompatibility and ...
Thomas H Jovic, Andrea Gazze, Bethan Morgan, Karl Hawkins, Lewis Francis, Hari Arora, Shareen H Doak, Iain S Whitaker   +7 more
doaj   +1 more source

Application and Single‐Cell Regulation Mechanism of Engineered EVs Combined With 4D‐Printed Hydrogel for Infected Burn Repair

Advanced Science, EarlyView.
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang, Xiaoyan Li, Xiao Xu, Kelun Zhang, Fengjiao Yu, Zhen Shang, Nailong Pan, Junlin Lv, Yiwei Xu, Yan Tang, Liang Zhang, Xiaotong Li, Taoyi Wang, Jing Tao, Jiaxu Song, Mengyu Zhang, Xin Ma, Dan Han, Xiaoying Kong, Wenhua Xu   +19 more
wiley   +1 more source

In Vitro Functional and Structural Evaluation of Low-Complexity Artificial Human Epidermis for 3D Tissue Engineering

Bioengineering
In recent times, with the need for a reduction, refinement, and replacement of in vivo animal testing, there has been an increasing demand for the use of relevant in vitro human cell systems in drug development.
Dorottya Kocsis, Dániel Sztankovics, Liza Józsa, Afrodité Németh, Tamás Garay, Márton Bese Naszlady, Miléna Lengyel, Miklós Vecsernyés, István Antal, Anna Sebestyén, Franciska Erdő   +10 more
doaj   +1 more source

Matrix metalloproteinase degradable, in situ photocrosslinked nanocomposite bioinks for bioprinting applications

, 2023
The development of suitable bioinks with high printability, mechanical strength, biodegradability, and biocompatibility is a key challenge for the clinical translation of 3D constructs produced with bioprinting technologies.
Teixeira, Filipa Castro, Aygul Zengin, Filipa Castro Teixeira, Habibovic, Pamela; id_orcid, Mota, Carlos Domingues; id_orcid, Feliciano, Tony, Zengin, Aygul, Matthew B. Baker, Carlos Domingues Mota, Tony Feliciano, Sabine van Rijt, Pamela Habibovic, van Rijt, Sabine; id_orcid, Baker, Matthew B.; id_orcid   +13 more
core   +1 more source