Results 31 to 40 of about 894,684 (203)

Mesenchymal Stromal Cell‐Based Cell–Drug Conjugates for the Treatment of Acute Liver Failure

Advanced Science, EarlyView.
Mesenchymal stromal cell (MSC)‐based cell‐drug conjugates are constructed by anchoring rosiglitazone‐loaded nanoparticles onto the MSC surface. Sustained rosiglitazone release enhances MSC proliferation and paracrine activity while promoting anti‐inflammatory macrophage polarization.
Tenghui Ye, Jiamin Wu, Zixin Wu, Xi Liu, Jiajia Luo, Leyi Yang, Peng Shi   +6 more
wiley   +1 more source

Thioredoxin is required for deoxyribonucleotide pool maintenance during S phase

, 2006
J Biol ChemThioredoxin was initially identified by its ability to serve as an electron donor for ribonucleotide reductase in vitro. Whether it serves a similar function in vivo is unclear.
Wheeler, Linda J., Gross, Michael K., Mathews, Christopher K., Merrill, Gary F., Koç, Ahmet   +4 more
core   +1 more source

Correction to: Evaluating the protective potency of Acacia hydaspica R. Parker on histological and biochemical changes induced by Cisplatin in the cardiac tissue of rats

BMC Complementary Medicine and Therapies, 2020
An amendment to this paper has been published and can be accessed via the original article.
Tayyaba Afsar, Suhail Razak, Ali Almajwal, Maria Shabbir, Muhammad Rashid Khan   +4 more
doaj   +1 more source

Chemotherapy‐Activated GSK3β‐DNMT1 Signaling Upregulates CD47 to Evade Macrophage Phagocytosis and Drive Temozolomide Resistance in Glioblastoma

Advanced Science, EarlyView.
Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li, Shuai Ying, Yi Zhang, Jingjing Wang, Quan Wan, Lingli Gong, Daxing Xu, Zhenkun Yang, Hongnian Lu, Ying Yin, Xiangming Fang, Zhening Pu   +11 more
wiley   +1 more source

CRISPR-Cas9 Protocol for Efficient Gene Knockout and Transgene-free Plant Generation

Bio-Protocol
Gene editing technologies have revolutionized plant molecular biology, providing powerful tools for precise gene manipulation for understanding function and enhancing or modifying agronomically relevant traits.
Enzo Perk, Ana Laxalt, Ignacio Cerrudo
doaj   +1 more source

Niveles de biol bovino en la recuperación de una pradera nativa en condición de ladera

Revista de Investigación e Innovación Agropecuaria y de Recursos Naturales
La diversidad de pastos de las praderas nativas que se desarrollan en las pampas, laderas y sierras, en diferentes altitudes del altiplano, constituyen el alimento básico del ganado de altura.
Alain Hanz Arcón Bando, Zenón Martínez Flores, Lizett Kattya Martínez Luizaga   +2 more
doaj   +1 more source

Evaluación de la macroalga Ulva lactuca como aportante de nutrientes a un inóculo metanogénico en la producción de biogás y biol mediante digestión anaerobia de residuos orgánicos del comedor de la UNALM

Revista del Instituto de Investigación de la Facultad de Minas, Metalurgia y Ciencias Geográficas, 2016
La presente investigación tuvo como objetivo la evaluación del desempeño de la Ulva lactuca en la producción de biogás y biol, analizando su interacción con contenido ruminal vacuno, para lo cual se usó residuos orgánicos del comedor universitario de la ...
Melissa Capcha Eulogio, Lawrence Quipuzco Ushñahua, Víctor Meza Contreras   +2 more
doaj   +1 more source

Single‐cell RNA sequencing of peripheral blood defines two immunological subtypes of Sjögren's disease distinguished by anti‐SSA antibodies and aberrant B cell populations

Arthritis &Rheumatology, Accepted Article.
Objectives Sjögren's disease (SjD) is a heterogeneous autoimmune disorder characterized by substantial clinical and molecular diversity. This heterogeneity raises key questions regarding the existence of distinct pathogenic mechanisms underlying disease subtypes.
Geoffrey Urbanski, Kimberly E. Taylor, Emily Flynn, Armita Norouzi, Catherine Chu, Brittany Davidson, Arnab Ghosh, Joanne Nititham, Ravi K. Patel, Annie W. Poon, Gabriela K. Fragiadakis, Alexis J. Combes, Walter L. Eckalbar, Lindsey A. Criswell, Chun Jimmie Ye, Caroline H. Shiboski   +15 more
wiley   +1 more source

Transcriptomic Profiling in Skeletal Muscle Identifies Associations With Knee Osteoarthritis: the Study of Muscle, Mobility and Aging (SOMMA)

Arthritis &Rheumatology, Accepted Article.
Objectives The association between skeletal muscle gene expression and knee osteoarthritis (OA) was examined among older adult participants of the Study of Muscle, Mobility and Aging (SOMMA). Methods Inclusion criteria included knee radiographs and bulk RNA sequencing (RNAseq) in vastus lateralis muscle, resulting in 523 participants (56% female ...
Daniel S. Evans, Tyler A. Mansfield, Gina M. Many, Tyler J. Sagendorf, Samaneh Farsijani, Bret H. Goodpaster, Lauren M. Sparks, Nancy E. Lane   +7 more
wiley   +1 more source

De Estiércol a Energía - Captura de Metano en Ecuador

Revista Tecnológica, 2011
Este proyecto intenta demostrar los posibles beneficios ambientales y económicos del uso de digestión anaeróbica para el tratamiento de estiércol animal en el Ecuador.
Camilo Cornejo, Ann C. Wilkie
doaj   +4 more sources