Results 31 to 40 of about 437,770 (246)
Contrariando la concepción etiológica de las funciones biológicas, se pretende mostrar que las explicaciones por selección natural, lejos de justificar atribuciones funcionales, las presuponen; y que estas atribuciones pueden ser entendidas apelando a ...
Gustavo Caponi
doaj +2 more sources
Steroid profiling in male wobbler mouse, a model of Amyotrophic Lateral Sclerosis [PDF]
The Wobbler mouse is an animal model for human motoneuron diseases, especially amyotrophic lateral sclerosis (ALS), used in the investigation of both pathology and therapeutic treatment.
Aprahamian, Fanny +9 more
core +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
“Avispa de la agalla del eucalipto”, Leptocybe invasa Fischer & Lasalle (Hymenoptera: Eulophidae: Tetrastichinae), en Argentina [PDF]
La “avispa de la agalla del eucalipto”, Leptocybe invasa Fischer & Lasalle (Hymenoptera: Eulophidae: Tetrastichinae) ha sido registrada en varios países como una importante plaga forestal.
AQUINO, D.A. +3 more
doaj
Dataset of the transcribed 45S ribosomal RNA sequence of the tree crop yerba mate [PDF]
This contribution contains data related to the research article entitled The 18S-25S ribosomal RNA unit of yerba mate (Ilex paraguariensis A. St.-Hil.) (Aguilera et al., 2016).
Aguilera, Patricia Mabel +2 more
core +2 more sources
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
The dual nature of trehalose in citrus canker disease: A virulence factor for Xanthomonas citri subsp. citri and a trigger for plant defence responses [PDF]
Xanthomonas citri subsp. citri (Xcc) is a bacterial pathogen that causes citrus canker in susceptible Citrus spp. The Xcc genome contains genes encoding enzymes from three separate pathways of trehalose biosynthesis.
Feil, Regina +10 more
core +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Comportamiento en el desarrollo de todos los descendientes de una pareja de Bufo arenarum
La muestra observada consistió en 1443 renacuajos nacidos el 24 de septiembre de 1962 de una pareja de sapos. El 21,4 % de la población total se encontraba inhibido en su desarrollo.
N. Guiñazú
doaj
Generation of Competences Based on the Management of Scientific Knowledge
Currently, viable alternatives are needed to improve the learning process in students and can cope with the demands of society. Generate significant experiences based on research projects of real problems, will encourage students to develop skills that ...
José Antonio Martínez Villalba +1 more
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