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ANÁLISIS FUNCIONALES Y EXPLICACIONES SELECCIONALES EN BIOLOGÍA. UNA CRÍTICA DE LA CONCEPCIÓN ETIOLÓGICA DEL CONCEPTO DE FUNCIÓN

open access: yesIdeas y Valores, 2010
Contrariando la concepción etiológica de las funciones biológicas, se pretende mostrar que las explicaciones por selección natural, lejos de justificar atribuciones funcionales, las presuponen; y que estas atribuciones pueden ser entendidas apelando a ...
Gustavo Caponi
doaj   +2 more sources

Steroid profiling in male wobbler mouse, a model of Amyotrophic Lateral Sclerosis [PDF]

open access: yes, 2016
The Wobbler mouse is an animal model for human motoneuron diseases, especially amyotrophic lateral sclerosis (ALS), used in the investigation of both pathology and therapeutic treatment.
Aprahamian, Fanny   +9 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

“Avispa de la agalla del eucalipto”, Leptocybe invasa Fischer & Lasalle (Hymenoptera: Eulophidae: Tetrastichinae), en Argentina [PDF]

open access: yesRIA: Revista Investigaciones Agropecuarias, 2011
La “avispa de la agalla del eucalipto”, Leptocybe invasa Fischer & Lasalle (Hymenoptera: Eulophidae: Tetrastichinae) ha sido registrada en varios países como una importante plaga forestal.
AQUINO, D.A.   +3 more
doaj  

Dataset of the transcribed 45S ribosomal RNA sequence of the tree crop yerba mate [PDF]

open access: yes, 2017
This contribution contains data related to the research article entitled The 18S-25S ribosomal RNA unit of yerba mate (Ilex paraguariensis A. St.-Hil.) (Aguilera et al., 2016).
Aguilera, Patricia Mabel   +2 more
core   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

The dual nature of trehalose in citrus canker disease: A virulence factor for Xanthomonas citri subsp. citri and a trigger for plant defence responses [PDF]

open access: yes, 2015
Xanthomonas citri subsp. citri (Xcc) is a bacterial pathogen that causes citrus canker in susceptible Citrus spp. The Xcc genome contains genes encoding enzymes from three separate pathways of trehalose biosynthesis.
Feil, Regina   +10 more
core   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Comportamiento en el desarrollo de todos los descendientes de una pareja de Bufo arenarum

open access: yesActa Zoológica Lilloana, 2022
La muestra observada consistió en 1443 renacuajos nacidos el 24 de septiembre de 1962 de una pareja de sapos. El 21,4 % de la población total se encontraba inhibido en su desarrollo.
N. Guiñazú
doaj  

Generation of Competences Based on the Management of Scientific Knowledge

open access: yesRevista Iberoamericana sobre Calidad, Eficacia y Cambio en Educación, 2018
Currently, viable alternatives are needed to improve the learning process in students and can cope with the demands of society. Generate significant experiences based on research projects of real problems, will encourage students to develop skills that ...
José Antonio Martínez Villalba   +1 more
doaj   +1 more source

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