Results 61 to 70 of about 310,970 (312)

Patient Preferences for Attributes of Biologic Treatments in Moderate to Severe Asthma: A Discrete Choice Experiment Study

Patient Preference and Adherence, 2022
Min Yang,1 Jingdong Chao,2 Mirko Fillbrunn,1 Usha G Mallya,3 Min-Jung Wang,1 Leigh Franke,1 Lauren Cohn,4,5 Siddhesh Kamat2 1Analysis Group, Inc, Boston, MA, USA; 2Regeneron Pharmaceuticals, Inc, Tarrytown, NY, USA; 3Sanofi, Boston, MA, USA; 4Section of ...
Yang M, Chao J, Fillbrunn M, Mallya UG, Wang MJ, Franke L, Cohn L, Kamat S   +7 more
doaj  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Ultracentrifugation and Ultrafiltration Differentially Alter the Composition and Functionality of the Biomolecular Corona of Extracellular Vesicles

Journal of Extracellular Biology
While extracellular vesicles (EVs) are increasingly recognized for their diagnostic and therapeutic potential, many unknowns remain. An emerging and important concept in EV biology is the EV biomolecular corona, a dynamic layer of absorbed biomolecules ...
Frederic St‐Denis‐Bissonnette, Hala Halabi, Marybeth Creskey, Melanie Kirkby, Xu Zhang, Dylan Burger, Lisheng Wang, Jessie R. Lavoie   +7 more
doaj   +1 more source

The effect of light-gray forest soil tilling systems on the yield and quality of oat grain in the Nizhny Novgorod region

Аграрная наука Евро-Северо-Востока, 2020
The research was conducted in the Nizhny Novgorod region in 2019 on light gray forest soil in the pea-oat crop rotation link. Studied was the effect of soil tillage systems (traditional mouldboard tillage with mouldboard plow; non- mouldboard "deep ...
A. V. Ivenin, A. P. Sakov
doaj   +1 more source

Biological assays with special reference to biological standards [PDF]

Journal of Hygiene, 1950
A paper on biological assays and biological standards might be expected to start with a definition. What is a biological assay and what is a biological standard? However, I shall for the moment make the somewhat doubtful assumption that we all know the answer to those questions but shall return to them later, making a start meanwhile by discussing some
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Exploring Definitions and Predictors of Severe Asthma Clinical Remission Post-Biologic in Adults. [PDF]

RATIONALE: There is no consensus on criteria to include in an asthma remission definition in real-life. Factors associated with achieving remission post-biologic-initiation remain poorly understood.
Ulrik, CS, Faregås, M, Christoff, GC, Bergeron, C, Martin, N, Popov, TA, Pfeffer, PE, Lehtimäki, L, Porsbjerg, CM, Al-Lehebi, RO, Scelo, G, Peters, M, Canonica, GW, Fernandez Sanchez, MJ, Al-Ahmad, M, Bjerrum, AS, Iwanaga, T, Taillé, C, Busby, J, Fonseca, JA, Dorscheid, DR, Altraja, A, Torres-Duque, CA, Tran, TN, von Bülow, A, Kuna, P, Charriot, J, Katial, R, Tsai, M-J, Price, DB, Matsumoto, H, Hew, M, Gibson, PG, Larenas-Linnemann, DES, Cano Rosales, DJ, Wang, E, Bulathsinhala, L, Cosio, BG, Heaney, LG, Koh, MS, Le, TT, Perez-de-Llano, L, Heffler, E, Menzies-Gow, AN, Upham, JW, Mahboub, B, Papadopoulos, NG, Wechsler, ME, Bjermer, LH, Goh, CYY, Sadatsafavi, M, Rhee, CK, Denton, EJ, Carter, VA, Patel, P, Tran, Trung N., Al-Lehebi, Riyad O, Dorscheid, Delbert, Patel, Pujan, Dorscheid, Delbert R, Pfeffer, Paul, Bjermer, Leif, Cano Rosales, Diana J., Ulrik, Charlotte S., Al-Lehebi, Riyad, Denton, Eve, Martin, Neil, Le, Tham T., Carter, Victoria A., Koh, Mariko S, Rhee, Chin, Fernandez Sanchez, Maria J, Goh, Celine Y Y, Papadopoulos, Nikolaos, Upham, John W., Upham, John W, Gibson, Peter, Gibson, Peter G, Tran, Trung N, Kuna, Piotr, Christoff, George, Lehtimäki, Lauri, Ulrik, Charlotte, Heaney, Liam G, Lund University., Iwanaga, Takashi, Rhee, Chin Kook, Popov, Todor, Koh, Mariko Siyue, Menzies-Gow, Andrew N, Popov, Todor A, Price, David B, Price, D.B.,, Busby, John, Heaney, Liam G., Canonica, Giorgio W., Goh, Celine Y. Y., Larenas-Linnemann, Désirée E. S., Price, David B., Canonica, Giorgio, Cano-Rosales, Diana Jimena, Heffler, Enrico, Cosio, Borja, Fernandez Sanchez, Maria, Bergeron, Celine, Bjerrum, Anne, Wang, Eileen, Goh, Celine Y.Y., Altraja, Alan, Bjermer, L.H.,, Wechsler, Michael E, Al-Lehebi, Riyad O., Patel, Pujan H, Fonseca, João, Mahboub, Bassam, Koh, Mariko, Popov, Todor A., Dorscheid, Delbert R., Pfeffer, Paul E, Rhee, Chin K, Denton, Eve J., Tran, Trung, Papadopoulos, Nikolaos G., Le, Tham T, Bergeron , Celine, Menzies-Gow, Andrew N., Tsai, Ming-Ju, von Bülow, Anna, Wechsler, Michael E., Papadopoulos, Nikolaos G, Fernandez-Sanchez, Maria Jose, Canonica, Giorgio W, Fernandez Sanchez, Maria J., Larenas-Linnemann, Désirée E.S., Pfeffer, Paul E., Fonseca, João A, Le, Tham, Scelo, Ghislaine, Bjermer, Leif H., Taillé, Camille, Bjerrum, Anne S, Porsbjerg, Celeste, Heaney, Liam, Fagerås, Malin, Larenas-Linnemann, Désirée, Ulrik, Charlotte S, Sadatsafavi, Mohsen, Larenas-Linnemann, Desir ee E.S., Torres-Duque, Carlos, Christoff, George C., Koh, Mariko S., Perez de Llano, Luis, Christoff, George C, Charriot, Jeremy, Torres-Duque, Carlos A., et al., Hew, Mark, Bjermer, Leif H, Perez-De-Llano, L., Katial, Rohit, Fonseca, João A., Carter, Victoria, Al-Ahmad, Mona, Porsbjerg, Celeste M., Torres-Duque, Carlos A, Perez-De-Llano, L.,, Cosio, Borja G, Suppli Ulrik, Charlotte, Cosio, Borja G., Faregås, Malin, Bjermer, L.H., Matsumoto, Hisako, Peters, Matthew, Denton, Eve J, Bjerrum, Anne S., Menzies-Gow, Andrew, Upham, John, Wechsler, Michael, Carter, Victoria A, Price, D.B., Porsbjerg, Celeste M, Bulathsinhala, Lakmini, Perez-de-Llano, Luis, Cano Rosales, Diana J, Price, David, Larenas-Linnemann, Désirée E S, Gibson, Peter G., Cano Rosales, Diana, Rhee, Chin K., Tsai, Ming Ju   +189 more
core   +3 more sources

Biological information specialists for biological informatics.

Journal of biomedical discovery and collaboration, 2007
Data management and integration are complicated and ongoing problems that will require commitment of resources and expertise from the various biological science communities. Primary components of successful cross-scale integration are smooth information management and migration from one context to another.
Heidorn, P. Bryan, Palmer, Carole L., Wright, Daniel T.   +2 more
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

IL-12p35 Inhibits Neuroinflammation and Ameliorates Autoimmune Encephalomyelitis

Frontiers in Immunology, 2017
Multiple sclerosis (MS) is an inflammatory demyelinating disease in which cytokines produced by immune cells that infiltrate the brain and spinal cord play a central role.
Jin Kyeong Choi, Ivy M. Dambuza, Chang He, Chang He, Cheng-Rong Yu, Anita N. Uche, Mary J. Mattapallil, Rachel R. Caspi, Charles E. Egwuagu   +8 more
doaj   +1 more source