Results 71 to 80 of about 302,285 (314)
25 years of biologic DMARDs in rheumatology
, 2023 2023 marks 25 years since the approval of the first biologic drug in rheumatology. In this Viewpoint, five rheumatology researchers discuss how biologic therapy has transformed clinical practice, reflecting on their own experience, past and current ...
Maini, Ravinder N +4 more
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
BIOLOGIC ARMAMENTARIUM IN PSORIASIS [PDF]
, 2016 Psoriasis is an autoimmune disease and further classed as a chronic inflammatory skin condition serving as global burden. Moderate to severe psoriasis can be treated with conventional therapies.
Sashidharan, Nithin, Pai, Ganesh
core +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Predictors of biologic treatment of psoriasis: a non-interventional study
, 2014 Luis Puig1, Tao Fan,2 Qian Ding,2 Nancy E Smith2 1Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; 2Global Health Outcomes, Merck and Co., Inc., USA Background: Biologic ...
Puig L, Ding Q, Smith NE, Fan T
core
Drug Design, Development and Therapy, 2020 Harsha H Kariyawasam,1– 3 Louisa K James,4 Simon B Gane2,3 1Department of Specialist Allergy and Clinical Immunology, Royal National ENT Hospital, University College London Hospitals NHS Foundation Trust, London, UK; 2Department of Rhinology, Royal
Kariyawasam HH, James LK, Gane SB
doaj
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Mechanisms Underlying Lichen Planus in Association with Biologic Therapy [PDF]
Alexa S Podolsky,1 Shari R Lipner2 1Renaissance School of Medicine, Stony Brook University, New York, NY, USA; 2Department of Dermatology, Weill Cornell Medicine, New York, NY, USACorrespondence: Shari R Lipner, Department of Dermatology, Weill Cornell ...
Podolsky AS, Lipner SR
core
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Efficacy, tolerability and safety of biologic therapy in rheumatoid disease: patient considerations
, 2010 Sarah Horton1, Maya H Buch2, Paul Emery21Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds, 2NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UKAbstract ...
Horton, Sarah +5 more
core +1 more source