Results 71 to 80 of about 310,970 (312)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Mechanisms Underlying Lichen Planus in Association with Biologic Therapy [PDF]
Alexa S Podolsky,1 Shari R Lipner2 1Renaissance School of Medicine, Stony Brook University, New York, NY, USA; 2Department of Dermatology, Weill Cornell Medicine, New York, NY, USACorrespondence: Shari R Lipner, Department of Dermatology, Weill Cornell ...
Podolsky AS, Lipner SR
core
The Demonstration of Biologic Experiments by Optical Projections Methods
THE DEMONSTRATION OF BIOLOGIC EXPERIMENTS BY OPTICAL PROJECTIONS METHODS The Demonstration of Biologic Experiments by Optical Projections Methods (10 ...
Biskind, Morton S.
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Predictors of biologic treatment of psoriasis: a non-interventional study
Luis Puig1, Tao Fan,2 Qian Ding,2 Nancy E Smith2 1Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; 2Global Health Outcomes, Merck and Co., Inc., USA Background: Biologic ...
Puig L, Ding Q, Smith NE, Fan T
core
Conventional immunosuppressive agents have been traditionally used for the treatment of noninfectious uveitis. Recent developments in genetic engineering have made it possible to synthesize proteins that target specific molecules playing role in the ...
Sinan Emre, ‹lknur Tu¤al Tutkun
core +1 more source
Harsha H Kariyawasam,1– 3 Louisa K James,4 Simon B Gane2,3 1Department of Specialist Allergy and Clinical Immunology, Royal National ENT Hospital, University College London Hospitals NHS Foundation Trust, London, UK; 2Department of Rhinology, Royal
Kariyawasam HH, James LK, Gane SB
doaj
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source

