Results 81 to 90 of about 302,285 (314)
PharmaceuticsBackground/Objectives: For several decades, protein drugs (biologics) made in cell cultures have been delivered as sterile injections, decreasing their affordability and patient preference.
Henry Daniell +6 more
doaj +1 more source
International Journal of Rheumatology, 2012 de Carvalho, Jozélio Freire +2 more
openaire +2 more sources
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
An update for Halyomorpha halys (Stål, 1855) (Hemiptera, Pentatomidae) distribution in Belgium [PDF]
Biodiversity Data JournalThe brown marmorated stink bug, Halyomorpha halys, represents an important insect pest and subsequently an important agricultural threat due to its polyphagous feeding habits and adaptability to diverse climates.
Grégoire Noël +5 more
doaj +3 more sources
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Introduction The treatment of Behçet’s disease has improved significantly with the introduction of biologic therapies. However, there is still a need for more information about their use.
Afshin Borhani Haghighi +4 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Advancements in the Study of Biologic Agents in Comorbidities of Psoriasis: A Literature Review
, 2023 Yuhan Wang,1,* Ping Zhang,1,* Yu Lv,1 Yu Deng,2 Ming Yao,3 Lin Wang,1 Guangtao Pan3 1College of Traditional Chinese Medicine, Hubei University of Chinese Medicine, Wuhan, Hubei Province, People’s Republic of China; 2Department of Encephalopathy ...
Pan G +6 more
core
Latest Insights on the Relationship Between Symptoms and Biologic Findings in Adults with Eosinophilic Esophagitis. [PDF]
, 2018 Patients with eosinophilic esophagitis (EoE) present with symptoms accompanied by behavioral adaptions to living with this condition. These include swallowing- and nonswallowing-associated pain in adulthood.
Safroneeva, Ekaterina +8 more
core +1 more source
Bimekizumab for the Treatment of Psoriasis: A Review of the Current Knowledge
Psoriasis: Targets and Therapy, 2022 Angelo Ruggiero, Luca Potestio, Elisa Camela Snr, Gabriella Fabbrocini, Matteo Megna Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, 80131, ItalyCorrespondence: Angelo Ruggiero, Section of ...
Ruggiero A +4 more
doaj