Results 91 to 100 of about 9,475,608 (309)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Examining the impact of nanotechnology on medical and environmental sciences from the nanometric tools perspective [PDF]
The idea of the technology of molecular engineering or nanotechnology was first proposed by Richard Fieman in 1959. Nanotechnology is, in essence, the technology of breaking down the molecular structures with an atomic precision.
Cheraghi A, Bahrani N, Malekfar R
doaj
Surface modification of poly(ε-caprolactone) electrospun fibers with bone powder by DBD [PDF]
Poly(ε-caprolactone) (PCL) is a biodegradable polyester with promising properties in tissue engineering, particularly in the creation of living structures for regenerative medicine.
Marcos Rodrigues Oliveira +10 more
doaj +1 more source
Boolean Models of Bistable Biological Systems
This paper presents an algorithm for approximating certain types of dynamical systems given by a system of ordinary delay differential equations by a Boolean network model.
A. Novick +16 more
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Sleep deprivation and carcinogenesis: the role of melatonin
Sleep is a biological manifestation which there is a periodic alternation between synchronized and desynchronized cerebral electrical activity. Although sleep occupies approximately a third of the human lifespan, the amount of time humans spend awake has
Juliana Noguti, Daniel Araki Ribeiro
doaj +1 more source
Anterior tooth fracture as a result of traumatic injuries, is frequently encountered in endodontic practice. Proper reconstruction of extensively damaged teeth can be achieved through the fragment reattachment procedure known as “biological restoration.” This case report refers to the esthetics and functional recovery of extensively damaged maxillary ...
Kumar, B. Suresh +3 more
openaire +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source

