Results 91 to 100 of about 9,475,608 (309)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Examining the impact of nanotechnology on medical and environmental sciences from the nanometric tools perspective [PDF]

open access: yesحیات, 2004
The idea of the technology of molecular engineering or nanotechnology was first proposed by Richard Fieman in 1959. Nanotechnology is, in essence, the technology of breaking down the molecular structures with an atomic precision.
Cheraghi A, Bahrani N, Malekfar R
doaj  

Surface modification of poly(ε-caprolactone) electrospun fibers with bone powder by DBD [PDF]

open access: yesPolímeros
Poly(ε-caprolactone) (PCL) is a biodegradable polyester with promising properties in tissue engineering, particularly in the creation of living structures for regenerative medicine.
Marcos Rodrigues Oliveira   +10 more
doaj   +1 more source

Boolean Models of Bistable Biological Systems

open access: yes, 2009
This paper presents an algorithm for approximating certain types of dynamical systems given by a system of ordinary delay differential equations by a Boolean network model.
A. Novick   +16 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Sleep deprivation and carcinogenesis: the role of melatonin

open access: yesSleep Science, 2012
Sleep is a biological manifestation which there is a periodic alternation between synchronized and desynchronized cerebral electrical activity. Although sleep occupies approximately a third of the human lifespan, the amount of time humans spend awake has
Juliana Noguti, Daniel Araki Ribeiro
doaj   +1 more source

Biological post

open access: yesJournal of Pharmacy and Bioallied Sciences, 2015
Anterior tooth fracture as a result of traumatic injuries, is frequently encountered in endodontic practice. Proper reconstruction of extensively damaged teeth can be achieved through the fragment reattachment procedure known as “biological restoration.” This case report refers to the esthetics and functional recovery of extensively damaged maxillary ...
Kumar, B. Suresh   +3 more
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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