Results 91 to 100 of about 10,798 (169)
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Tensometric tremorography in high-precision medical diagnostic systems
, 2018 Zoya Aleksanyan,1 Olga Bureneva,2 Nikolay Safyannikov2 1Institute of the Human Brain, Russian Academy of Sciences, Saint Petersburg, Russia; 2Department of Computer Science and Engineering, Saint-Petersburg State Electrotechnical University “LETI ...
Safyannikov N, Aleksanyan Z, Bureneva O
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Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Refinement of artificial intelligence-based systems for diagnosing and predicting river health
, 2011 Environment Agency Technical Report EMC/WP06 077. This report presents the results of a project funded by the Environment Agency which builds on the previous creation of two software systems to diagnose and predict river health from biological and ...
TRIGG, David +6 more
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Analysis of volatile organic compounds in breath as a potential diagnostic modality in disease monitoring [PDF]
, 2011 The use of breath odours in medical diagnosis dates back to classical times, though in its modern form the technique is only a few decades old. There are several breath tests in common clinical use, though all of them involve administration of a known or
Patel, Mitesh Kantilal
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Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Saliva as a Biological Fluid in SARS-CoV-2 Detection
Background: The polymerase chain reaction of upper respiratory tract swab samples was established as the gold standard procedure for diagnosing SARS-CoV-2 during the COVID pandemic.
Rafael Plana Simões +29 more
core +1 more source
Applications of Raman spectroscopy to urology [PDF]
, 2006 Raman spectroscopy is an optical technique that can interrogate biological tissues. In doing so it gives us an understanding of the changes in the molecular structure that are associated with disease development.
Hart Prieto, Maria Consuelo
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source