Results 11 to 20 of about 10,259,014 (319)

Synthesis of New (E)-2-(1H-Indole-3-ylcarbonyl)-3-heteroaryl-acrylonitriles via Microwave-Assisted Knoevenagel Condensation

Journal of Chemistry, 2017
Given the broad spectrum of biological uses of heteroaryl-acrylonitrile derivatives, it is necessary to find simple methods to synthesize and diversify this family of compounds.
Adriana V. Treuer, Pedro De-La-Torre, Margarita I. Gutiérrez   +2 more
doaj   +1 more source

Exercise Serum Alters Genes Related Mitochondria in Cardiomyocyte Culture Cell

Jurnal Pendidikan Jasmani dan Olahraga, 2020
Exercise-induced hearth muscle adaptation is important for physiological process after exercise. This adaptation will ensure basal mitochondrial homeostasis and as a part of the mitochondria quality control.
Ronny Lesmana, Wibowo Budi Prasetyo, Hamidie Ronald Daniel Ray, Vita Murniati Tarawan, Hanna Goenawan, Iwan Setiawan, Yuni Susanti Pratiwi, Nova Sylviana Juliati, Unang Supratman   +8 more
doaj   +1 more source

A Mild Synthesis of New Aryl Vinyl Ethers and Diethyl 1-[(Alkyl)(cyano)methyl]vinylphosphonates via the Substitution of a 2,3-Difunctional Allyl Bromide

The Scientific World Journal, 2014
A novel class of aryl vinyl ethers 3 and diethyl 3-cyano-3-alkylprop-1-en-2-ylphosphonates 4 has been prepared, respectively, from coupling reaction of diethyl 1-(bromomethyl)-2-cyanovinylphosphonate 2 with phenols and Gilman reagents.
Asma Fray, Jihène Ben Kraïem, Aïcha Arfaoui, Hassen Amri   +3 more
doaj   +1 more source

Naturally Occurring Yeasts Associated with Thaumatotibia leucotreta Can Enhance the Efficacy of the Cryptophlebia Leucotreta Granulovirus

Pathogens, 2023
Yeasts associated with lepidopteran pests have been shown to play a role in their survival, development, and oviposition preference. It has been demonstrated that combining these yeasts with existing biological control agents can enhance their efficacy ...
Marcel van der Merwe, Michael D. Jukes, Caroline Knox, Sean D. Moore, Martin P. Hill   +4 more
doaj   +1 more source

Biological Activities of Stilbenoids [PDF]

International Journal of Molecular Sciences, 2018
Stilbenoids are a group of naturally occurring phenolic compounds found in various plant species. They share a common backbone structure known as stilbene, but differ in the nature and position of substituents. Stilbenoids are classified as phytoalexins, which are antimicrobial compounds produced de novo in plants to protect against fungal infection ...
Bolanle Akinwumi, Kimberly-Ann Bordun, Hope Anderson   +2 more
openaire   +2 more sources

Type 2 diabetes and obesity induce similar transcriptional reprogramming in human myocytes

Genome Medicine, 2017
Background Skeletal muscle is one of the primary tissues involved in the development of type 2 diabetes (T2D). The close association between obesity and T2D makes it difficult to isolate specific effects attributed to the disease alone.
Leif Väremo, Tora Ida Henriksen, Camilla Scheele, Christa Broholm, Maria Pedersen, Mathias Uhlén, Bente Klarlund Pedersen, Jens Nielsen   +7 more
doaj   +1 more source

Structural Basis of 2-Phenylamino-4-phenoxyquinoline Derivatives as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

Molecules, 2022
New target molecules, namely, 2-phenylamino-4-phenoxyquinoline derivatives, were designed using a molecular hybridization approach, which was accomplished by fusing the pharmacophore structures of three currently available drugs: nevirapine, efavirenz ...
Arthit Makarasen, Suwicha Patnin, Pongsit Vijitphan, Nanthawan Reukngam, Panita Khlaychan, Mayuso Kuno, Pakamas Intachote, Busakorn Saimanee, Suchada Sengsai, Supanna Techasakul   +9 more
doaj   +1 more source

Design and Synthesis of Novel Tetrahydroquinoline/1,2,3-Triazole Compound Derivatives and Their Anticholinergic Activity as Potential Anti-Alzheimer Agents

Chemistry Proceedings
This research focuses on synthesizing novel tetrahydroquinoline–1,2,3-triazole hybrids as potential agents for neurodegenerative diseases, particularly Alzheimer’s disease (AD).
Cristóbal Dinamarca, Mercedes Pinochet, Margarita Gutiérrez   +2 more
doaj   +1 more source

lncRNA LINC00152 knockdown suppressed hepatic cancer biological activity

Archives of Medical Science, 2020
Introduction Hepatic cancer is one of the most lethal cancers and has a poor prognosis. The purpose of this study was to evaluate whether lncRNA LINC 00152 had effects on the development of hepatic cancer and the related mechanisms.
Yajun Ma, Xuli Yang, Yong Xu, Rongping Zhou, Gang Chen, Deseng Fan, Shikun Luo, Zhili Shen, Dong Yang   +8 more
doaj   +1 more source

Derivatives of Isoindoline, Synthesis and Biological Activity. II. Biological Activity of Derivatives of Isoindoline [PDF]

Kemija u Industriji, 2014
The derivatives of isoindolines show different biological activity in vitro and in vivo and it is hopeful that some of the compounds of this group will develop into new efficient drugs for different types of diseases in the future.
Sović, I., Karminski-Zamola, G.
doaj   +1 more source