Results 41 to 50 of about 8,263,078 (268)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Biologically active compounds isolated from Centipeda and their biological activity as antioxidant and antiinflammatory agents [PDF]

, 2012
Compounds having useful biological activity, particularly antioxidant and anti-​inflammatory activity, derived from Centipeda cunninghamii, and biol. active derivatives thereof, pharmaceutical compns.
Beattie, Karren, Gabriel, Brigitte, Stevenson, Lesley, Leach, David N.   +3 more
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Plant Essential Oil with Biological Activity II

Essential oils (EOs) are some of the most important natural products due to their various biological applications. In fact, many EOs explain crucial antimicrobial activities against several phyto-, food, and human diseases; hence, they are considered ...
Paola Zinno, Giulia Ranaldi, Sofia Allegra, Gabriele Lombardi, Alberto Finamore, Barbara Guantario, Giancarlo Fascella, Antonio Raffo and Marianna Roselli, Michele Massimo Mammano   +8 more
core   +1 more source

Synthesis of N-p-Fluorothiosemicarbazone and of Bis(N-p-Fluorophenylthiourea): Crystal Structure and Conformational Analysis of N,N′-Bis(4-Fluorophenyl)Hydrazine-1,2-Bis(Carbothioamide)

Molbank
The reaction of the phosphonated hydrazone (2-hydrazineylidenepropyl) diphenylphosphine oxide 1 with p-fluorophenyl-isothiocyanate yields as a major product the thiosemicarbazone Ph2P(=O)CH2{C=N-NH(C=S)-N(H)C6H4F}CH3 (2-(1-(diphenylphosphoryl)propan-2 ...
Sirine Salhi, Dorra Kanzari-Mnallah, Isabelle Jourdain, Michael Knorr, Carsten Strohmann, Jan-Lukas Kirchhoff, Hédi Mrabet, Azaiez Ben Akacha   +7 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Crystal structure of (E)-2-(benzo[d]thiazol-2-yl)-3-(pyridin-3-yl)acrylonitrile)

Zeitschrift für Kristallographie - New Crystal Structures, 2016
C15H9N3S, triclinic, P1̅ (no. 2), a = 9.5737(5) Å, b = 12.0958(4) Å, c = 12.2705(7) Å, α = 64.083(5) Å, β = 80.907(4) Å, γ = 82.800(4), V = 1259.44(11) Å3, Z = 4, Rgt(F) = 0.0460, wRref(F2) = 0.140, T = 293(2) K.
De-La-Torre Pedro, Gutierrez Margarita, Caballero Julio, Trilleras Jorge, Astudillo Luis, Cardenas Alejandro, Brito Ivan   +6 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source