Results 41 to 50 of about 16,493,208 (361)

Structural Basis of 2-Phenylamino-4-phenoxyquinoline Derivatives as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

open access: yesMolecules, 2022
New target molecules, namely, 2-phenylamino-4-phenoxyquinoline derivatives, were designed using a molecular hybridization approach, which was accomplished by fusing the pharmacophore structures of three currently available drugs: nevirapine, efavirenz ...
Arthit Makarasen   +9 more
doaj   +1 more source

Active Biological Materials [PDF]

open access: yesAnnual Review of Physical Chemistry, 2009
Cells make use of dynamic internal structures to control shape and create movement. By consuming energy to assemble into highly organized systems of interacting parts, these structures can generate force and resist compression, as well as adaptively change in response to their environment.
Daniel A, Fletcher, Phillip L, Geissler
openaire   +2 more sources

Biological Activity of Ionic Liquids and Their Application in Pharmaceutics and Medicine.

open access: yesChemical Reviews, 2017
Ionic liquids are remarkable chemical compounds, which find applications in many areas of modern science. Because of their highly tunable nature and exceptional properties, ionic liquids have become essential players in the fields of synthesis and ...
K. S. Egorova, E. Gordeev, V. Ananikov
semanticscholar   +1 more source

Biological Activity of Berberine—A Summary Update

open access: yesToxins, 2020
Berberine is a plant metabolite belonging to the group of isoquinoline alkaloids with strong biological and pharmacological activity. Currently, berberine is receiving considerable interest due to its anticancer activity based on many biochemical ...
Anna Och, Rafał Podgórski, R. Nowak
semanticscholar   +1 more source

The chemistry and biological activity of the Hyacinthaceae [PDF]

open access: yes, 2013
Covering: 1914 to 2012The Hyacinthaceae (sensu APGII), with approximately 900 species in about 70 genera, can be divided into three main subfamilies, the Hyacinthoideae, the Urgineoideae and the Ornithogaloideae, with a small fourth subfamily the ...
Schwikkard, Sianne L.   +5 more
core   +2 more sources

Type 2 diabetes and obesity induce similar transcriptional reprogramming in human myocytes

open access: yesGenome Medicine, 2017
Background Skeletal muscle is one of the primary tissues involved in the development of type 2 diabetes (T2D). The close association between obesity and T2D makes it difficult to isolate specific effects attributed to the disease alone.
Leif Väremo   +7 more
doaj   +1 more source

Review of the synthesis and biological activity of thiazoles

open access: yesSynthetic Communications, 2020
This study covers the literature documents available on the chemistry of preparation of thiazoles. Additionally, we cover the biological activities of certain thiazoles.
Sukinah H. Ali, A. R. Sayed
semanticscholar   +1 more source

Freezing nucleation apparatus puts new slant on study of biological ice nucleators in precipitation [PDF]

open access: yes, 2014
For decades, drop-freezing instruments have contributed to a better understanding of biological ice nucleation and its likely implications for cloud and precipitation development. Yet, current instruments have limitations.
Stopelli, Emiliano   +12 more
core   +1 more source

Derivatives of Isoindoline, Synthesis and Biological Activity. II. Biological Activity of Derivatives of Isoindoline [PDF]

open access: yesKemija u Industriji, 2014
The derivatives of isoindolines show different biological activity in vitro and in vivo and it is hopeful that some of the compounds of this group will develop into new efficient drugs for different types of diseases in the future.
Sović, I., Karminski-Zamola, G.
doaj   +1 more source

BIOLOGICAL ACTIVITIES OF LEUPEPTINS

open access: yesThe Journal of Antibiotics, 1969
Leupeptins, leupeptin Pr and leupeptin Ac, strongly inhibit proteolysis by plasmin, trypsin and papain, but do not inhibit proteolysis by α-chymotrypsin. The inhibition is competitive with substrates. The inhibitory effect on esterolysis by plasmin and trypsin is weaker than on proteolysis.
TAKAAKI AOYAGI   +7 more
openaire   +3 more sources

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