Results 311 to 320 of about 16,187,582 (338)

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

In Silico-Designed TGFβRI/TGFβRII Receptor Complex Peptide Inhibitors Exhibit Biological Activity In Vitro. [PDF]

J Cell Mol Med
Plichta J, Karbownik M, Kuna P, Panek M.
europepmc   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Comparative Analysis of <i>Lespedeza</i> Species: Traditional Uses and Biological Activity of the Fabaceae Family. [PDF]

Molecules
Chitiala RD, Lungu II, Marin GA, Mitran AM, Caba IC, Lungu A, Robu S, Mircea C, Stefanache A, Hancianu M, Cioanca O.   +10 more
europepmc   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Exploring the biological activity and setting dynamics of a novel polydopamine-based root repair material. [PDF]

J Oral Biol Craniofac Res
Rao LN, Shetty A, Isloor AM, Nayak S, Kumar M, Shetty K J, Venkatesh M.   +6 more
europepmc   +1 more source

Genotypes of Sechium spp. as a Source of Natural Products with Biological Activity. [PDF]

Life (Basel)
Cadena-Iñiguez J, Arévalo-Galarza ML, Santiago-Osorio E, Aguiñiga-Sánchez I, Cadena-Zamudio JD, Soto-Hernández M, Ramírez-Rodas YC, Ruiz-Posadas LDM, Salazar-Aguilar S, Cisneros-Solano VM.   +9 more
europepmc   +1 more source

Phytochemical profiles and biological activity of <i>Myrsine africana</i> L.: a comprehensive review. [PDF]

Front Pharmacol
Moges GW, Manahelohe GM, Assege MA, Tasew BS, Molla DK, Belew AA.   +5 more
europepmc   +1 more source

Medicinal Potential of Broussonetia papyrifera: Chemical Composition and Biological Activity Analysis. [PDF]

Plants (Basel)
Li Y, Huang R, Zhang W, Chen Q, Wang Q, Ye J, Xu F.   +6 more
europepmc   +1 more source